Franck Borgèse
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View article: A new regulation mechanism for KCNN4, the Ca2+-dependent K+ channel, by molecular interactions with the Ca2+pump PMCA4b
A new regulation mechanism for KCNN4, the Ca2+-dependent K+ channel, by molecular interactions with the Ca2+pump PMCA4b Open
View article: Supplementary Figure 5 from SIGMAR1 Regulates Membrane Electrical Activity in Response to Extracellular Matrix Stimulation to Drive Cancer Cell Invasiveness
Supplementary Figure 5 from SIGMAR1 Regulates Membrane Electrical Activity in Response to Extracellular Matrix Stimulation to Drive Cancer Cell Invasiveness Open
Sig1R promotes hERG- and AKT-dependent FDM-induced cell spreading, VEGF secretion and endothelial transmigration
View article: Supplementary Figure 4 from SIGMAR1 Regulates Membrane Electrical Activity in Response to Extracellular Matrix Stimulation to Drive Cancer Cell Invasiveness
Supplementary Figure 4 from SIGMAR1 Regulates Membrane Electrical Activity in Response to Extracellular Matrix Stimulation to Drive Cancer Cell Invasiveness Open
Sig1R silencing inhibits CRC HCT-116 cell motility
View article: Data from SIGMAR1 Regulates Membrane Electrical Activity in Response to Extracellular Matrix Stimulation to Drive Cancer Cell Invasiveness
Data from SIGMAR1 Regulates Membrane Electrical Activity in Response to Extracellular Matrix Stimulation to Drive Cancer Cell Invasiveness Open
The sigma 1 receptor (Sig1R) is a stress-activated chaperone that regulates ion channels and is associated with pathologic conditions, such as stroke, neurodegenerative diseases, and addiction. Aberrant expression levels of ion channels an…
View article: Supplementary Figure 5 from SIGMAR1 Regulates Membrane Electrical Activity in Response to Extracellular Matrix Stimulation to Drive Cancer Cell Invasiveness
Supplementary Figure 5 from SIGMAR1 Regulates Membrane Electrical Activity in Response to Extracellular Matrix Stimulation to Drive Cancer Cell Invasiveness Open
Sig1R promotes hERG- and AKT-dependent FDM-induced cell spreading, VEGF secretion and endothelial transmigration
View article: Supplementary Figure 4 from SIGMAR1 Regulates Membrane Electrical Activity in Response to Extracellular Matrix Stimulation to Drive Cancer Cell Invasiveness
Supplementary Figure 4 from SIGMAR1 Regulates Membrane Electrical Activity in Response to Extracellular Matrix Stimulation to Drive Cancer Cell Invasiveness Open
Sig1R silencing inhibits CRC HCT-116 cell motility
View article: Data from SIGMAR1 Regulates Membrane Electrical Activity in Response to Extracellular Matrix Stimulation to Drive Cancer Cell Invasiveness
Data from SIGMAR1 Regulates Membrane Electrical Activity in Response to Extracellular Matrix Stimulation to Drive Cancer Cell Invasiveness Open
The sigma 1 receptor (Sig1R) is a stress-activated chaperone that regulates ion channels and is associated with pathologic conditions, such as stroke, neurodegenerative diseases, and addiction. Aberrant expression levels of ion channels an…
View article: Supplementary Figure 2 from SIGMAR1 Regulates Membrane Electrical Activity in Response to Extracellular Matrix Stimulation to Drive Cancer Cell Invasiveness
Supplementary Figure 2 from SIGMAR1 Regulates Membrane Electrical Activity in Response to Extracellular Matrix Stimulation to Drive Cancer Cell Invasiveness Open
Sig1R is associated to β1 integrin and promotes β1 integrin / hERG association without altering β1 integrin membrane expression
View article: Supplementary Figure 3 from SIGMAR1 Regulates Membrane Electrical Activity in Response to Extracellular Matrix Stimulation to Drive Cancer Cell Invasiveness
Supplementary Figure 3 from SIGMAR1 Regulates Membrane Electrical Activity in Response to Extracellular Matrix Stimulation to Drive Cancer Cell Invasiveness Open
Control experiments showing specificity of PLA assay between hERG and β1 integrin
View article: Supplementary Figure 1 from SIGMAR1 Regulates Membrane Electrical Activity in Response to Extracellular Matrix Stimulation to Drive Cancer Cell Invasiveness
Supplementary Figure 1 from SIGMAR1 Regulates Membrane Electrical Activity in Response to Extracellular Matrix Stimulation to Drive Cancer Cell Invasiveness Open
FDM induces a stable increase in hERG current in a Sig1R-dependent manner but does not alter channel maturation
View article: Supplementary Figure 3 from SIGMAR1 Regulates Membrane Electrical Activity in Response to Extracellular Matrix Stimulation to Drive Cancer Cell Invasiveness
Supplementary Figure 3 from SIGMAR1 Regulates Membrane Electrical Activity in Response to Extracellular Matrix Stimulation to Drive Cancer Cell Invasiveness Open
Control experiments showing specificity of PLA assay between hERG and β1 integrin
View article: Supplementary Figure 2 from SIGMAR1 Regulates Membrane Electrical Activity in Response to Extracellular Matrix Stimulation to Drive Cancer Cell Invasiveness
Supplementary Figure 2 from SIGMAR1 Regulates Membrane Electrical Activity in Response to Extracellular Matrix Stimulation to Drive Cancer Cell Invasiveness Open
Sig1R is associated to β1 integrin and promotes β1 integrin / hERG association without altering β1 integrin membrane expression
View article: Supplementary Figure 1 from SIGMAR1 Regulates Membrane Electrical Activity in Response to Extracellular Matrix Stimulation to Drive Cancer Cell Invasiveness
Supplementary Figure 1 from SIGMAR1 Regulates Membrane Electrical Activity in Response to Extracellular Matrix Stimulation to Drive Cancer Cell Invasiveness Open
FDM induces a stable increase in hERG current in a Sig1R-dependent manner but does not alter channel maturation
View article: Cell polarity and adherens junction formation inhibit epithelial Fas cell death receptor signaling
Cell polarity and adherens junction formation inhibit epithelial Fas cell death receptor signaling Open
Finely tuned regulation of epithelial cell death maintains tissue integrity and homeostasis. At the cellular level, life and death decisions are controlled by environmental stimuli such as the activation of death receptors. We show that ce…
View article: KCNQ1 : un nouveau régulateur de la transition épithélio-mésenchymateuse dans les cancers du côlon
KCNQ1 : un nouveau régulateur de la transition épithélio-mésenchymateuse dans les cancers du côlon Open