François Cinotti
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Mistakes in Action: On Clarifying the Phenomenon of Goal-Directedness Open
Common sense tells us that biological systems are goal-directed, and yet the concept remains philosophically problematic. We propose a novel characterization of goal-directed activities as a basis for hypothesizing about and investigating …
Regulation of reinforcement learning parameters captures long‐term changes in rat behaviour Open
In uncertain environments in which resources fluctuate continuously, animals must permanently decide whether to stabilise learning and exploit what they currently believe to be their best option, or instead explore potential alternatives a…
Regulation of the exploration-exploitation trade-off captures long-term changes in rat behaviour Open
In uncertain environments in which resources fluctuate continuously, animals must permanently decide whether to exploit what they currently believe to be their best option, or instead explore potential alternatives in case better opportuni…
Reward-Mediated, Model-Free Reinforcement-Learning Mechanisms in Pavlovian and Instrumental Tasks Are Related Open
Model-free and model-based computations are argued to distinctly update action values that guide decision-making processes. It is not known, however, if these model-free and model-based reinforcement learning mechanisms recruited in operat…
Conserved reward-mediated, reinforcement-learning mechanisms in Pavlovian and instrumental tasks Open
Model-free and model-based computations are argued to distinctly update action values that guide decision-making processes. It is not known, however, if these model-free and model-based reinforcement learning mechanisms recruited in operat…
Bayesian Mapping of the Striatal Microcircuit Reveals Robust Asymmetries in the Probabilities and Distances of Connections Open
The striatum's complex microcircuit is made by connections within and between its D1- and D2-receptor expressing projection neurons and at least five species of interneuron. Precise knowledge of this circuit is likely essential to understa…
Bayesian mapping of the striatal microcircuit reveals robust asymmetries in the probabilities and distances of connections Open
The striatum’s complex microcircuit is made by connections within and between its D1- and D2-receptor expressing projection neurons and at least five species of interneuron. Precise knowledge of this circuit is likely essential to understa…
Impacts of inter-trial interval duration on a computational model of sign-tracking vs. goal-tracking behaviour Open
In the context of Pavlovian conditioning, two types of behaviour may emerge within the population (Flagel et al. Nature, 469(7328): 53-57, 2011). Animals may choose to engage either with the conditioned stimulus (CS), a behaviour known as …
Dopamine regulates the exploration-exploitation trade-off in rats Open
In a volatile environment where rewards are uncertain, successful performance requires a delicate balance between exploitation of the best option and exploration of alternative choices. It has theoretically been proposed that dopamine cont…