Frank J. Palella
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View article: Psychosocial, Behavioral, and HIV-Related Health Among Men Living with HIV Who Have a History of Incarceration
Psychosocial, Behavioral, and HIV-Related Health Among Men Living with HIV Who Have a History of Incarceration Open
Incarceration is intricately linked with the HIV epidemic, with incarcerated individuals exhibiting HIV prevalence rates three times higher than the general population. We used baseline data from the Multicenter AIDS Cohort Study (MACS)/Wo…
View article: Psychosocial, Behavioral, and HIV-Related Health Among Men Living with HIV Who Have a History of Incarceration
Psychosocial, Behavioral, and HIV-Related Health Among Men Living with HIV Who Have a History of Incarceration Open
View article: Direct-Acting Antiviral Initiation Among People With Hepatitis C Virus (HCV) and HIV on Antiretroviral Therapy in the United States and Canada: Factors Driving the HCV Treatment Gap
Direct-Acting Antiviral Initiation Among People With Hepatitis C Virus (HCV) and HIV on Antiretroviral Therapy in the United States and Canada: Factors Driving the HCV Treatment Gap Open
Background People with human immunodeficiency virus (HIV; PWH) are at increased risk of hepatitis C virus (HCV) coinfection and experiencing negative clinical outcomes. We evaluated direct-acting antiviral (DAA) initiation among PWH with H…
View article: Prevalence of chlamydial, gonococcal and syphilis positivity by anatomical site and sex via self-collected biospecimens using at-home testing kits among a large and diverse cohort of men and women enrolled in the MACS/WIHS Combined Cohort Study (MWCCS) in the USA
Prevalence of chlamydial, gonococcal and syphilis positivity by anatomical site and sex via self-collected biospecimens using at-home testing kits among a large and diverse cohort of men and women enrolled in the MACS/WIHS Combined Cohort Study (MWCCS) in the USA Open
Introduction Cisgender men who have sex with men (MSM), transgender women, cisgender women and cisgender men who have sex with women only (MSW) have differential risk of acquiring Chlamydia trachomatis (CT) and Neisseria gonorrhoeae (GC), …
View article: Glycation metabolites predict incident age-related comorbidities and mortality in older people with HIV
Glycation metabolites predict incident age-related comorbidities and mortality in older people with HIV Open
Glycation is a class of modifications arising from non-enzymatic reactions of reducing sugars with proteins, lipids, and/or DNA, generating advanced glycation end-products (AGEs). AGEs are linked to many age-related comorbidities. In respo…
View article: HIV Providers’ Attitudes Towards Telemedicine (Preprint)
HIV Providers’ Attitudes Towards Telemedicine (Preprint) Open
BACKGROUND The COVID-19 pandemic prompted an abrupt transition to telemedicine for HIV care, necessitating an exploration of provider attitudes and experiences to understand future viability and impact. OBJECTIVE We conducted a converge…
View article: Humoral Immunity Against Orthopoxvirus in Vaccinated and Unvaccinated Individuals during 2022 Mpox Outbreak
Humoral Immunity Against Orthopoxvirus in Vaccinated and Unvaccinated Individuals during 2022 Mpox Outbreak Open
Little is known about serological responses to MVA-BN (JYNNEOS) against mpox in elderly individuals with or without HIV. In this study, MVA-BN induced sustained IgG levels regardless of HIV status even up to one year. Birth before 1973 cor…
View article: HIV-Associated Proteomic Signature of Myocardial Fibrosis and Incident Heart Failure
HIV-Associated Proteomic Signature of Myocardial Fibrosis and Incident Heart Failure Open
View article: Expert Consensus Statement on an Updated Definition of Unintended Weight Loss Among Persons With Human Immunodeficiency Virus in the Modern Treatment Era
Expert Consensus Statement on an Updated Definition of Unintended Weight Loss Among Persons With Human Immunodeficiency Virus in the Modern Treatment Era Open
The era of modern antiretroviral therapy (ART) has markedly improved health and survival among persons with human immunodeficiency virus (HIV) (PWH). In the pre-ART era, wasting was associated with HIV disease progression to acquired immun…
View article: Sexual behavior is linked to changes in gut microbiome and systemic inflammation that lead to HIV-1 infection in men who have sex with men
Sexual behavior is linked to changes in gut microbiome and systemic inflammation that lead to HIV-1 infection in men who have sex with men Open
View article: The impact of diabetes mellitus on HIV virologic control: results of the MACS/WIHS combined cohort study
The impact of diabetes mellitus on HIV virologic control: results of the MACS/WIHS combined cohort study Open
Objective: Diabetes mellitus (DM) is associated with lower antiretroviral (ART) drug exposure among persons with HIV (PWH) compared to PWH without DM. The association between DM and virologic control in PWH, however, remains unknown. Metho…
View article: Prepandemic Metabolic Correlates of Coronavirus Disease 2019 (COVID-19) Severity and Long COVID Incidence in People Living With HIV
Prepandemic Metabolic Correlates of Coronavirus Disease 2019 (COVID-19) Severity and Long COVID Incidence in People Living With HIV Open
Host metabolic dysregulation, especially in tryptophan metabolism, is intricately linked to coronavirus disease 2019 (COVID-19) severity and its postacute sequelae (long COVID). People living with human immunodeficiency virus (HIV; PLWH) e…
View article: Transgender Women With Suppressed Testosterone Display Lower Burden of Coronary Disease Than Matched Cisgender Men
Transgender Women With Suppressed Testosterone Display Lower Burden of Coronary Disease Than Matched Cisgender Men Open
Context Cardiovascular disease (CVD) in transgender women (TW) may be affected by gender-affirming hormone therapy (GAHT) and HIV, but few data compare TW on contemporary GAHT to well-matched controls. Objective We compared CVD burden and …
View article: Does Resilience Mediate the Relationship Between Negative Self-Image and Psychological Distress in Middle-Aged and Older Gay and Bisexual Men?
Does Resilience Mediate the Relationship Between Negative Self-Image and Psychological Distress in Middle-Aged and Older Gay and Bisexual Men? Open
Aging gay and bisexual men may have negative self-images due to body image dissatisfaction and internalized ageism, resulting in psychological distress. Gay and bisexual men with HIV may be at greater risk for distress because of research …
View article: Incidence of erectile dysfunction among middle-aged and aging sexual minority men living with or without HIV
Incidence of erectile dysfunction among middle-aged and aging sexual minority men living with or without HIV Open
Introduction: Erectile dysfunction (ED) has been established as a comorbidity among men living with HIV, but comparisons by HIV serostatus of ED incidence in a longitudinal follow-up cohort of men are lacking. We sought to…
View article: Supplemental Figure 5 from Oncogenic Oral Human Papillomavirus Clearance Patterns over 10 Years
Supplemental Figure 5 from Oncogenic Oral Human Papillomavirus Clearance Patterns over 10 Years Open
Supplemental Figure 5: Effect of HPV16 qPCR copynumber(CN) per cell on HPV16 infections.
View article: Data from Oncogenic Oral Human Papillomavirus Clearance Patterns over 10 Years
Data from Oncogenic Oral Human Papillomavirus Clearance Patterns over 10 Years Open
Background:Effective screening for oropharyngeal cancer is lacking. Four oncogenic HPV clearance definitions were explored to understand long-term natural history for persistent oncogenic oral HPV (oncHPV), the precursor of oropharyngeal c…
View article: Supplemental Figure 5 from Oncogenic Oral Human Papillomavirus Clearance Patterns over 10 Years
Supplemental Figure 5 from Oncogenic Oral Human Papillomavirus Clearance Patterns over 10 Years Open
Supplemental Figure 5: Effect of HPV16 qPCR copynumber(CN) per cell on HPV16 infections.
View article: Supplemental Table 2 from Oncogenic Oral Human Papillomavirus Clearance Patterns over 10 Years
Supplemental Table 2 from Oncogenic Oral Human Papillomavirus Clearance Patterns over 10 Years Open
Supplemental Table 2: Multivariate predictors of clearance, across the four different clearance definitions evaluated in this study.
View article: Incidence of erectile dysfunction among middle-aged and aging sexual minority men living with or without HIV
Incidence of erectile dysfunction among middle-aged and aging sexual minority men living with or without HIV Open
Introduction: Erectile dysfunction (ED) has been established as a comorbidity among men living with HIV, but comparisons by HIV serostatus of ED incidence in a longitudinal follow-up cohort of men are lacking. We sought to…
View article: Supplemental Figure 7 from Oncogenic Oral Human Papillomavirus Clearance Patterns over 10 Years
Supplemental Figure 7 from Oncogenic Oral Human Papillomavirus Clearance Patterns over 10 Years Open
Supplemental Figure 7: Effect of HPV type (16 vs non16 oncogenic HPV type) on prevalent (SF7a) incident (SF7b) infections.
View article: Supplemental Table 2 from Oncogenic Oral Human Papillomavirus Clearance Patterns over 10 Years
Supplemental Table 2 from Oncogenic Oral Human Papillomavirus Clearance Patterns over 10 Years Open
Supplemental Table 2: Multivariate predictors of clearance, across the four different clearance definitions evaluated in this study.
View article: Supplemental Figure 4 from Oncogenic Oral Human Papillomavirus Clearance Patterns over 10 Years
Supplemental Figure 4 from Oncogenic Oral Human Papillomavirus Clearance Patterns over 10 Years Open
Supplemental Figure 4: Effect of sex on prevalent (SF4a) incident (SF4b) infections.
View article: Supplemental Figure 6 from Oncogenic Oral Human Papillomavirus Clearance Patterns over 10 Years
Supplemental Figure 6 from Oncogenic Oral Human Papillomavirus Clearance Patterns over 10 Years Open
Supplemental Figure 6: Effect of HIV and CD4 on prevalent (SF6a) incident (SF6b) infections.
View article: Supplemental Table 1 from Oncogenic Oral Human Papillomavirus Clearance Patterns over 10 Years
Supplemental Table 1 from Oncogenic Oral Human Papillomavirus Clearance Patterns over 10 Years Open
Supplemental Table 1: Proportion of 1833 subjects screened who have oncogenic oral HPV DNA and cancer characteristics.
View article: Data from Oncogenic Oral Human Papillomavirus Clearance Patterns over 10 Years
Data from Oncogenic Oral Human Papillomavirus Clearance Patterns over 10 Years Open
Background:Effective screening for oropharyngeal cancer is lacking. Four oncogenic HPV clearance definitions were explored to understand long-term natural history for persistent oncogenic oral HPV (oncHPV), the precursor of oropharyngeal c…
View article: Supplemental Figure 3 from Oncogenic Oral Human Papillomavirus Clearance Patterns over 10 Years
Supplemental Figure 3 from Oncogenic Oral Human Papillomavirus Clearance Patterns over 10 Years Open
Supplemental Figure 3: Effect of age on prevalent (SF3a) incident (SF3b) infections.
View article: Supplemental Figure 4 from Oncogenic Oral Human Papillomavirus Clearance Patterns over 10 Years
Supplemental Figure 4 from Oncogenic Oral Human Papillomavirus Clearance Patterns over 10 Years Open
Supplemental Figure 4: Effect of sex on prevalent (SF4a) incident (SF4b) infections.
View article: Supplemental Figure 2 from Oncogenic Oral Human Papillomavirus Clearance Patterns over 10 Years
Supplemental Figure 2 from Oncogenic Oral Human Papillomavirus Clearance Patterns over 10 Years Open
Supplemental Figure 2: Clearance of prevalent (panel A) and incident (panel B) oral HPV16 infections over 10 years
View article: Supplemental Figure 1 from Oncogenic Oral Human Papillomavirus Clearance Patterns over 10 Years
Supplemental Figure 1 from Oncogenic Oral Human Papillomavirus Clearance Patterns over 10 Years Open
Supplemental Figure 1: Flowchart of the 1833 MACS and WIHS participants in the POPS, how many had oncogenic oral HPV DNA, and how many had additional follow-up of uncleared infections as part of the MOUTH study.