Explanipedia

S2k-Guideline – Sports Pre-Participation Evaluation of the German Society of Sports Medicine and Prevention Open

Christine Joisten, Anja Hirschmüller, Pascal Bauer, Erika Baum, Meinolf Behrens , et al. · 2025

The purpose of this derivative version is to highlight and disseminate the core recommendations to clinicians, sports practitioners, and policy makers in the German-speaking health and sports sector.The benefits of physical activity are un…

Rückenschmerzen im Nachwuchssport: Lumbale Stressverletzungen frühzeitig erkennen Open

Michael Cassel, Josefine Stoll, Frank Mayer · 2025

The Effect of an 8-Week Vegan Diet on the Nutritional Status and Performance of Semi-Professional Soccer Players—Results of the VegInSoc Study Open

Josefine Nebl, Pauline Bruns, Mark S. Meier, Frank Mayer, Martin Smollich , et al. · 2025

Background/Objectives: Although there is an increasing interest among athletes in adopting plant-based diets, there is insufficient research available to determine how a vegan diet affects soccer performance. Methods: This interventional p…

Sports Preparticipation Evaluation for Healthy Adults: A Consensus-Based German Guideline Open

Christine Joisten, Anja Hirschmüller, Pascal Bauer, Erika Baum, Meinolf Behrens , et al. · 2025

Neuromechanical adaptation of a perturbation protocol during treadmill running Open

Mina Khajooei, Andrew Quarmby, Frank Mayer, Tilman Engel · 2025

The ability to adapt to unexpected changes in environments is associated with the risk of running-related injuries. Although gait retraining programs can mitigate injury risk, there is a scarcity of studies focusing on neuromechanical adap…

Sensorimotor Stabilization Exercises With and Without Behavioral Treatment in Low Back Pain: Feasibility and Effects of a Multicenter Randomized Controlled Trial Open

Tilman Engel, Daniel Niederer, Adamantios Arampatzis, Winfried Banzer, Heidrun Beck , et al. · 2025

Participants were highly adherent to the sensorimotor exercise, but showed increased dropout rates, particularly during home-based training. Both interventions proved to be feasible, and although only SMT showed an increased effect on pain…

Finding Predictive Factors of Stabilization Exercise Adherence in Randomized Controlled Trials on Low Back Pain: An Individual Data Reanalysis Using Machine Learning Techniques Open

Ann-Christin Pfeifer, Paul Pfeifer-Schröder, Marcus Schiltenwolf, Lutz Vogt, Christian Schneider , et al. · 2025

Identified predictors could aid in recognizing individuals at higher risk for nonadherence in low back pain exercise therapy settings.

Biomechanical feedback and feedforward responses during perturbed running in asymptomatic individuals Open

Mina Khajooei, Andrew Quarmby, Frank Mayer, Tilman Engel · 2024

Assessment of biomechanical features whilst running on an uneven terrain plays an important role in identifying running-related injury mechanisms. However, feedback and feedforward motor responses and adaptations, an important component of…

Monitoring Cortical and Neuromuscular Activity: Six-month Insights into Knee Joint Position Sense Following ACL Reconstruction Open

Aglaja Busch, Lorena R. R. Gianotti, Frank Mayer, Heiner Baur · 2024

Background Changes in cortical activation patterns after rupture of the anterior cruciate ligament (ACL) have been described. However, evidence of these consequences in the early stages following the incident and through longitudinal monit…

Bewertung von Instrumenten zur Diagnosefindung des Restless-Legs-Syndroms im Kindes- und Jugendalter Open

Julian Mollin, Lisa Klug, Theresa Joost, Uta Beyer, Frank Mayer , et al. · 2024

Zusammenfassung Hintergrund Das Restless-Legs-Syndrom (RLS) ist eine schlafbezogene Bewegungsstörung mit Beinbewegungen, die durch Missempfindungen verursacht werden. Die Symptome treten vorwiegend abends oder nachts auf und bessern sich d…

Elotuzumab, lenalidomide, bortezomib, dexamethasone, and autologous haematopoietic stem-cell transplantation for newly diagnosed multiple myeloma (GMMG-HD6): results from a randomised, phase 3 trial Open

K. Elias, Hartmut Goldschmidt, Kaya Miah, Uta Bertsch, Britta Besemer , et al. · 2024

Bristol Myers Squibb/Celgene and Chugai.

COVID-19 in Female and Male Athletes: Symptoms, Clinical Findings, Outcome, and Prolonged Exercise Intolerance—A Prospective, Observational, Multicenter Cohort Study (CoSmo-S) Open

Manuel Widmann, Roman Gaidai, Isabel Schubert, Maximilian Grummt, Lieselotte Bensen , et al. · 2024

Neuromechanical Adaptation of a Perturbation Protocol During Treadmill Running Open

Mina Khajooei, Andrew Quarmby, Frank Mayer, Tilman Engel · 2024

Correction: Application of eccentric training in various clinical populations: Protocol for a multi-centered pilot and feasibility study in people with low back pain and people with multiple sclerosis Open

Monique Wochatz, Anne Schraplau, Tilman Engel, Mahli M. Zecher, Hadar Sharon , et al. · 2023

[This corrects the article DOI: 10.1371/journal.pone.0270875.].

MobileNVC: Real-time 1080p Neural Video Compression on a Mobile Device Open

Ties van Rozendaal, Tushar Singhal, Hoang Le, Guillaume Sautière, Amir Said , et al. · 2023

Neural video codecs have recently become competitive with standard codecs such as HEVC in the low-delay setting. However, most neural codecs are large floating-point networks that use pixel-dense warping operations for temporal modeling, m…

Unexpected running perturbations: Reliability and validity of a treadmill running protocol with analysis of provoked reflex activity in the lower extremities Open

Andrew Quarmby, Mina Khajooei, Philip Kurtz, Jakob Henschke, Myoung-Hwee Kim , et al. · 2023

Introduction Balance is vital for human health and experiments have been conducted to measure the mechanisms of postural control, for example studying reflex responses to simulated perturbations. Such studies are frequent in walking but le…

Reliability of segmental instability and spinopelvic alignment in athletes with isthmic spondylolisthesis in functional MRI Open

Theresa Joost, Tilman Engel, Lucie Risch, Frank Mayer, M Cassel · 2023

Problem Statement: In athletes with spondylolisthesis, segmental instability and impaired spinopelvic alignment are considered as clinically relevant. Functional MRI in supine and upright position enables a load-dependent acquisition, but …

Reliability of the active knee joint position sense test and influence of limb dominance and sex Open

Aglaja Busch, Christian Bangerter, Frank Mayer, Heiner Baur · 2023

Application of eccentric training in various clinical populations: Protocol for a multi-centered pilot and feasibility study in people with low back pain and people with multiple sclerosis Open

Monique Wochatz, Anne Schraplau, Tilman Engel, Mahli M. Zecher, Hadar Sharon , et al. · 2022

Physical activity and exercise are effective approaches in prevention and therapy of multiple diseases. Although the specific characteristics of lengthening contractions have the potential to be beneficial in many clinical conditions, ecce…

Circulating syndecan-1 and glypican-4 predict 12-month survival in metastatic colorectal cancer patients Open

Axel Muendlein, Luciano Severgnini, Thomas Decker, Christine Heinzle, Andreas Leiherer , et al. · 2022

Cell surface syndecans and glypicans play important roles in the development and prognosis of colorectal cancer (CRC). Their soluble forms from proteoglycan shedding can be detected in blood and have been proposed as new prognostic biomark…

Effectiveness and mechanisms of a multimodal treatment for low back pain: a pragmatic matched cohort study Open

Robin Schäfer, Daniel Niederer, Claudia Levenig, Monika Hasenbring, Thomas Tas , et al. · 2022

Objective To investigate the effectiveness and mechanisms of a multimodal treatment including perturbation exercise. Methods A matched cohort study was conducted. The intervention consists of a 12-week back pain prevention course with pert…

Pheochromocytoma: A Diagnosis Made More Difficult in the COVID-19 Era Open

Frank Mayer · 2022

INTRODUCTION Pheochromocytomas and paragangliomas are rare neuroendocrine tumors that secrete catecholamines. Symptoms of these tumors are related directly to catecholamine excess but can be intermittent and easily misattributed to other m…

Effect of Six-Week Resistance and Sensorimotor Training on Trunk Strength and Stability in Elite Adolescent Athletes: A Randomized Controlled Pilot Trial Open

Steffen Mueller, Juliane Mueller, Josefine Stoll, Frank Mayer · 2022

Intervention in the form of core-specific stability exercises is evident to improve trunk stability. The purpose was to assess the effect of an additional 6 weeks sensorimotor or resistance training on maximum isokinetic trunk strength and…

The prevalence of chronic ankle instability in basketball athletes: a cross-sectional study Open

Chiao‐I Lin, Frank Mayer, Pia‐Maria Wippert · 2022

COVID-19 in German Competitive Sports: Protocol for a Prospective Multicenter Cohort Study (CoSmo-S) Open

Andreas M. Nieß, Manuel Widmann, Roman Gaidai, Christian Gölz, Isabel Schubert , et al. · 2022

Objective: It is unclear whether and to what extent COVID-19 infection poses health risks and a chronic impairment of performance in athletes. Identification of individual health risk is an important decision-making basis for managing the …

Tannins: Natural plant-derived polyhydroxy phenolic compounds with potential for biotechnological and biomedical applications Open

Frank Mayer · 2022

The difference between Tannin and Tannic Acid is that the term Tannin is used to name the group of organic compounds whereas Tannic acid is a type of tannin. Members of the group of Tannins - all of them polyhydroxyphenolic compounds – are…

Feasability of An Eccentric Isokinetic Protocol to Induce Trunk Muscle Damage: A Pilot Study Open

Tilman Engel, Anne Schraplau, Monique Wochatz, Stephan Kopinski, Dominik Sonnenburg , et al. · 2022

Eccentric exercise is discussed as a treatment option for clinical populations, but specific responses in terms of muscle damage and systemic inflammation after repeated loading of large muscle groups have not been conclusively characteriz…

Developing a Nationwide Infrastructure for Therapeutic Drug Monitoring of Targeted Oral Anticancer Drugs: The ON-TARGET Study Protocol Open

Anna M. Mc Laughlin, Eduard Schmulenson, Olga Teplytska, Sebastian Zimmermann, Patrick Opitz , et al. · 2021

Exposure-efficacy and/or exposure-toxicity relationships have been identified for up to 80% of oral anticancer drugs (OADs). Usually, OADs are administered at fixed doses despite their high interindividual pharmacokinetic variability resul…

261 Injuries in long distance racecar drivers: a longitudinal study of pre-participation examinations Open

Josefine Stoll, Lucie Risch, Michael Cassel, Frank Mayer · 2021

Background Professional long distance racecar drivers are exposed to high physical load during races. Athletes have to interact with other racecar drivers during high-speed situations on the track. Additionally G-forces have to be countera…

Inter-rater and inter-session reliability of lumbar paraspinal muscle composition in a mobile MRI device Open

Anne Schomöller, Lucie Risch, Hannes Kaplick, Monique Wochatz, Tilman Engel , et al. · 2021

Objective: To assess the reliability of measurements of paraspinal muscle transverse relaxation times (T2 times) between two observers and within one observer on different time points. Methods: 14 participants (9f/5m, 33 ± 5 years, 176 ± 1…

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