Frank Z. Stanczyk
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View article: OR15-06 Steroids, stress and body mass index interact to accelerate female pubertal development
OR15-06 Steroids, stress and body mass index interact to accelerate female pubertal development Open
Disclosure: L.C. Houghton: None. Y. Wei: None. S.A. Wudy: None. M. Hartmann: None. F.Z. Stanczyk: None. J. Knight: None. I. Andrulis: None. A. Bradbury: None. L. Schwartz: None. S. Buys: None. M. Daly: None. E. John: None. W. Chung: None. …
View article: Chapter 3. Impact of estrogens on hemostasis
Chapter 3. Impact of estrogens on hemostasis Open
It is well established that estrogens increase the risk of both arterial and venous thrombosis. Abnormally high levels of some coagulation factors combined with a decrease in anticoagulation factors contribute to thrombotic risk. Although …
View article: Anti‐Müllerian Hormone Levels Are Associated With Skeletal Maturity in Adolescent Girls: A Longitudinal Study
Anti‐Müllerian Hormone Levels Are Associated With Skeletal Maturity in Adolescent Girls: A Longitudinal Study Open
Background and Aims The role of anti‐Müllerian hormone (AMH), a potential marker of the hypothalamic–pituitary–ovarian axis, is not well established in adolescent females. Typical epidemiologic studies use secondary sexual characteristics …
View article: Prevalence of endometrial hyperplasia and carcinoma in women with polycystic ovarian syndrome
Prevalence of endometrial hyperplasia and carcinoma in women with polycystic ovarian syndrome Open
View article: The rediscovery of estetrol and its implications for estrogen treatment
The rediscovery of estetrol and its implications for estrogen treatment Open
Objectives: To summarize the literature on the rediscovery and clinical exploration of the fourth natural estrogen estetrol (E4), more than 100 years after the discovery of estrone (E1), estradiol (E2), and estriol (E3). Methods: Literatur…
View article: Premature ovarian insufficiency and the risk of breast cancer
Premature ovarian insufficiency and the risk of breast cancer Open
View article: 12270 Adolescent PCOS With Unexpected, Sudden-onset GAD And MDD: A Call For Vigilance In Longitudinal PCOS Care
12270 Adolescent PCOS With Unexpected, Sudden-onset GAD And MDD: A Call For Vigilance In Longitudinal PCOS Care Open
Disclosure: K.I. Sarkisian: None. T. Aliabadi: None. F.Z. Stanczyk: None. Background: Polycystic Ovary Syndrome (PCOS) is a multifaceted endocrine disorder often associated with psychiatric disorders, yet the integration of psychiatric mon…
View article: Estrogen deficiency in the menopause and the role of hormone therapy: integrating the findings of basic science research with clinical trials
Estrogen deficiency in the menopause and the role of hormone therapy: integrating the findings of basic science research with clinical trials Open
Menopause, defined by the cessation of menstrual cycles after 12 months of amenorrhea not due to other causes, is associated with significant hormonal changes, primarily a decrease in estrogen, androgen, and progesterone levels. This revie…
View article: Editorial Board
Editorial Board Open
View article: Progesterone in frozen embryo transfer cycles: assays, circulating concentrations, metabolites, and molecular action
Progesterone in frozen embryo transfer cycles: assays, circulating concentrations, metabolites, and molecular action Open
Programmed or medicated frozen embryo transfer cycles rely on exogenous progesterone (P) administration to prepare the endometrium for implantation and maintain pregnancy. Presently, the optimal route and dose of P replacement for frozen e…
View article: Editorial Board
Editorial Board Open
View article: Total and bioavailable 25-hydroxyvitamin D is not associated with improved sexual dysfunction following vitamin D supplementation in women with polycystic ovarian syndrome: a pilot study
Total and bioavailable 25-hydroxyvitamin D is not associated with improved sexual dysfunction following vitamin D supplementation in women with polycystic ovarian syndrome: a pilot study Open
Background Vitamin D (Vit D) deficiency has been linked to symptoms of polycystic ovary syndrome (PCOS), yet little is known about Vit D supplementation as a treatment for sexual dysfunction (SDy) in women with PCOS. Aim To explore the imp…
View article: Urinary Androgens Provide Additional Evidence Related to Metabolism and Are Correlated With Serum Androgens in Girls
Urinary Androgens Provide Additional Evidence Related to Metabolism and Are Correlated With Serum Androgens in Girls Open
Context Androgen levels are generally measured in serum samples, but urine may be a more feasible option, especially in children, as it is a noninvasive alternative. Objective To assess the correlations of 10 urinary androgen metabolites w…
View article: Comparison of estrogenic components used for hormonal contraception
Comparison of estrogenic components used for hormonal contraception Open
Attempts have been made over the years to replace ethinyl estradiol (EE) in combined oral contraceptives (COCs) with the less potent natural estrogen estradiol (E2), or its prodrug, E2 valerate (E2V), to im…
View article: Comparative estrogen exposure from compounded transdermal estradiol creams and Food and Drug Administration-approved transdermal estradiol gels and patches
Comparative estrogen exposure from compounded transdermal estradiol creams and Food and Drug Administration-approved transdermal estradiol gels and patches Open
Objective The aim of this study was to evaluate the amount of estrogen exposure associated with the use of compounded transdermal estradiol (E2) creams and compare it with estrogen exposure associated with the use of Food and Drug Administ…
View article: Anti-Müllerian hormone levels are associated with skeletal maturity in adolescent girls in the Fels Longitudinal Study
Anti-Müllerian hormone levels are associated with skeletal maturity in adolescent girls in the Fels Longitudinal Study Open
The role of anti-Müllerian hormone (AMH), a potential marker of the hypothalamic-pituitary-ovarian axis, is not well established in adolescent females. Most studies use secondary sexual characteristics or chronological age as predictors fo…
View article: Neuroendocrine, neurotransmitter, and gut microbiota imbalance contributing to potential psychiatric disorder prevalence in polycystic ovarian syndrome
Neuroendocrine, neurotransmitter, and gut microbiota imbalance contributing to potential psychiatric disorder prevalence in polycystic ovarian syndrome Open
Polycystic ovarian syndrome (PCOS) is the most common endocrine disorder in women, affecting up to 15% of reproductive-aged women. Polycystic ovarian syndrome is a heterogeneous disorder, both in the sense that many different factors may p…
View article: Progesterone from ovulatory menstrual cycles is an important cause of breast cancer
Progesterone from ovulatory menstrual cycles is an important cause of breast cancer Open
Many factors, including reproductive hormones, have been linked to a woman’s risk of developing breast cancer (BC). We reviewed the literature regarding the relationship between ovulatory menstrual cycles (MCs) and BC risk. Physiological v…
View article: The association of hysterectomy with or without ovarian conservation with subclinical atherosclerosis progression in healthy postmenopausal women
The association of hysterectomy with or without ovarian conservation with subclinical atherosclerosis progression in healthy postmenopausal women Open
Objective While the deleterious associations of surgical menopause after bilateral oophorectomy with cardiovascular disease are documented, less is specifically known concerning subclinical atherosclerosis progression. Methods We used data…
View article: Supplementary Table 4 from Relationships between Circulating and Intraprostatic Sex Steroid Hormone Concentrations
Supplementary Table 4 from Relationships between Circulating and Intraprostatic Sex Steroid Hormone Concentrations Open
Supplementary Table 4: Multivariable Linear Regressions between Log Continous Serum and Tissue Hormones Stratified by Race
View article: Supplementary Table 1 from Relationships between Circulating and Intraprostatic Sex Steroid Hormone Concentrations
Supplementary Table 1 from Relationships between Circulating and Intraprostatic Sex Steroid Hormone Concentrations Open
Supplementary Table 1: Reproducibility of serum and tissue hormone assays used for the main analysis
View article: Supplementary Table 1 from Relationships between Circulating and Intraprostatic Sex Steroid Hormone Concentrations
Supplementary Table 1 from Relationships between Circulating and Intraprostatic Sex Steroid Hormone Concentrations Open
Supplementary Table 1: Reproducibility of serum and tissue hormone assays used for the main analysis
View article: Supplementary Table 3 from Relationships between Circulating and Intraprostatic Sex Steroid Hormone Concentrations
Supplementary Table 3 from Relationships between Circulating and Intraprostatic Sex Steroid Hormone Concentrations Open
Supplementary Table 3: Multivariable Linear Regressions between Log Continous Serum and Tissue Hormones Stratified by Gleason Score
View article: Supplementary Table 1 from Endogenous Sex Hormones and Breast Density in Young Women
Supplementary Table 1 from Endogenous Sex Hormones and Breast Density in Young Women Open
Supplementary Table 1. Adjusted geometric mean and 95% confidence interval (CI) for percent dense breast volume, absolute dense breast volume, and absolute non-dense breast volume by quartiles of test
View article: Supplementary Table 2 from Relationships between Circulating and Intraprostatic Sex Steroid Hormone Concentrations
Supplementary Table 2 from Relationships between Circulating and Intraprostatic Sex Steroid Hormone Concentrations Open
Supplementary Table 2: Reproducibility of average tissue hormone assays by zone and overall from a pilot study of 30 men recruited at George Washington University Medical Center that included a total of 171 prostate biopsies.
View article: Supplementary Table 4 from Relationships between Circulating and Intraprostatic Sex Steroid Hormone Concentrations
Supplementary Table 4 from Relationships between Circulating and Intraprostatic Sex Steroid Hormone Concentrations Open
Supplementary Table 4: Multivariable Linear Regressions between Log Continous Serum and Tissue Hormones Stratified by Race
View article: Data from Endogenous Sex Hormones and Breast Density in Young Women
Data from Endogenous Sex Hormones and Breast Density in Young Women Open
Background: Breast density is a strong risk factor for breast cancer and reflects epithelial and stromal content. Breast tissue is particularly sensitive to hormonal stimuli before it fully differentiates following the first full-te…
View article: Supplementary Table 5 from Relationships between Circulating and Intraprostatic Sex Steroid Hormone Concentrations
Supplementary Table 5 from Relationships between Circulating and Intraprostatic Sex Steroid Hormone Concentrations Open
Supplementary Table 5: Multivariable Linear Regressions between Log Continous Serum and Tissue Hormones Stratified by Median Age at Blood Draw
View article: Data from Relationships between Circulating and Intraprostatic Sex Steroid Hormone Concentrations
Data from Relationships between Circulating and Intraprostatic Sex Steroid Hormone Concentrations Open
Background: Sex hormones have been implicated in prostate carcinogenesis, yet epidemiologic studies have not provided substantiating evidence. We tested the hypothesis that circulating concentrations of sex steroid hormones reflect …
View article: Data from Endogenous Sex Hormones and Breast Density in Young Women
Data from Endogenous Sex Hormones and Breast Density in Young Women Open
Background: Breast density is a strong risk factor for breast cancer and reflects epithelial and stromal content. Breast tissue is particularly sensitive to hormonal stimuli before it fully differentiates following the first full-te…