Franziska Sick
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View article: A nanoluciferase-tagged Schmallenberg virus (SBV): an efficient tool for measuring and tracking viral infection dynamics
A nanoluciferase-tagged Schmallenberg virus (SBV): an efficient tool for measuring and tracking viral infection dynamics Open
Introduction. Schmallenberg virus (SBV) is an arthropod-borne virus and belongs to the Simbu serogroup within the family Peribunyaviridae , genus Orthobunyavirus . Infection of naïve ruminants at critical stages of gestation can result in …
View article: Schmallenberg virus non-structural proteins NSs and NSm are not essential for experimental infection of <i>Culicoides sonorensis</i> biting midges
Schmallenberg virus non-structural proteins NSs and NSm are not essential for experimental infection of <i>Culicoides sonorensis</i> biting midges Open
The teratogenic orthobunyavirus Schmallenberg virus (SBV) is transmitted between its mammalian hosts by Culicoides biting midges. The genome of circulating SBV, i.e., variants present in viremic ruminants or insect vectors, is very stable,…
View article: Experimental BTV-3 and BTV-8 infection of<i>Culicoides sonorensis</i>biting midges
Experimental BTV-3 and BTV-8 infection of<i>Culicoides sonorensis</i>biting midges Open
BTV-3 emerged in the Netherlands in 2023 and spread rapidly to neighboring countries. Compared to the BTV-8 outbreak in 2006, the course of the BTV-3 epizootic is more severe. Experimental infection of laboratory-reared Culicoides sonorens…
View article: Schmallenberg virus non-structural proteins NSs and NSm are not essential for experimental infection of<i>Culicoides sonorensis</i>biting midges
Schmallenberg virus non-structural proteins NSs and NSm are not essential for experimental infection of<i>Culicoides sonorensis</i>biting midges Open
The teratogenic orthobunyavirus Schmallenberg virus (SBV) is transmitted between its mammalian hosts by Culicoides biting midges. The genome of circulating SBV, i.e. variants present in viraemic ruminants or insect vectors, is very stable,…
View article: Bluetongue Virus Serotype 3 and Schmallenberg Virus in <i>Culicoides</i> Biting Midges, Western Germany, 2023
Bluetongue Virus Serotype 3 and Schmallenberg Virus in <i>Culicoides</i> Biting Midges, Western Germany, 2023 Open
In October 2023, bluetongue virus serotype 3 (BTV-3) emerged in Germany, where Schmallenberg virus is enzootic. We detected BTV-3 in 1 pool of Culicoides biting midges collected at the time ruminant infections were reported. Schmallenberg …
View article: Emergence of bluetongue virus serotype 3 in western Germany, October 2023, and<i>ad-hoc</i>monitoring in<i>Culicoides</i>biting midges
Emergence of bluetongue virus serotype 3 in western Germany, October 2023, and<i>ad-hoc</i>monitoring in<i>Culicoides</i>biting midges Open
Bluetongue virus serotype 3 emerged in October 2023 in Germany, where Schmallenberg virus is enzootic. BTV-3 was detected in a pool of Culicoides biting midges at the same time as infections were reported from ruminants. Schmallenberg viru…
View article: CVnCoV protects human ACE2 transgenic mice from ancestral B BavPat1 and emerging B.1.351 SARS-CoV-2
CVnCoV protects human ACE2 transgenic mice from ancestral B BavPat1 and emerging B.1.351 SARS-CoV-2 Open
The ongoing severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) pandemic necessitates the fast development of vaccines as the primary control option. Recently, viral mutants termed “variants of concern” (VOC) have emerged with the…
View article: Differentiation of Antibodies against Selected Simbu Serogroup Viruses by a Glycoprotein Gc-Based Triplex ELISA
Differentiation of Antibodies against Selected Simbu Serogroup Viruses by a Glycoprotein Gc-Based Triplex ELISA Open
The Simbu serogroup of orthobunyaviruses includes several pathogens of veterinary importance, among them Schmallenberg virus (SBV), Akabane virus (AKAV) and Shuni virus (SHUV). They infect predominantly ruminants and induce severe congenit…
View article: Shuni virus‐induced meningoencephalitis after experimental infection of cattle
Shuni virus‐induced meningoencephalitis after experimental infection of cattle Open
Shuni virus (SHUV), an insect-transmitted orthobunyavirus of the Simbu serogroup within the family Peribunyaviridae, may induce severe congenital malformations when naïve ruminants are infected during gestation. Only recently, another clin…
View article: Culicoides Biting Midges—Underestimated Vectors for Arboviruses of Public Health and Veterinary Importance
Culicoides Biting Midges—Underestimated Vectors for Arboviruses of Public Health and Veterinary Importance Open
Culicoides biting midges, small hematophagous dipterans, are the demonstrated or putative vectors of multiple arboviruses of veterinary and public health importance. Despite its relevance in disease spread, the ceratopogonid genus Culicoid…