Frédéric Austerlitz
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View article: Methods for inferring coalescent tree topologies from genomic data: a comparison based on the transmission of reproductive success
Methods for inferring coalescent tree topologies from genomic data: a comparison based on the transmission of reproductive success Open
iInferring coalescent trees from genomic data has become a major subject in population genetics, particularly with the recent advances in tree sequence reconstruction methods. Yet, how well these methods perform under imbalanced genealogie…
View article: Assessing simulation-based supervised machine learning for demographic parameter inference from genomic data
Assessing simulation-based supervised machine learning for demographic parameter inference from genomic data Open
The ever-increasing availability of high-throughput DNA sequences and the development of numerous computational methods have led to considerable advances in our understanding of the evolutionary and demographic history of populations. Seve…
View article: Cultural transmission of reproductive success impacts genomic diversity, coalescent tree topologies, and demographic inferences
Cultural transmission of reproductive success impacts genomic diversity, coalescent tree topologies, and demographic inferences Open
Cultural transmission of reproductive success has been observed in many human populations as well as other animals. Cultural transmission of reproductive success consists of a positive correlation of nongenetic origin between the progeny s…
View article: Inferring linguistic transmission between generations at the scale of individuals
Inferring linguistic transmission between generations at the scale of individuals Open
Historical linguistics strongly benefited from recent methodological advances inspired by phylogenetics. Nevertheless, no available method uses contemporaneous within-population linguistic diversity to reconstruct the history of human popu…
View article: Cultural transmission of reproductive success impacts genomic diversity, coalescent tree topologies and demographic inferences
Cultural transmission of reproductive success impacts genomic diversity, coalescent tree topologies and demographic inferences Open
Cultural Transmission of Reproductive Success (CTRS) has been observed in many human populations as well as other animals. It consists in a positive correlation of non-genetic origin between the progeny size of parents and children. This c…
View article: No evidence for female kin association, indications for extragroup paternity, and sex‐biased dispersal patterns in wild western gorillas
No evidence for female kin association, indications for extragroup paternity, and sex‐biased dispersal patterns in wild western gorillas Open
Characterizing animal dispersal patterns and the rational behind individuals’ transfer choices is a long‐standing question of interest in evolutionary biology. In wild western gorillas ( Gorilla gorilla ), a one‐male polygynous species, pr…
View article: Polygenic Adaptation: Integrating Population Genetics and Gene Regulatory Networks
Polygenic Adaptation: Integrating Population Genetics and Gene Regulatory Networks Open
The adaptation of populations to local environments often relies on the selection of optimal values for polygenic traits. Here, we first summarize the results obtained from different quantitative genetics and population genetics models, ab…
View article: A method to estimate effective population size from linkage disequilibrium when generations overlap
A method to estimate effective population size from linkage disequilibrium when generations overlap Open
Effective population size ( N e ) is a key parameter in evolutionary and conservation studies. It represents the number of individuals of an ideal panmictic population that would have the same genetic drift as the observed population and c…
View article: Sharing and reporting benefits from biodiversity research
Sharing and reporting benefits from biodiversity research Open
The most remarkable feature of our planet is the diversity of its life forms, ranging from viruses and nanobacteria to blue whales and giant sequoias to satanic leaf‐tailed geckos and leafy seadragons (look them up!). Life is found in esse…
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social, economic, and ethical challenges faced in our business and which are important to our diverse stakeholder groups.
View article: Sahelian pastoralism from the perspective of variants associated with lactase persistence
Sahelian pastoralism from the perspective of variants associated with lactase persistence Open
Objectives Archeological evidence shows that first nomadic pastoralists came to the African Sahel from northeastern Sahara, where milking is reported by ~7.5 ka. A second wave of pastoralists arrived with the expansion of Arabic tribes in …
View article: New insights on spatial genetic structure and diversity of Coffea canephora (Rubiaceae) in Upper Guinea based on old herbaria
New insights on spatial genetic structure and diversity of Coffea canephora (Rubiaceae) in Upper Guinea based on old herbaria Open
Backgrounds and aims – Previous studies showed that robusta coffee (Coffea canephora Pierre ex A.Froehner), one of the two cultivated coffee species worldwide, can be classified in two genetic groups: the Guinean group originating in Upper…
View article: The Genetic Architecture of Chronic Mountain Sickness in Peru
The Genetic Architecture of Chronic Mountain Sickness in Peru Open
Chronic mountain sickness (CMS) is a pathological condition resulting from chronic exposure to high-altitude hypoxia. While its prevalence is high in native Andeans (>10%), little is known about the genetic architecture of this disease. He…
View article: An ABC Method for Whole-Genome Sequence Data: Inferring Paleolithic and Neolithic Human Expansions
An ABC Method for Whole-Genome Sequence Data: Inferring Paleolithic and Neolithic Human Expansions Open
Species generally undergo a complex demographic history consisting, in particular, of multiple changes in population size. Genome-wide sequencing data are potentially highly informative for reconstructing this demographic history. A crucia…
View article: An evaluation of the methods to estimate effective population size from measures of linkage disequilibrium
An evaluation of the methods to estimate effective population size from measures of linkage disequilibrium Open
In 1971, John Sved derived an approximate relationship between linkage disequilibrium (LD) and effective population size for an ideal finite population. This seminal work was extended by Sved and Feldman (Theor Pop Biol 4, 129, 1973) and W…
View article: Inferring linguistic transmission between generations at the scale of individuals
Inferring linguistic transmission between generations at the scale of individuals Open
Historical linguistics strongly benefited from recent methodological advances inspired by phylogenetics. Nevertheless, no available method uses contemporaneous within-population linguistic diversity to reconstruct the history of human popu…
View article: An ABC method for whole-genome sequence data: inferring paleolithic and neolithic human expansions
An ABC method for whole-genome sequence data: inferring paleolithic and neolithic human expansions Open
Species generally undergo a complex demographic history, consisting, in particular, of multiple changes in population size. Genome-wide sequencing data are potentially highly informative for reconstructing this demographic history. A cruci…
View article: Neutral Theory: From Complex Population History to Natural Selection and Sociocultural Phenomena in Human Populations
Neutral Theory: From Complex Population History to Natural Selection and Sociocultural Phenomena in Human Populations Open
Here, we present a synthetic view on how Kimura's Neutral theory has helped us gaining insight on the different evolutionary forces that shape human evolution. We put this perspective in the frame of recent emerging challenges: the use of …
View article: Population networks from DNA sequences: methodological developments
Population networks from DNA sequences: methodological developments Open
Several classes of methods have been proposed for inferring the history of populations from genetic polymorphism data. As connectivity is a key factor to explain the structure of populations, several graph-based methods have been developed…
View article: Genetic and linguistic histories in Central Asia inferred using approximate Bayesian computations
Genetic and linguistic histories in Central Asia inferred using approximate Bayesian computations Open
Linguistic and genetic data have been widely compared, but the histories underlying these descriptions are rarely jointly inferred. We developed a unique methodological framework for analysing jointly language diversity and genetic polymor…
View article: Supplementary material from "Genetic and linguistic histories in Central Asia inferred using approximate Bayesian computations"
Supplementary material from "Genetic and linguistic histories in Central Asia inferred using approximate Bayesian computations" Open
Linguistic and genetic data have been widely compared, but the histories underlying these descriptions are rarely jointly inferred. We developed a unique methodological framework for analysing jointly language diversity and genetic polymor…
View article: Inferring Population Size History from Large Samples of Genome-Wide Molecular Data - An Approximate Bayesian Computation Approach
Inferring Population Size History from Large Samples of Genome-Wide Molecular Data - An Approximate Bayesian Computation Approach Open
Inferring the ancestral dynamics of effective population size is a long-standing question in population genetics, which can now be tackled much more accurately thanks to the massive genomic data available in many species. Several promising…
View article: Inferring population size history from large samples of genome wide molecular data - an approximate Bayesian computation approach
Inferring population size history from large samples of genome wide molecular data - an approximate Bayesian computation approach Open
Inferring the ancestral dynamics of effective population size is a long-standing question in population genetics, which can now be tackled much more accurately thanks to the massive genomic data available in many species. Several promising…