Frédéric Boisson
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View article: Hetero-Diels–Alder and CuAAC Click Reactions for Fluorine-18 Labeling of Peptides: Automation and Comparative Study of the Two Methods
Hetero-Diels–Alder and CuAAC Click Reactions for Fluorine-18 Labeling of Peptides: Automation and Comparative Study of the Two Methods Open
Radiolabeled peptides are valuable tools for diagnosis or therapies; they are often radiofluorinated using an indirect approach based on an F-18 prosthetic group. Herein, we are reporting our results on the F-18 radiolabeling of three pept…
View article: Experimental Uses of Positronium and Potential for Biological Applications
Experimental Uses of Positronium and Potential for Biological Applications Open
International audience
View article: Catalyst-free thia-Diels-Alder click reaction for the labeling of peptides for imaging applications
Catalyst-free thia-Diels-Alder click reaction for the labeling of peptides for imaging applications Open
International audience
View article: Imaging Capabilities of the IRIS and IRIS XL-260 PET/CT Systems for High-Throughput Imaging: A Quantification Cross-Validation Study
Imaging Capabilities of the IRIS and IRIS XL-260 PET/CT Systems for High-Throughput Imaging: A Quantification Cross-Validation Study Open
International audience
View article: 64CuCl2 PET Imaging of 4T1-Related Allograft of Triple-Negative Breast Cancer in Mice
64CuCl2 PET Imaging of 4T1-Related Allograft of Triple-Negative Breast Cancer in Mice Open
64CuCl2 is an economic radiotracer for oncologic PET investigations. In the present study, we characterized the uptake of 64CuCl2 in vivo by µPET/CT in an allograft 4T1-related mouse model (BALB/c) of advanced breast cancer. 18F-FDG was us…
View article: Evaluation of Monte-Carlo-based System Response Matrix Completeness and its Impact on Image Quality in Positron Emission Tomography
Evaluation of Monte-Carlo-based System Response Matrix Completeness and its Impact on Image Quality in Positron Emission Tomography Open
A major strength of iterative algorithms used in positron emission tomography (PET) lies in their abilities to introduce precise models of the physics at play, which includes the statistical nature of the detection processes, and a detaile…
View article: Hetero-Diels–Alder click reaction of dithioesters for a catalyst-free indirect <sup>18</sup>F-radiolabelling of peptides
Hetero-Diels–Alder click reaction of dithioesters for a catalyst-free indirect <sup>18</sup>F-radiolabelling of peptides Open
The hetero-Diels–Alder reaction involving a dithioester and a radiofluorinated diene as a novel prosthetic group was used as a catalyst-free click-reaction for the indirect 18 F-labelling of peptides and applied to a PSMA-ligand for in viv…
View article: F autoradiography with the Mimosa-28: Characterisation and Application
F autoradiography with the Mimosa-28: Characterisation and Application Open
International audience
View article: Effect of Carbidopa on <sup>18</sup>F-FDOPA Uptake in Insulinoma: From Cell Culture to Small-Animal PET Imaging
Effect of Carbidopa on <sup>18</sup>F-FDOPA Uptake in Insulinoma: From Cell Culture to Small-Animal PET Imaging Open
Carbidopa did not influence in vitro 18F-FDOPA accumulation in RIN-m5F cells but improved insulinoma imaging in vivo. Our findings increase current knowledge about the 18F-FDOPA uptake profile of RIN-m5F cells and a related xenograft model…