Frédéric Briend
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View article: Predictors of Psychotropic Medication Use Among Autistic Adults
Predictors of Psychotropic Medication Use Among Autistic Adults Open
Purpose No psychotropic treatment has recognized effects on the core clinical signs of autism. In this retrospective study, we sought to identify predictors of psychotropic medication in autistic adults among demographic, diagnostic and fu…
View article: Autonomic Disequilibrium at Rest in Autistic Children and Adults
Autonomic Disequilibrium at Rest in Autistic Children and Adults Open
Autism Spectrum Disorder (ASD) symptoms have been proposed to be linked to Autonomic Nervous System (ANS) atypical functioning, in particular sympathetic hyper-arousal and parasympathetic under-activation. The objective of this study was t…
View article: A Compressive Armchair (OTO) to Perform Deep Pressure Therapy in Children With Autism Spectrum Disorder: User-Centered Design and Feasibility Study
A Compressive Armchair (OTO) to Perform Deep Pressure Therapy in Children With Autism Spectrum Disorder: User-Centered Design and Feasibility Study Open
Background Deep pressure therapy (DPT) is widely used to reduce anxiety in children with autism spectrum disorder (ASD), but evidence of its efficacy is limited. Objective This study aims to design a usable, nonstigmatizing compressive arm…
View article: A Compressive Armchair (OTO) to Perform Deep Pressure Therapy in Children With Autism Spectrum Disorder: User-Centered Design and Feasibility Study (Preprint)
A Compressive Armchair (OTO) to Perform Deep Pressure Therapy in Children With Autism Spectrum Disorder: User-Centered Design and Feasibility Study (Preprint) Open
BACKGROUND Deep pressure therapy (DPT) is widely used to reduce anxiety in children with autism spectrum disorder (ASD), but evidence of its efficacy is limited. OBJECTIVE This study aims to design a usable, nonstigmatizing compressive …
View article: Autonomic disequilibrium at rest in autistic children and adults
Autonomic disequilibrium at rest in autistic children and adults Open
Autism Spectrum Disorders (ASD) symptoms have been proposed to be linked to Autonomic Nervous System (ANS) dysfunctions, in particular sympathetic hyper-arousal and parasympathetic under-activation. The objective of this study was to chara…
View article: Voice acoustics allow classifying autism spectrum disorder with high accuracy
Voice acoustics allow classifying autism spectrum disorder with high accuracy Open
Early identification of children on the autism spectrum is crucial for early intervention with long-term positive effects on symptoms and skills. The need for improved objective autism detection tools is emphasized by the poor diagnostic p…
View article: Impact of adapted physical activity on hippocampal N-Acetyl Aspartate in patients with schizophrenia
Impact of adapted physical activity on hippocampal N-Acetyl Aspartate in patients with schizophrenia Open
Introduction Adapted physical activity (APA) has beneficial neurobiological impact but the underlying pathophysiological mechanisms remain poorly described. APA is currently recognized as an adjuvant therapy to antipsychotic treatments in …
View article: Voice acoustics allow classifying autism spectrum disorder with high accuracy.
Voice acoustics allow classifying autism spectrum disorder with high accuracy. Open
Early identification of children on the autism spectrum is crucial for early intervention with long-term positive effects on symptoms and skills. The need for improved objective autism detection tools is emphasized by the poor diagnostic p…
View article: White Matter Neurometabolic Signatures Support the Deficit and Nondeficit Distinction in Antipsychotic-Naïve First-Episode Psychosis Patients
White Matter Neurometabolic Signatures Support the Deficit and Nondeficit Distinction in Antipsychotic-Naïve First-Episode Psychosis Patients Open
The deficit syndrome is thought to be a more homogenous clinical subgroup within the syndrome of schizophrenia that is characterized by enduring negative symptoms. It is hypothesized that distinct pathophysiological processes underlie the …
View article: Hippocampal glutamate and hippocampus subfield volumes in antipsychotic-naive first episode psychosis subjects and relationships to duration of untreated psychosis
Hippocampal glutamate and hippocampus subfield volumes in antipsychotic-naive first episode psychosis subjects and relationships to duration of untreated psychosis Open
Evidence points toward a relationship between longer duration of untreated psychosis (DUP) and worse long-term outcomes in patients with first episode psychosis (FEP), but the underlying neurobiology remains poorly understood. Proton magne…
View article: Aberrant static and dynamic functional patterns of frontoparietal control network in antipsychotic‐naïve first‐episode psychosis subjects
Aberrant static and dynamic functional patterns of frontoparietal control network in antipsychotic‐naïve first‐episode psychosis subjects Open
Psychotic disorders are disabling clinical syndromes characterized by widespread alterations in cortical information processing. Disruption of frontoparietal network (FPN) connectivity has emerged as a common footprint across the psychosis…
View article: O2.2. EVALUATION OF THE RELATIONSHIP BETWEEN GLUTAMATE AND BRAIN CONNECTIVITY IN ANTIPSYCHOTIC-NAïVE FIRST EPISODE PATIENTS – A COMBINED MAGNETIC RESONANCE SPECTROSCOPY AND RESTING STATE FUNCTIONAL CONNECTIVITY MRI STUDY
O2.2. EVALUATION OF THE RELATIONSHIP BETWEEN GLUTAMATE AND BRAIN CONNECTIVITY IN ANTIPSYCHOTIC-NAïVE FIRST EPISODE PATIENTS – A COMBINED MAGNETIC RESONANCE SPECTROSCOPY AND RESTING STATE FUNCTIONAL CONNECTIVITY MRI STUDY Open
Background Schizophrenia is thought to be a disorder of brain dysconnectivity. An imbalance between cortical excitation/inhibition is also implicated, but the link between these abnormalities remains unclear. The present study used resting…
View article: T89. LONGITUDINAL EVALUATION OF GLUTAMATE AND N-ACETYL-ASPARTATE IN ANTIPSYCHOTIC-NAïVE FIRST EPISODE PSYCHOSIS SUBJECTS AND RELATIONSHIPS TO DURATION OF UNTREATED PSYCHOSIS AND RESPONSE TO ANTIPSYCHOTIC MEDICATION
T89. LONGITUDINAL EVALUATION OF GLUTAMATE AND N-ACETYL-ASPARTATE IN ANTIPSYCHOTIC-NAïVE FIRST EPISODE PSYCHOSIS SUBJECTS AND RELATIONSHIPS TO DURATION OF UNTREATED PSYCHOSIS AND RESPONSE TO ANTIPSYCHOTIC MEDICATION Open
Meta-analyses have consistently identified a relationship between longer duration of untreated psychosis (DUP) and worse long-term outcomes in patients with schizophrenia. However, the neurobiology of this phenomenon and its implications f…