Frédéric Preitner
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View article: CDK4 deletion in mice prevents fat accumulation and increases endurance capacity through activation of estrogen-related receptor (ERR)-driven oxidative metabolism in skeletal muscle
CDK4 deletion in mice prevents fat accumulation and increases endurance capacity through activation of estrogen-related receptor (ERR)-driven oxidative metabolism in skeletal muscle Open
Cyclin-dependent kinase 4 (CDK4) canonical role is to control cell cycle progression from G1 to S phases. However, recent studies reported that CDK4 regulates energy metabolism in non-proliferating cells such as hepatocytes or adipocytes. …
View article: Depriving Mice of Sleep also Deprives of Food
Depriving Mice of Sleep also Deprives of Food Open
Both sleep-wake behavior and circadian rhythms are tightly coupled to energy metabolism and food intake. Altered feeding times in mice are known to entrain clock gene rhythms in the brain and liver, and sleep-deprived humans tend to eat mo…
View article: Depriving mice of sleep also deprives of food
Depriving mice of sleep also deprives of food Open
Both sleep-wake behavior and circadian rhythms are tightly coupled to energy metabolism and food intake. Altered feeding times in mice are known to entrain clock-gene rhythms in brain and liver and sleep-deprived humans tend to eat more an…
View article: Chronic Stress Potentiates High Fructose–Induced Lipogenesis in Rat Liver and Kidney
Chronic Stress Potentiates High Fructose–Induced Lipogenesis in Rat Liver and Kidney Open
Scope Intake of fructose‐sweetened beverages and chronic stress (CS) both increase risk of cardiometabolic diseases. The aim is to investigate whether these factors synergistically perturb lipid metabolism in rat liver and kidney. Methods …
View article: Systemic PPARγ deletion in mice provokes lipoatrophy, organomegaly, severe type 2 diabetes and metabolic inflexibility
Systemic PPARγ deletion in mice provokes lipoatrophy, organomegaly, severe type 2 diabetes and metabolic inflexibility Open
View article: OP0358 Why do not all chronic kidney disease patients get gout? impaired neutrophil chemotaxis in hyperuricemia-related ckd
OP0358 Why do not all chronic kidney disease patients get gout? impaired neutrophil chemotaxis in hyperuricemia-related ckd Open
View article: Modulation of hepatic inflammation and energy-sensing pathways in the rat liver by high-fructose diet and chronic stress
Modulation of hepatic inflammation and energy-sensing pathways in the rat liver by high-fructose diet and chronic stress Open
View article: Involvement of glucocorticoid prereceptor metabolism and signaling in rat visceral adipose tissue lipid metabolism after chronic stress combined with high-fructose diet
Involvement of glucocorticoid prereceptor metabolism and signaling in rat visceral adipose tissue lipid metabolism after chronic stress combined with high-fructose diet Open
View article: Glucose transporter 2 mediates the hypoglycemia-induced increase in cerebral blood flow
Glucose transporter 2 mediates the hypoglycemia-induced increase in cerebral blood flow Open
Glucose transporter 2 ( Glut2)-positive cells are sparsely distributed in brain and play an important role in the stimulation of glucagon secretion in response to hypoglycemia. We aimed to determine if Glut2-positive cells can influence an…
View article: Glutamate Cysteine Ligase—Modulatory Subunit Knockout Mouse Shows Normal Insulin Sensitivity but Reduced Liver Glycogen Storage
Glutamate Cysteine Ligase—Modulatory Subunit Knockout Mouse Shows Normal Insulin Sensitivity but Reduced Liver Glycogen Storage Open
Glutathione (GSH) deficits have been observed in several mental or degenerative illness, and so has the metabolic syndrome. The impact of a decreased glucose metabolism on the GSH system is well-known, but the effect of decreased GSH level…
View article: Biological Characterization of Gene Response to Insulin-Induced Hypoglycemia in Mouse Retina
Biological Characterization of Gene Response to Insulin-Induced Hypoglycemia in Mouse Retina Open
Glucose is the most important metabolic substrate of the retina and maintenance of normoglycemia is an essential challenge for diabetic patients. Chronic, exaggerated, glycemic excursions could lead to cardiovascular diseases, nephropathy,…
View article: Sets of primers used for qRT-PCR of genes involved in lipid metabolism.
Sets of primers used for qRT-PCR of genes involved in lipid metabolism. Open
View article: Loss of the RNA polymerase III repressor MAF1 confers obesity resistance
Loss of the RNA polymerase III repressor MAF1 confers obesity resistance Open
MAF1 is a global repressor of RNA polymerase III transcription that regulates the expression of highly abundant noncoding RNAs in response to nutrient availability and cellular stress. Thus, MAF1 function is thought to be important for met…
View article: A Neuron-Specific Deletion of the MicroRNA-Processing Enzyme DICER Induces Severe but Transient Obesity in Mice
A Neuron-Specific Deletion of the MicroRNA-Processing Enzyme DICER Induces Severe but Transient Obesity in Mice Open
MicroRNAs (miRNAs) are small, non-coding RNA molecules that regulate gene expression post-transcriptionally. MiRNAs are implicated in various biological processes associated with obesity, including adipocyte differentiation and lipid metab…
View article: No development of hypertension in the hyperuricemic liver-Glut9 knockout mouse
No development of hypertension in the hyperuricemic liver-Glut9 knockout mouse Open