Frederick Lanni
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View article: Roles of P-body factors in Candida albicans filamentation and stress response
Roles of P-body factors in Candida albicans filamentation and stress response Open
Hyphal growth is strongly associated with virulence in the human fungal pathogen Candida albicans . While hyphal transcriptional networks have been the subject of intense study, relatively little is known about post-transcriptional regulat…
View article: Roles of P-body factors in <i>Candida albicans</i> filamentation and stress response
Roles of P-body factors in <i>Candida albicans</i> filamentation and stress response Open
Hyphal growth is strongly associated with virulence in the human fungal pathogen Candida albicans . While hyphal transcriptional networks have been the subject of intense study, relatively little is known about post-transcriptional regulat…
View article: Biofilm-associated metabolism via ERG251 in Candida albicans
Biofilm-associated metabolism via ERG251 in Candida albicans Open
Biofilm formation by the fungal pathogen Candida albicans is the basis for its ability to infect medical devices. The metabolic gene ERG251 has been identified as a target of biofilm transcriptional regulator Efg1, and here we report that …
View article: Hgc1 Independence of Biofilm Hyphae in Candida albicans
Hgc1 Independence of Biofilm Hyphae in Candida albicans Open
The HGC1 gene encodes a cyclin that is required for virulence of the fungal pathogen Candida albicans . It is required to produce the elongated hyphal filaments of free-living planktonic cells that are associated with virulence.
View article: In Situ Volumetric Imaging and Analysis of FRESH 3D Bioprinted Constructs Using Optical Coherence Tomography (Data and 3D models)
In Situ Volumetric Imaging and Analysis of FRESH 3D Bioprinted Constructs Using Optical Coherence Tomography (Data and 3D models) Open
These files contain 3D models and reconstructions of the 3D printed models after OCT imaging of the brain stem, circle of willis, kidney, vestibular apparatus, mixing network, and resolution text. These are from the journal article "In Sit…
View article: In Situ Volumetric Imaging and Analysis of FRESH 3D Bioprinted Constructs Using Optical Coherence Tomography (Data and 3D models)
In Situ Volumetric Imaging and Analysis of FRESH 3D Bioprinted Constructs Using Optical Coherence Tomography (Data and 3D models) Open
These files contain 3D models and reconstructions of the 3D printed models after OCT imaging of the brain stem, circle of willis, kidney, vestibular apparatus, mixing network, and resolution text. These are from the journal article "In Sit…
View article: In Situ Volumetric Imaging and Analysis of FRESH 3D Bioprinted Constructs Using Optical Coherence Tomography
In Situ Volumetric Imaging and Analysis of FRESH 3D Bioprinted Constructs Using Optical Coherence Tomography Open
As 3D bioprinting has grown as a fabrication technology, so too has the need for improved analytical methods to characterize these engineered constructs. This is especially challenging for soft tissues composed of hydrogels and cells as th…
View article: Internet-Based Image Analysis Quantifies Contractile Behavior of Individual Fibroblasts inside Model Tissue
Internet-Based Image Analysis Quantifies Contractile Behavior of Individual Fibroblasts inside Model Tissue Open
In a cell-populated collagen gel, intrinsic fiber structure visible in differential interference contrast images can provide markers for an in situ strain gauge to quantify cell-gel mechanics, while optical sections of fluorescent protein …
View article: Clarifying and Imaging <em>Candida albicans</em> Biofilms
Clarifying and Imaging <em>Candida albicans</em> Biofilms Open
The microbial fungus Candida albicans can undergo a change from commensal colonization to virulence that is strongly correlated with its ability to switch from yeast-form growth to hyphal growth. Cells initiating this process become adhere…
View article: Bypass of Candida albicans Filamentation/Biofilm Regulators through Diminished Expression of Protein Kinase Cak1
Bypass of Candida albicans Filamentation/Biofilm Regulators through Diminished Expression of Protein Kinase Cak1 Open
Biofilm formation on implanted medical devices is a major source of lethal invasive infection by Candida albicans. Filamentous growth of this fungus is tied to biofilm formation because many filamentation-associated genes are required for …
View article: Coordination of Candida albicans Invasion and Infection Functions by Phosphoglycerol Phosphatase Rhr2
Coordination of Candida albicans Invasion and Infection Functions by Phosphoglycerol Phosphatase Rhr2 Open
The Candida albicans RHR2 gene, which specifies a glycerol biosynthetic enzyme, is required for biofilm formation in vitro and in vivo. Prior studies indicate that RHR2 is ultimately required for expression of adhesin genes, such as ALS1. …