Frederick Nitchie
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View article: Neuroimaging changes in major depression with brief computer-assisted cognitive behavioral therapy compared to waitlist
Neuroimaging changes in major depression with brief computer-assisted cognitive behavioral therapy compared to waitlist Open
The goals of the current study were to determine the efficacy in major depressive disorder (MDD) of a shortened, computer-augmented cognitive behavioral therapy (CCBT) protocol and to determine brain plasticity effects following CCBT. Seve…
View article: Accelerated Intermittent Theta-Burst Stimulation and Treatment-Refractory Bipolar Depression
Accelerated Intermittent Theta-Burst Stimulation and Treatment-Refractory Bipolar Depression Open
Importance Bipolar disorder (BD) is chronic and disabling, with depression accounting for the majority of time with illness. Recent research demonstrated a transformative advance in the clinical efficacy of transcranial magnetic stimulatio…
View article: The maintenance of complex visual scenes in working memory may require activation of working memory manipulation circuits in the dlPFC: A preliminary report
The maintenance of complex visual scenes in working memory may require activation of working memory manipulation circuits in the dlPFC: A preliminary report Open
Past research has shown that the bilateral dorsolateral prefrontal cortices (dlPFC) are implicated in both emotional processing as well as cognitive processing, 1,2,3 in addition to working memory 4, 5 . Exactly how these disparate process…
View article: Interleaved TMS/fMRI shows that threat decreases dlPFC-mediated top-down regulation of emotion processing
Interleaved TMS/fMRI shows that threat decreases dlPFC-mediated top-down regulation of emotion processing Open
The dorsolateral prefrontal cortex (dlPFC) is thought to be a key site in the brain’s cognitive control network, supporting cognitive processes like attention and working memory [1–7]. There is also evidence that the dlPFC is engaged durin…
View article: Neuroticism levels in severe depression may reveal association with higher levels of intelligence
Neuroticism levels in severe depression may reveal association with higher levels of intelligence Open
The anxious-misery spectrum of disorders encompasses some of the most debilitating mental disorders that effect the population at-large. In addition, neuroticism is a trait that has been shown to correlate with higher levels of reported sy…
View article: The maintenance of complex visual scenes in working memory may require activation of working memory manipulation circuits in the dlPFC
The maintenance of complex visual scenes in working memory may require activation of working memory manipulation circuits in the dlPFC Open
Past research has shown that the bilateral dorsolateral prefrontal cortices (dlPFC) are implicated in both emotional processing as well as cognitive processing, 1,2,3 in addition to working memory 4, 5 . Exactly how these disparate process…
View article: Interleaved TMS/fMRI shows that threat decreases dlPFC-mediated top-down regulation of emotion processing
Interleaved TMS/fMRI shows that threat decreases dlPFC-mediated top-down regulation of emotion processing Open
Background The right dorsolateral prefrontal cortex (dlPFC) has been indicated to be a key region in the cognitive regulation of emotion by many previous neuromodulation and neuroimaging studies. However, there is little direct causal evid…
View article: Rates of longitudinal change in <sup>18</sup>F‐flortaucipir PET vary by brain region, cognitive impairment, and age in atypical Alzheimer's disease
Rates of longitudinal change in <sup>18</sup>F‐flortaucipir PET vary by brain region, cognitive impairment, and age in atypical Alzheimer's disease Open
Introduction Longitudinal positron emission tomography (PET) studies of tau accumulation in Alzheimer's disease (AD) have noted reduced increases or frank decreases in tau signal. We investigated how such reductions related to analytical c…