Friederike A. Arlt
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View article: Neuronal-specific antibody in patients with multiple system atrophy and progressive supranuclear palsy
Neuronal-specific antibody in patients with multiple system atrophy and progressive supranuclear palsy Open
Anti-neuronal antibodies can manifest with diverse movement disorders, including parkinsonism and ataxia, and may mimic neurodegeneration. The prevalence of neuronal-specific antibodies in atypical parkinsonism remains unclear. We examined…
View article: High affinity cross-context cellular assays reveal novel protein-protein interactions of peripheral myelin protein of 22 kDa
High affinity cross-context cellular assays reveal novel protein-protein interactions of peripheral myelin protein of 22 kDa Open
Peripheral Myelin Protein 22 (PMP22) is a tetraspan membrane protein whose altered dosage causes the most common hereditary neuropathy, Charcot-Marie-Tooth disease type 1A (CMT1A). Despite its clinical significance, the physiological funct…
View article: Anti-septin complex positive autoimmune encephalitis after severe falciparum malaria: a case report
Anti-septin complex positive autoimmune encephalitis after severe falciparum malaria: a case report Open
Background Post malaria neurologic syndrome (PMNS) is a rare complication of malaria, usually caused by Plasmodium falciparum . The clinical picture is highly variable and ranges from qualitative disturbances of consciousness and psychosis…
View article: Serum anti-NMDA receptor antibodies are linked to memory impairment 12 months after stroke
Serum anti-NMDA receptor antibodies are linked to memory impairment 12 months after stroke Open
View article: Different Patterns of Autoantibody Secretion by Peripheral Blood Mononuclear Cells in Autoimmune Nodopathies
Different Patterns of Autoantibody Secretion by Peripheral Blood Mononuclear Cells in Autoimmune Nodopathies Open
Our data suggest that different B-cell responses may occur in autoimmune nodopathies and may serve as markers of courses of disease and response to rituximab.
View article: High serum prevalence of autoreactive IgG antibodies against peripheral nerve structures in patients with neurological post-COVID-19 vaccination syndrome
High serum prevalence of autoreactive IgG antibodies against peripheral nerve structures in patients with neurological post-COVID-19 vaccination syndrome Open
Background Patients suffering from neurological symptoms after COVID-19 vaccination (post-COVID-19 vaccination syndrome (PCVS)) have imposed an increasing challenge on medical practice, as diagnostic precision and therapeutic options are l…
View article: Molecular dissection of an immunodominant epitope in Kv1.2-exclusive autoimmunity
Molecular dissection of an immunodominant epitope in Kv1.2-exclusive autoimmunity Open
Introduction Subgroups of autoantibodies directed against voltage-gated potassium channel (K v ) complex components have been associated with immunotherapy-responsive clinical syndromes. The high prevalence and the role of autoantibodies d…
View article: KCNA2 IgG autoimmunity in neuropsychiatric diseases
KCNA2 IgG autoimmunity in neuropsychiatric diseases Open
Our data suggest that KCNA2 autoimmunity is clinically heterogeneous. Future studies should determine whether KCNA2 autoantibodies are directly pathogenic or develop secondarily. Early immunotherapy should be considered, in particular if a…
View article: KCNA2 IgG Autoimmunity In Neuropsychiatric Diseases
KCNA2 IgG Autoimmunity In Neuropsychiatric Diseases Open
One patient of the cohort (#25) received a temporal lobe biopsy to rule out a malignant disease. Histological and immunohistochemical images of diagnostic sections are shown. From these images regions of interest are shown in Figure 2.
View article: KCNA2 IgG Autoimmunity In Neuropsychiatric Diseases
KCNA2 IgG Autoimmunity In Neuropsychiatric Diseases Open
One patient of the cohort (#25) received a temporal lobe biopsy to rule out a malignant disease. Histological and immunohistochemical images of diagnostic sections are shown. From these images regions of interest are shown in Figure 2.
View article: Anti-NMDA Receptor Encephalitis in a Patient with Tuberous Sclerosis-Related Brain Tumor: A Case Report
Anti-NMDA Receptor Encephalitis in a Patient with Tuberous Sclerosis-Related Brain Tumor: A Case Report Open
Anti-NMDA receptor (NMDAR) encephalitis (NMDARE) is an important treatable cause of autoimmune psychosis in all age-groups, which is sometimes associated with tumors, especially ovarian teratomas. Tuberous sclerosis complex (TSC) is an aut…
View article: Zeb2 is essential for Schwann cell differentiation, myelination and nerve repair
Zeb2 is essential for Schwann cell differentiation, myelination and nerve repair Open
View article: Curcumin therapy in a <i>Plp1</i> transgenic mouse model of Pelizaeus‐Merzbacher disease
Curcumin therapy in a <i>Plp1</i> transgenic mouse model of Pelizaeus‐Merzbacher disease Open
Curcumin may potentially serve as an antioxidant therapy of PMD caused by PLP1 gene duplication.