Friederike Stephani
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View article: Deletion of the Ca2+ Channel Subunit α2δ3 Differentially Affects Cav2.1 and Cav2.2 Currents in Cultured Spiral Ganglion Neurons Before and After the Onset of Hearing
Deletion of the Ca2+ Channel Subunit α2δ3 Differentially Affects Cav2.1 and Cav2.2 Currents in Cultured Spiral Ganglion Neurons Before and After the Onset of Hearing Open
Voltage-gated Ca2+ channels are composed of a pore-forming α1 subunit and auxiliary β and α2δ subunits, which modulate Ca2+ current properties and channel trafficking. So far, the partial redundancy and specificity of α1 for α2δ subunits i…
View article: α2δ3 is the preferred auxiliary α2δ subunit of Cav2.1 channels in spiral ganglion neurons and is required for development of auditory nerve fiber synapses
α2δ3 is the preferred auxiliary α2δ subunit of Cav2.1 channels in spiral ganglion neurons and is required for development of auditory nerve fiber synapses Open
Voltage-gated calcium channels (VGCCs) are composed of a pore-forming α1 subunit and the
\nauxiliary β and α2δ subunits. The largely extracellular α2δ proteins α2δ1-4 modulate the Ca2+
\ncurrent properties but the reasons for their partial…