Fan Yang
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View article: Cross-media dynamics and prioritized risks of PFAS in textile-impacted environments: using geospatial machine learning
Cross-media dynamics and prioritized risks of PFAS in textile-impacted environments: using geospatial machine learning Open
Per- and polyfluoroalkyl substances (PFAS) from textile receiving environment pose multifaceted environmental risks, yet their cross-media dynamics remain poorly understood due to limitations in traditional correlation-based models. This s…
View article: Correlation between age-friendly communities and post-stroke depression
Correlation between age-friendly communities and post-stroke depression Open
Enhancements in housing, outdoor areas, and civic engagement could reduce the PSD burden and promote the integration of AFC principles into stroke recovery strategies.
View article: Electrocardiographic and clinical predictors for in-hospital mortality in patients with acute myocardial infarction caused by left main coronary artery occlusion
Electrocardiographic and clinical predictors for in-hospital mortality in patients with acute myocardial infarction caused by left main coronary artery occlusion Open
The data on prediction for early mortality in patients with acute myocardial infarction (AMI) caused by total left main (LM) occlusion are limited. We aim to evaluate predictors for early mortality in these extremely high-risk patients. In…
View article: Oral contrast-enhanced ultrasonographic features and radiomics analysis to predict NIH risk stratification for gastrointestinal stromal tumors
Oral contrast-enhanced ultrasonographic features and radiomics analysis to predict NIH risk stratification for gastrointestinal stromal tumors Open
Objective To evaluate the value of oral contrast-enhanced ultrasonography and radiomics analysis in predicting the National Institutes of Health (NIH) staging of gastrointestinal stromal tumors (GISTs). Methods A retrospective cohort study…
View article: A deep learning model combining circulating tumor cells and radiological features in the multi-classification of mediastinal lesions in comparison with thoracic surgeons: a large-scale retrospective study
A deep learning model combining circulating tumor cells and radiological features in the multi-classification of mediastinal lesions in comparison with thoracic surgeons: a large-scale retrospective study Open
This study showed the feasibility and effectiveness of CNN model combing CT images and CTCs levels in predicting the diagnosis of mediastinal lesions. It could serve as a useful method to assist thoracic surgeons in improving diagnostic ac…
View article: Benzyl isothiocyanate provokes senolysis by targeting AKT in senescent IPF fibroblasts and reverses persistent pulmonary fibrosis in aged mice
Benzyl isothiocyanate provokes senolysis by targeting AKT in senescent IPF fibroblasts and reverses persistent pulmonary fibrosis in aged mice Open
Introduction Senescent cells (SCs) accumulate with age and play a causative role in age-related diseases, such as idiopathic pulmonary fibrosis (IPF). Clearance of SCs attenuates lung fibrogenesis and favors fibrosis resolution, suggesting…
View article: Roxadustat effectiveness versus ESAs in peritoneal dialysis patients during the COVID-19 pandemic: A retrospective study
Roxadustat effectiveness versus ESAs in peritoneal dialysis patients during the COVID-19 pandemic: A retrospective study Open
Background The COVID-19 pandemic has made treating renal anemia in chronic kidney disease (CKD) patients undergoing peritoneal dialysis (PD) difficult. The current study aims to compare roxadustat with erythropoiesis-stimulating agents (ES…
View article: Ultrasonic radiomics in predicting pathologic type for thyroid cancer: a preliminary study using radiomics features for predicting medullary thyroid carcinoma
Ultrasonic radiomics in predicting pathologic type for thyroid cancer: a preliminary study using radiomics features for predicting medullary thyroid carcinoma Open
Introduction Medullary thyroid carcinoma (MTC) is aggressive and difficult to distinguish from papillary thyroid carcinoma (PTC) using traditional ultrasound. Objective to establish a standard-based ultrasound imaging model for preoperativ…
View article: Anisotropic adams’ type inequality with exact growth in R4${\mathbb{R}}^{4}$
Anisotropic adams’ type inequality with exact growth in R4${\mathbb{R}}^{4}$ Open
In this paper, we mainly extend the classical Adams’ inequality to its anisotropic type. By using the rearrangement argument, we establish best constants for anisotropic Adams’ type inequality with exact growth in R 4 ${\mathbb{R}}…
View article: Efficacy and safety of low-dose TBI combined MAC regimen for HSCT in high-risk AML patients with active disease
Efficacy and safety of low-dose TBI combined MAC regimen for HSCT in high-risk AML patients with active disease Open
The FACT regimen is an effective myeloablative conditioning (MAC) strategy for high-risk AML patients, potentially reducing relapse risk without increasing NRM, warranting further research.
View article: Association of hospital teaching characteristics with readmission and complication outcomes among patients receiving radiotherapy and brachytherapy for breast cancer: A Nationwide Readmissions Database Analysis
Association of hospital teaching characteristics with readmission and complication outcomes among patients receiving radiotherapy and brachytherapy for breast cancer: A Nationwide Readmissions Database Analysis Open
Background Radiotherapy and brachytherapy are common treatments for breast cancer, but few studies have examined the impact of hospital characteristics on patient outcomes. This study evaluated the influence of hospital teaching status on …
View article: Mesenchymal stem cells and their exosomes mitigate osteoarthritis by restoring the balance between proinflammatory Teffs and Tregs
Mesenchymal stem cells and their exosomes mitigate osteoarthritis by restoring the balance between proinflammatory Teffs and Tregs Open
Osteoarthritis (OA) is a degenerative joint disease caused by chronic inflammation that damages articular cartilage. In addition to the wear and tear of joints, aberrant remodelling driven by a significant presence of inflammatory mediator…
View article: Comparable cognitive impairment was detected in MACS and CS and alleviated after remission of hypercortisolism in MACS
Comparable cognitive impairment was detected in MACS and CS and alleviated after remission of hypercortisolism in MACS Open
Context Few studies have directly compared the cognitive characteristics of patients with mild autonomous cortisol secretion (MACS) and Cushing’s syndrome (CS). The effect of surgical or conservative treatment on cognitive function in pati…
View article: A retrospective study on the efficacy of Roxadustat in peritoneal dialysis patients with erythropoietin hyporesponsiveness
A retrospective study on the efficacy of Roxadustat in peritoneal dialysis patients with erythropoietin hyporesponsiveness Open
Background/Aims: Roxadustat, an oral medication for treating renal anemia, is a hypoxia-inducible factor prolyl hydroxylase inhibitor used for regulating iron metabolism and promoting erythropoiesis. To investigate the efficacy and safety …
View article: Effect of CO2 fractional laser combined with recombinant human epidermal growth factor gel on skin barrier
Effect of CO2 fractional laser combined with recombinant human epidermal growth factor gel on skin barrier Open
To evaluate the impact of CO 2 fractional laser combined with recombinant human epidermal growth factor (rhEGF) gel on skin barrier in acne scar patients. In a retrospective analysis, we examined 105 acne scar patients admitted between Jul…
View article: Characteristics of fine particle matters at the top of Shanghai Tower
Characteristics of fine particle matters at the top of Shanghai Tower Open
To investigate the physical and chemical processes of fine particle matters at mid-upper planetary boundary layer (PBL), we conducted one-year continuous measurements of fine particle matters (PM), chemical composition of non-refractory su…
View article: The acute toxic effect of Chinese medicine Fuzi is exacerbated in kidney yang deficiency mice due to metabolic difference
The acute toxic effect of Chinese medicine Fuzi is exacerbated in kidney yang deficiency mice due to metabolic difference Open
In conclusion, our study showed that changes of the metabolic enzyme activity in individuals with different syndromes led to different toxic effects of Chinese medicines, emphasizing the crucial importance of considering individual physica…
View article: Phase separation of SHP2E76K promotes malignant transformation of mesenchymal stem cells by activating mitochondrial complexes
Phase separation of SHP2E76K promotes malignant transformation of mesenchymal stem cells by activating mitochondrial complexes Open
Mesenchymal stem cells (MSCs), suffering from diverse gene hits, undergo malignant transformation and aberrant osteochondral differentiation. Src homology region 2-containing protein tyrosine phosphatase 2 (SHP2), a nonreceptor protein tyr…
View article: Allo-HSCT with TBI-based preconditioning for hepatosplenic T-cell lymphoma: two case reports and systematic review of literature
Allo-HSCT with TBI-based preconditioning for hepatosplenic T-cell lymphoma: two case reports and systematic review of literature Open
Hepatosplenic T cell lymphoma (HSTCL) is a particularly difficult-to-treat form of lymphoma, with many patients exhibiting primary resistance to chemotherapy. At present, no effective strategy for treating relapsed and refractory HSTCL has…
View article: [Corrigendum] Long non‑coding RNA HR1 participates in the expression of SREBP‑1c through phosphorylation of the PDK1/AKT/FoxO1 pathway
[Corrigendum] Long non‑coding RNA HR1 participates in the expression of SREBP‑1c through phosphorylation of the PDK1/AKT/FoxO1 pathway Open
Subsequently to the publication of the above article, an interested reader drew to the authors' attention that the data panel for the "Huh7+BSA" experiment shown in Fig. 1D on p. 2852, showing the relative size of lipid droplets as determi…
View article: Altered static and dynamic intrinsic brain activity in unilateral sudden sensorineural hearing loss
Altered static and dynamic intrinsic brain activity in unilateral sudden sensorineural hearing loss Open
Introduction Sudden sensorineural hearing loss (SSHL) is a critical otologic emergency characterized by a rapid decline of at least 30 dB across three consecutive frequencies in the pure-tone audiogram within a 72-hour period. This audiolo…
View article: Dynamic covariance estimation via predictive Wishart process with an application on brain connectivity estimation
Dynamic covariance estimation via predictive Wishart process with an application on brain connectivity estimation Open
Modeling the complex dependence in multivariate time series data is a fundamental problem in statistics and machine learning. Traditionally, the task has been approached with methods such as multivariate autoregressive models and multivari…