Furqan Kabir
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View article: Unsafe to eat? A systematic review of heavy metal contamination in urban street foods: Sources, risks, and regional disparities
Unsafe to eat? A systematic review of heavy metal contamination in urban street foods: Sources, risks, and regional disparities Open
View article: Optimizing <i>Shigella</i> isolation: A multi-site evaluation of laboratory culture methods for <i>Shigella</i> detection, speciation, and serotyping with different transport media and sample types in the Enterics for Global Health study
Optimizing <i>Shigella</i> isolation: A multi-site evaluation of laboratory culture methods for <i>Shigella</i> detection, speciation, and serotyping with different transport media and sample types in the Enterics for Global Health study Open
Shigella is a leading cause of diarrhea and dysentery in children under 5 in low- resource settings and several vaccines are in development. Due to its fastidious nature, Shigella can be difficult to culture and eventual vaccine trials wil…
View article: Study of SARS-CoV-2 genomes from Pakistan in the post-pandemic period 2023-2024 shows unique phylogenetic diversity as compared with other global data
Study of SARS-CoV-2 genomes from Pakistan in the post-pandemic period 2023-2024 shows unique phylogenetic diversity as compared with other global data Open
Introduction SARS-CoV-2 infections caused a global pandemic between 2019 and 2023. Omicron variants continued to emerge but morbidity and mortality were reduced likely due to vaccinations and increasing host immunity. COVID-19 case numbers…
View article: Distribution of capsule and O types in Klebsiella pneumoniae causing neonatal sepsis in Africa and South Asia: meta-analysis of genome-predicted serotype prevalence to inform potential vaccine coverage
Distribution of capsule and O types in Klebsiella pneumoniae causing neonatal sepsis in Africa and South Asia: meta-analysis of genome-predicted serotype prevalence to inform potential vaccine coverage Open
Background: Klebsiella pneumoniae causes ~20% of sepsis in neonates, with ~40% crude mortality. A vaccine administered to pregnant women, protecting against 70% of K. pneumoniae infections, could avert ~400,000 cases and ~80,000 deaths ann…
View article: Effectiveness of Monovalent Rotavirus Vaccine Among Young Children in Pakistan: a Test-Negative Case-Control Evaluation
Effectiveness of Monovalent Rotavirus Vaccine Among Young Children in Pakistan: a Test-Negative Case-Control Evaluation Open
Background Pakistan ranks among top 4 countries with greatest number of rotavirus deaths among young children. To reduce the burden of severe rotavirus disease, Pakistan began rolling out the monovalent oral rotavirus vaccine, Rotarix (RV1…
View article: Smoking Prevalence Among Khulna University Students
Smoking Prevalence Among Khulna University Students Open
Background: Smoking is still a significant global public health concern, especially for young people who are more likely to start and maintain smoking habits that could result in long-term health problems. The current study aims to measure…
View article: Effect of one prophylactic dose of azithromycin on Bifidobacterium infantis colonization in infants from the Mumta trial
Effect of one prophylactic dose of azithromycin on Bifidobacterium infantis colonization in infants from the Mumta trial Open
AZ administration was associated with a 1.99-fold (95% confidence intervals [CI] 1.33-2.97) increase in colonization by B. infantis. B. infantis colonization was highest when inflammatory biomarker levels were within normal range. Mode of …
View article: Identification of differentially expressed non-coding RNAs in the plasma of women with preterm birth
Identification of differentially expressed non-coding RNAs in the plasma of women with preterm birth Open
This study aimed to identify differentially expressed non-coding RNAs (ncRNAs) associated with preterm birth (PTB) and determine biological pathways being influenced in the context of PTB. We processed cell-free RNA sequencing data and ide…
View article: Diagnostic Challenges for Detection of Pediatric Acute Megakaryoblastic Leukemia (Amkl): A Case Report
Diagnostic Challenges for Detection of Pediatric Acute Megakaryoblastic Leukemia (Amkl): A Case Report Open
View article: An Analytical Study of Influencing Factors in Private University Enrollment in Bangladesh
An Analytical Study of Influencing Factors in Private University Enrollment in Bangladesh Open
View article: Enteric pathogens relationship with small bowel histologic features of environmental enteric dysfunction in a multicountry cohort study
Enteric pathogens relationship with small bowel histologic features of environmental enteric dysfunction in a multicountry cohort study Open
The detection of some enteropathogens in asymptomatic infections is associated with subsequent EED histopathology. These novel findings offer a basis for future EED etiology and pathogenesis studies.
View article: Pneumococcal carriage and changes in serotype distribution post- PCV13 introduction in children in Matiari, Pakistan
Pneumococcal carriage and changes in serotype distribution post- PCV13 introduction in children in Matiari, Pakistan Open
Replacing PCV10 with PCV13 rapidly decreased prevalence of PCV13 carriage among vaccinated children in Matiari, Pakistan. Vaccine-driven selection pressure may have been responsible for the increase of non-PCV13 serotypes.
View article: A shared group of bacterial taxa in the duodenal microbiota of undernourished Pakistani children with environmental enteric dysfunction
A shared group of bacterial taxa in the duodenal microbiota of undernourished Pakistani children with environmental enteric dysfunction Open
Environmental enteric dysfunction (EED) is a subclinical syndrome of altered small intestinal function postulated to be an important contributor to childhood undernutrition. The role of small intestinal bacterial communities in the pathoph…
View article: Clinical Severity of Enteric Viruses Detected Using a Quantitative Molecular Assay Compared With Conventional Assays in the Global Enteric Multicenter Study
Clinical Severity of Enteric Viruses Detected Using a Quantitative Molecular Assay Compared With Conventional Assays in the Global Enteric Multicenter Study Open
Background Quantitative molecular assays are increasingly used for detection of enteric viruses. Methods We compared the clinical severity using the modified Vesikari score (mVS) of enteric viruses detected by conventional assays (enzyme i…
View article: Strain features of pneumococcal isolates in the pre- and post-PCV10 era in Pakistan
Strain features of pneumococcal isolates in the pre- and post-PCV10 era in Pakistan Open
Pakistan is amongst the four countries with the highest number of pneumococcal deaths. While the PCV10 vaccine was introduced in Pakistan in October 2012, data regarding the impact of the vaccine on the population dynamics of Streptococcus…
View article: Predicting Chronic Obstructive Pulmonary Disease Using ML and DL Approaches and Feature Fusion of X-Ray Image and Patient History
Predicting Chronic Obstructive Pulmonary Disease Using ML and DL Approaches and Feature Fusion of X-Ray Image and Patient History Open
View article: Building up a genomic surveillance platform for SARS-CoV-2 in the middle of a pandemic: a true North–South collaboration
Building up a genomic surveillance platform for SARS-CoV-2 in the middle of a pandemic: a true North–South collaboration Open
Next-generation sequencing technology has revolutionised pathogen surveillance over the last two decades. However, the benefits are not equitably distributed, with developing countries lagging far behind in acquiring the required technolog…
View article: Association of maternal prenatal copper concentration with gestational duration and preterm birth: a multicountry meta-analysis
Association of maternal prenatal copper concentration with gestational duration and preterm birth: a multicountry meta-analysis Open
Our study supports robust negative association between maternal Cu and gestational duration and positive association with risk for PTB. Cu concentration was strongly correlated with APRs and infection status suggesting its potential role i…
View article: Environmental surveillance for COVID-19 using SARS-CoV-2 RNA concentration in wastewater – a study in District East, Karachi, Pakistan
Environmental surveillance for COVID-19 using SARS-CoV-2 RNA concentration in wastewater – a study in District East, Karachi, Pakistan Open
View article: Sequential viral introductions and spread of BA.1 across Pakistan provinces during the Omicron wave
Sequential viral introductions and spread of BA.1 across Pakistan provinces during the Omicron wave Open
View article: Multiomic signals associated with maternal epidemiological factors contributing to preterm birth in low- and middle-income countries
Multiomic signals associated with maternal epidemiological factors contributing to preterm birth in low- and middle-income countries Open
Preterm birth (PTB) is the leading cause of death in children under five, yet comprehensive studies are hindered by its multiple complex etiologies. Epidemiological associations between PTB and maternal characteristics have been previously…
View article: Co-carriage of Staphylococcus aureus and Streptococcus pneumoniae among children younger than 2 years of age in a rural population in Pakistan
Co-carriage of Staphylococcus aureus and Streptococcus pneumoniae among children younger than 2 years of age in a rural population in Pakistan Open
View article: Sequential viral introductions and spread of BA.1 drove the Omicron wave across Pakistani provinces
Sequential viral introductions and spread of BA.1 drove the Omicron wave across Pakistani provinces Open
Background COVID-19 waves caused by specific SARS-CoV-2 variants have occurred globally at different times. We focused on Omicron variants to understand the genomic diversity and phylogenetic relatedness of SARS-CoV-2 strains in various re…
View article: Impact of enteropathogens on faltering growth in a resource-limited setting
Impact of enteropathogens on faltering growth in a resource-limited setting Open
Introduction Environmental enteropathy is an important contributor to childhood malnutrition in the developing world. Chronic exposure to fecal pathogens leads to alteration in intestinal structure and function, resulting in impaired gut i…
View article: Additional file 1 of Sequential viral introductions and spread of BA.1 across Pakistan provinces during the Omicron wave
Additional file 1 of Sequential viral introductions and spread of BA.1 across Pakistan provinces during the Omicron wave Open
Additional file 1.
View article: Author Correction: Prediction of gestational age using urinary metabolites in term and preterm pregnancies
Author Correction: Prediction of gestational age using urinary metabolites in term and preterm pregnancies Open
View article: Association of maternal prenatal copper concentration with gestational duration and preterm birth: a multi-country meta-analysis
Association of maternal prenatal copper concentration with gestational duration and preterm birth: a multi-country meta-analysis Open
Background Copper (Cu), an essential trace mineral regulating multiple actions of inflammation and oxidative stress, has been implicated in risk for preterm birth (PTB). We aimed to determine the association of maternal plasma/serum Cu con…
View article: Pneumococcal Carriage in Infants Post-PCV10 Introduction in Pakistan: Results from Serial Cross-Sectional Surveys
Pneumococcal Carriage in Infants Post-PCV10 Introduction in Pakistan: Results from Serial Cross-Sectional Surveys Open
The 10-valent pneumococcal vaccine was introduced in Pakistan’s Expanded Program on Immunization (EPI) in 2013 as a 3 + 0 schedule without catchup. We conducted three annual cross-sectional surveys from 2014–2016 to measure vaccine-type (V…
View article: Pneumococcal Carriage in Infants Post-PCV10 Introduction in Pakistan: Results from Serial Cross-Sectional Surveys
Pneumococcal Carriage in Infants Post-PCV10 Introduction in Pakistan: Results from Serial Cross-Sectional Surveys Open
The 10-valent pneumococcal vaccine was introduced in Pakistan’s Expanded Program on Immunization (EPI) in 2013 as a 3+0 schedule without catchup. We conducted three annual cross-sectional surveys from 2014-2016 to measure vaccine-typ…
View article: Prediction of gestational age using urinary metabolites in term and preterm pregnancies
Prediction of gestational age using urinary metabolites in term and preterm pregnancies Open
Assessment of gestational age (GA) is key to provide optimal care during pregnancy. However, its accurate determination remains challenging in low- and middle-income countries, where access to obstetric ultrasound is limited. Hence, there …