Fang Tian
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View article: Proteomics reveals the regulation of ALG1 expression by lentivirus‑mediated THBS1 overexpression and its mechanism in meibomian gland carcinoma
Proteomics reveals the regulation of ALG1 expression by lentivirus‑mediated THBS1 overexpression and its mechanism in meibomian gland carcinoma Open
Meibomian gland carcinoma (MGC) is a highly aggressive eyelid malignancy with a poor prognosis. MicroRNA-3907 (miR-3907) is upregulated in MGC, where it promotes tumor progression by suppressing thrombospondin 1 (THBS1). The present study …
View article: The duplexity of insulin: The integrated bioinformatics analysis and machine learning identified key genes for type 2 diabetes
The duplexity of insulin: The integrated bioinformatics analysis and machine learning identified key genes for type 2 diabetes Open
View article: Assessing the interchangeability of keratometry measurements from four biometric devices in intraocular lens power calculations: insights into the predictive accuracy of five modern IOL formulas
Assessing the interchangeability of keratometry measurements from four biometric devices in intraocular lens power calculations: insights into the predictive accuracy of five modern IOL formulas Open
View article: Matrix3D: Large Photogrammetry Model All-in-One
Matrix3D: Large Photogrammetry Model All-in-One Open
We present Matrix3D, a unified model that performs several photogrammetry subtasks, including pose estimation, depth prediction, and novel view synthesis using just the same model. Matrix3D utilizes a multi-modal diffusion transformer (DiT…
View article: Functional, Biotinylproteomic and Bioinformatic Analysis of Both Cytoskeletal and Plastoskeletal Proteins in Plant Mechanoresponse
Functional, Biotinylproteomic and Bioinformatic Analysis of Both Cytoskeletal and Plastoskeletal Proteins in Plant Mechanoresponse Open
To investigate the early signaling components of skeletal proteins in mediating Arabidopsis thigmomorphogenesis, both microscopic and proximity labeling (PL)-based quantitative biotinylproteomics were applied to investigate the subcellular…
View article: Identification of ETV5 as a prognostic marker related to epigenetic modification in pan-cancer and facilitates tumor progression in hepatocellular carcinoma
Identification of ETV5 as a prognostic marker related to epigenetic modification in pan-cancer and facilitates tumor progression in hepatocellular carcinoma Open
ETS variant transcription factor 5 (ETV5), a master transcription factor during development, exerts vital function on the occurrence and progression of various cancers. In order to systematically analyze and explore ETV5 potential specific…
View article: Dynamic ultrasonography helps diagnose calcium pyrophosphate deposition disease
Dynamic ultrasonography helps diagnose calcium pyrophosphate deposition disease Open
View article: Three months use of Hybrid Closed Loop Systems improves glycated hemoglobin levels in adolescents and children with type 1 diabetes: A meta-analysis
Three months use of Hybrid Closed Loop Systems improves glycated hemoglobin levels in adolescents and children with type 1 diabetes: A meta-analysis Open
Background Longer outpatient studies have demonstrated that hybrid closed loop (HCL) use has led to a concomitant reduction in glycated hemoglobin(HbA1c) by 0.3%–0.7%. However, reports have also indicated that HbA1c levels are not declined…
View article: MCP-1 Regulates Fractalkine Secretion through p38MAPK Signaling Pathway in Rats with Advanced Bone Cancer Pain
MCP-1 Regulates Fractalkine Secretion through p38MAPK Signaling Pathway in Rats with Advanced Bone Cancer Pain Open
To explore the effect and mechanism of monocyte chemoattractant-1 regulating fractalkine secretion of neurons through p38mitogen-activated protein kinase signaling pathway in rats with advanced bone cancer pain. 30 adult female Sprague-Daw…
View article: Comparison of two swept-source optical coherence tomography devices, a Scheimpflug camera system and a ray-tracing aberrometer in the measurement of corneal power in patients with cataract
Comparison of two swept-source optical coherence tomography devices, a Scheimpflug camera system and a ray-tracing aberrometer in the measurement of corneal power in patients with cataract Open
Purpose To assess the differences and similarities in the corneal curvature obtained by two swept-source optical coherence tomography (SS-OCT) devices, Scheimpflug imaging system and one ray tracing aberrometer in patients with cataracts. …
View article: 2367P A randomized phase II study of atezolizumab (atezo) plus recombinant human IL-7 (CYT107) vs. atezo alone in patients with locally advanced or metastatic urothelial carcinoma (mUC)
2367P A randomized phase II study of atezolizumab (atezo) plus recombinant human IL-7 (CYT107) vs. atezo alone in patients with locally advanced or metastatic urothelial carcinoma (mUC) Open
View article: Plasmin-Induced Lens Epithelial Cells Detachment for the Reduction of Posterior Capsular Opacification
Plasmin-Induced Lens Epithelial Cells Detachment for the Reduction of Posterior Capsular Opacification Open
Plasmin injection for lens epithelial cell detachment could significantly decrease the number of residual lens epithelial cells. This approach could be a promising treatment incorporating the current treatment approach to further improve t…
View article: Data from Expression of the p53 Target CDIP Correlates with Sensitivity to TNFα-Induced Apoptosis in Cancer Cells
Data from Expression of the p53 Target CDIP Correlates with Sensitivity to TNFα-Induced Apoptosis in Cancer Cells Open
TNFα is a pleiotropic cytokine that signals for both survival and apoptotic cell fates. It is still unclear that the dual role of TNFα can be regulated in cancer cells. We previously described an apoptotic pathway involving p53→CDIP→TNFα t…
View article: NeILF++: Inter-Reflectable Light Fields for Geometry and Material Estimation
NeILF++: Inter-Reflectable Light Fields for Geometry and Material Estimation Open
We present a novel differentiable rendering framework for joint geometry, material, and lighting estimation from multi-view images. In contrast to previous methods which assume a simplified environment map or co-located flashlights, in thi…
View article: Data from Expression of the p53 Target CDIP Correlates with Sensitivity to TNFα-Induced Apoptosis in Cancer Cells
Data from Expression of the p53 Target CDIP Correlates with Sensitivity to TNFα-Induced Apoptosis in Cancer Cells Open
TNFα is a pleiotropic cytokine that signals for both survival and apoptotic cell fates. It is still unclear that the dual role of TNFα can be regulated in cancer cells. We previously described an apoptotic pathway involving p53→CDIP→TNFα t…
View article: Benzonatate Exposure Trends and Adverse Events
Benzonatate Exposure Trends and Adverse Events Open
BACKGROUND AND OBJECTIVES Adverse events (AE), including death, occur in children with benzonatate use. This study aims to understand recent trends in benzonatate exposure and clinical consequences in pediatric patients. METHODS This retro…
View article: Dissecting lncRNA-mRNA competitive regulatory network in human islet tissue exosomes of a type 1 diabetes model reveals exosome miRNA markers
Dissecting lncRNA-mRNA competitive regulatory network in human islet tissue exosomes of a type 1 diabetes model reveals exosome miRNA markers Open
Background Emerging evidence shows that exosomes play a crucial role in the occurrence and development of diabetes and its complications. The molecules in exosomes can be regarded as important markers for the diagnosis of diseases. However…
View article: 510 A PD-L1 reporter cell line based on the immune checkpoint protein profiling of ATCC cell lines facilitates cancer immunotherapy drug screening
510 A PD-L1 reporter cell line based on the immune checkpoint protein profiling of ATCC cell lines facilitates cancer immunotherapy drug screening Open
Background The success of immune checkpoint inhibitors in the treatment of various types of cancers and their continued growth in the market have driven burgeoning interests in developing more drugs in this category. However, the intrinsic…
View article: 220 Luciferase reporter cancer cell lines facilitate CAR-T development
220 Luciferase reporter cancer cell lines facilitate CAR-T development Open
Background Chimeric antigen receptor (CAR)-T cells have displayed remarkable efficacy in treating malignant cancers, particularly liquid tumors. CAR-T cells have proven to be a new type of "living" therapeutic by harnessing the patient's i…
View article: Evaluation of the effect of gentamicin in surgical perfusion solution on cataract postoperative endophthalmitis
Evaluation of the effect of gentamicin in surgical perfusion solution on cataract postoperative endophthalmitis Open
Objective To evaluate the effect of gentamicin in surgical perfusion solution on endophthalmitis incidence after cataract surgery. Methods A retrospective analysis of endophthalmitis incidence was conducted in two groups of patients who un…
View article: Cuproptosis scoring model predicts overall survival and assists in immunotherapeutic decision making in pancreatic carcinoma
Cuproptosis scoring model predicts overall survival and assists in immunotherapeutic decision making in pancreatic carcinoma Open
Background: Cuproptosis is a newly identified form of non-apoptotic cell death that is associated with the progression and treatment responses in pancreatic adenocarcinoma (PAAD). However, its impact on oncology and tumor microenvironment …
View article: Senescence marker protein30 protects lens epithelial cells against oxidative damage by restoring mitochondrial function
Senescence marker protein30 protects lens epithelial cells against oxidative damage by restoring mitochondrial function Open
Etiology and pathogenesis of age-related cataract is not entirely clear till now. Senescence marker protein 30 (SMP30) is a newly discovered anti-aging factor, which plays an important role in preventing apoptosis and reducing oxidative st…
View article: NeILF: Neural Incident Light Field for Physically-based Material Estimation
NeILF: Neural Incident Light Field for Physically-based Material Estimation Open
We present a differentiable rendering framework for material and lighting estimation from multi-view images and a reconstructed geometry. In the framework, we represent scene lightings as the Neural Incident Light Field (NeILF) and materia…
View article: Correlation Between Matrix Metalloproteinases With Coronary Artery Lesion Caused by Kawasaki Disease
Correlation Between Matrix Metalloproteinases With Coronary Artery Lesion Caused by Kawasaki Disease Open
This study was designed to clarify the role of matrix metalloproteinases (MMPs) in coronary artery lesions (CAL). Serum samples were acquired from healthy, febrile, and Kawasaki disease (KD) children with or without CAL. Standard blood par…
View article: Changes in Retinal Vasculature and Thickness After Femtosecond Laser-assisted Cataract Surgery and Conventional Cataract Surgery Using Optical Coherence Tomography Angiography
Changes in Retinal Vasculature and Thickness After Femtosecond Laser-assisted Cataract Surgery and Conventional Cataract Surgery Using Optical Coherence Tomography Angiography Open
Purpose To assess the changes in retinal vasculature and thickness after femtosecond laser-assisted cataract surgery (FLACS) using optical coherence tomography angiography (OCTA). Methods Fifty-six eyes of 56 patients with age-related cata…
View article: Retinal Vascular changes in Femtosecond Laser-Assisted Cataract Surgery by Optical Coherence Tomography Angiography
Retinal Vascular changes in Femtosecond Laser-Assisted Cataract Surgery by Optical Coherence Tomography Angiography Open
Purpose To assess the changes in retinal vasculature and thickness after femtosecond laser-assisted cataract surgery (FLACS) using optical coherence tomography angiography (OCTA). Methods Fifty-six eyes of 56 patients with age-related cata…
View article: Effect of tea tree oil eye patch combined with eyelid margin deep cleaning device in treating demodex blepharitis
Effect of tea tree oil eye patch combined with eyelid margin deep cleaning device in treating demodex blepharitis Open
AIM: To investigate the clinical effect of tea tree oil eye patch combined with eyelid margin deep cleaning device in treating demodex blepharitis. METHODS: This was a prospective, randomized and self-controlled study. Thirty-two patients(…
View article: Changes of miR‑155 expression in serum of uremic patients before and after treatment and risk factors analysis
Changes of miR‑155 expression in serum of uremic patients before and after treatment and risk factors analysis Open
The aim of the present study was to investigate the changes of miR-155 expression in the serum of uremic patients before and after treatment and analyze the risk factors of efficacy. A total of 116 uremic patients admitted to the People's …
View article: Significance of STAT3 in Immune Infiltration and Drug Response in Cancer
Significance of STAT3 in Immune Infiltration and Drug Response in Cancer Open
Signal transducer and activator of transcription 3 (STAT3) is a transcription factor and regulates tumorigenesis. However, the functions of STAT3 in immune and drug response in cancer remain elusive. Hence, we aim to reveal the impact of S…
View article: Circulating MicroRNA-423-3p Improves the Prediction of Coronary Artery Disease in a General Population ― Six-Year Follow-up Results From the China-Cardiovascular Disease Study ―
Circulating MicroRNA-423-3p Improves the Prediction of Coronary Artery Disease in a General Population ― Six-Year Follow-up Results From the China-Cardiovascular Disease Study ― Open
Circulating miR-423-3p can improve the prediction of primary CAD outcomes on the basis of a traditional risk factor model in general population.