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View article: A Multicenter Prospective Cohort Study on the Use of Weight‐Adjusted Dalteparin in Patients Over 90 kg With Acute Cancer‐Associated Venous Thromboembolism—The <scp>WAVe</scp> Study
A Multicenter Prospective Cohort Study on the Use of Weight‐Adjusted Dalteparin in Patients Over 90 kg With Acute Cancer‐Associated Venous Thromboembolism—The <span>WAVe</span> Study Open
Patients with cancer‐associated thrombosis (CAT) are commonly treated with low‐molecular‐weight heparin (LMWH), but whether dose capping is needed in patients over 90 kg is unclear. We conducted the WAVe study, a multicenter prospective co…
View article: Impact of ABO blood groups on residual pulmonary vascular obstruction in patients with unprovoked pulmonary embolism
Impact of ABO blood groups on residual pulmonary vascular obstruction in patients with unprovoked pulmonary embolism Open
Background After completing anticoagulant therapy for acute pulmonary embolism (PE), patients may have persistent thrombotic materials in the lung, causing residual pulmonary vascular obstruction (RPVO). Detectable by imaging, RPVO is asso…
View article: JTH in Clinic: Management of isolated distal deep vein thrombosis
JTH in Clinic: Management of isolated distal deep vein thrombosis Open
Isolated distal deep vein thrombosis (DVT) represents up to 50% of all lower limb DVT in ultrasound-based studies and is a frequent medical condition, which management is not well established. Data arising from registries and nonrandomized…
View article: Racial disparities in the incidence and risk factors of major bleeding during extended anticoagulant therapy for venous thromboembolism
Racial disparities in the incidence and risk factors of major bleeding during extended anticoagulant therapy for venous thromboembolism Open
Black individuals on extended anticoagulation have higher risk of major bleeding compared with White individuals. This effect appears to persist in those classified as low risk for bleeding. Risk assessment models for anticoagulant-associa…
View article: Validation of the ToDay, a simplified diagnostic algorithm for deep vein thrombosis
Validation of the ToDay, a simplified diagnostic algorithm for deep vein thrombosis Open
The ToDay algorithm was found to be a safe and efficient alternative for DVT testing, reducing reliance on ultrasound imaging. It simplifies the diagnostic process, making it more feasible for emergency settings. Prospective validation is …
View article: Corrigendum: Management of Cancer-Associated Thrombosis: Unmet Needs and Future Perspectives
Corrigendum: Management of Cancer-Associated Thrombosis: Unmet Needs and Future Perspectives Open
[This corrects the article DOI: 10.1055/s-0041-1736037.].
View article: Prediction of health-related quality-of-life results after lung stereotactic body radiotherapy using dose-volume parameters from functional mapping on Gallium-68 perfusion PET/CT
Prediction of health-related quality-of-life results after lung stereotactic body radiotherapy using dose-volume parameters from functional mapping on Gallium-68 perfusion PET/CT Open
In our study, increased radiation doses in functional lung volume PET bases dose parameters were significantly associated with a decrease of HRQoL unlike anatomic lung parameters. Functional lung avoidance planning guided by perfusion PET/…
View article: COPD exacerbation purulence status and its association with pulmonary embolism: a systematic review with meta-analysis
COPD exacerbation purulence status and its association with pulmonary embolism: a systematic review with meta-analysis Open
Background Diagnosing pulmonary embolism (PE) in patients with acute exacerbation of COPD (AECOPD) is challenging. Finding predictors of PE could help improve diagnostic management of patients with AECOPD. The aim was to evaluate the assoc…
View article: Role of functional mapping on Gallium-68 perfusion positron emission tomography and computed tomographic imaging (PET/CT) to assess the risk of long-term radiation-induced lung toxicity after stereotactic body radiation therapy
Role of functional mapping on Gallium-68 perfusion positron emission tomography and computed tomographic imaging (PET/CT) to assess the risk of long-term radiation-induced lung toxicity after stereotactic body radiation therapy Open
The predictive value of PET perfusion-based functional parameters outperforms the standard CT-based dose-volume parameters for the risk of grade ≥2 long-term RILT.
View article: Management of bleeding and invasive procedures in patients treated with anti–factor XI(a) anticoagulants: proposals from the French Working Group on Perioperative Haemostasis and French Society of Thrombosis and Haemostasis
Management of bleeding and invasive procedures in patients treated with anti–factor XI(a) anticoagulants: proposals from the French Working Group on Perioperative Haemostasis and French Society of Thrombosis and Haemostasis Open
These proposals will be re-evaluated as more data becomes available. The implementation of a registry for managing anti-FXI(a) anticoagulants in patients undergoing invasive procedures or experiencing bleeding complications is needed.
Sex-specific DNA methylation marks associated with sex-biased risk of recurrence in unprovoked venous thromboembolism Open
We identified DNAm marks as potential risk factors for sex-biased recurrence in unprovoked VTE. Further replication and experimental validation could refine our understanding of the regulation of the identified DNAm sites and help optimize…
View article: Validation of a Simplified Diagnostic Algorithm for Deep Vein Thrombosis
Validation of a Simplified Diagnostic Algorithm for Deep Vein Thrombosis Open
Background: Evidence-based deep vein thrombosis (DVT) diagnostic algorithms used in the emergency department have been extensively validated, yet they are rarely followed by emergency physicians. The most well-known, the Wells score, is co…
View article: Characterizing Diagnostic Investigations for Suspected Pulmonary Embolism in Postpartum Individuals
Characterizing Diagnostic Investigations for Suspected Pulmonary Embolism in Postpartum Individuals Open
Background: Venous thromboembolism (VTE) is a significant concern during pregnancy and the postpartum period, as pulmonary embolism (PE) remains a leading cause of maternal mortality in Western countries and carries serious morbidity inclu…
View article: An assessment of evidence to inform best practice for the communication of acute venous thromboembolism diagnosis: a scoping review
An assessment of evidence to inform best practice for the communication of acute venous thromboembolism diagnosis: a scoping review Open
Background Physician communication with patients is a key aspect of excellent care. Scant evidence exists to inform best practice for physician communication in patients diagnosed with pulmonary embolism and deep vein thrombosis, collectiv…
View article: A toolkit for the collection of thrombosis-related data elements in COVID-19 clinical studies
A toolkit for the collection of thrombosis-related data elements in COVID-19 clinical studies Open
Thrombosis has emerged as an important complication of coronavirus disease 2019 (COVID-19), particularly among individuals with severe illness. However, the precise incidence of thrombotic events remains uncertain due to differences in stu…
View article: Age-Adjusted and Clinical Probability Adapted D-Dimer Cutoffs to Rule Out Pulmonary Embolism: A Narrative Review of Clinical Trials
Age-Adjusted and Clinical Probability Adapted D-Dimer Cutoffs to Rule Out Pulmonary Embolism: A Narrative Review of Clinical Trials Open
Diagnosis of pulmonary embolism remains a challenge for clinicians as its differential diagnosis is wide. The use of sequential diagnostic strategies based on the assessment of clinical probability, D-dimer measurement, and computed tomogr…
View article: Chronic obstructive pulmonary disease exacerbation purulence status and its association with pulmonary embolism: protocol for a systematic review with meta-analysis
Chronic obstructive pulmonary disease exacerbation purulence status and its association with pulmonary embolism: protocol for a systematic review with meta-analysis Open
Introduction Acute exacerbation of chronic obstructive pulmonary disease (AECOPD) increases the risk of pulmonary embolism (PE). AECOPD and PE have similar symptoms which results in a high proportion of patients with AECOPD undergoing imag…
View article: Safety of outpatient management of cancer-associated pulmonary embolism: a retrospective study
Safety of outpatient management of cancer-associated pulmonary embolism: a retrospective study Open
Not available.
Risk of recurrent venous thromboembolism and bleeding in patients with acute isolated subsegmental pulmonary embolism Open
Most patients diagnosed with an acute SSPE received anticoagulation. The incidence of recurrent VTE detected over time was relatively high, especially in patients with cancer.
View article: Comparison of three diagnostic strategies for suspicion of pulmonary embolism: planar ventilation-perfusion scan (V/Q), CT pulmonary angiography (CTPA) and single photon emission CT ventilation-perfusion scan (SPECT V/Q): a protocol of a randomised controlled trial
Comparison of three diagnostic strategies for suspicion of pulmonary embolism: planar ventilation-perfusion scan (V/Q), CT pulmonary angiography (CTPA) and single photon emission CT ventilation-perfusion scan (SPECT V/Q): a protocol of a randomised controlled trial Open
Introduction Pulmonary embolism (PE) is a challenge to diagnose and when missed, exposes patients to potentially fatal recurrent events. Beyond CT pulmonary angiography (CTPA) and planar ventilation/perfusion (V/Q) scan, single photon emis…
Thrombocytopenia with and without thrombosis following COVID-19 vaccination: long-term management Open
Two of 4 patients with VITT developed refractory thrombocytopenia successfully treated with intravenous immunoglobulin, corticosteroids, and plasma exchange therapy. Patients with VITT remained on anticoagulation for at least 9 months due …
Heparin Dose Intensity and Organ Support-Free Days in Patients Hospitalized for COVID-19 Open
Among noncritically ill patients hospitalized for COVID-19 who were randomized to and initially received therapeutic-dose anticoagulation, heparin, compared with usual care, was associated with improved OSFDs, a combination of in-hospital …