Gemma Armengol
YOU?
Author Swipe
View article: Biodose Tools updates for criticality accidents and interlaboratory comparisons
Biodose Tools updates for criticality accidents and interlaboratory comparisons Open
Purpose: Since its initial release, the aim of Biodose Tools was to offer an easy-to-use platform to perform the mathematical calculations needed in biological dosimetry. This update 3.7.1, mainly focuses on new features related to large-s…
View article: How to combine multiple tools for the genetic diagnosis work-up of pediatric B-cell acute lymphoblastic leukemia
How to combine multiple tools for the genetic diagnosis work-up of pediatric B-cell acute lymphoblastic leukemia Open
This study investigated the importance of comprehensive genetic diagnosis in pediatric B-cell acute lymphoblastic leukemia (B-ALL). We analyzed 175 B-ALL employing karyotyping, FISH, MLPA, targeted next-generation sequencing (t-NGS), and O…
View article: Correlation between DNA double strand breaks and cell death in peripheral blood lymphocytes from breast cancer patients
Correlation between DNA double strand breaks and cell death in peripheral blood lymphocytes from breast cancer patients Open
Radiotherapy is an effective treatment to fight cancer. However, it not only affects cancer cells but also healthy tissues, causing side effects. Different factors can influence the appearance of radiotoxicity, like total dose administered…
View article: How to Combine Multiple Tools for the Genetic Diagnosis Work-up of B-Cell Acute Lymphoblastic Leukemia
How to Combine Multiple Tools for the Genetic Diagnosis Work-up of B-Cell Acute Lymphoblastic Leukemia Open
This study investigated the importance of comprehensive genetic diagnosis in pediatric B-cell acute lymphoblastic leukemia (B-ALL). We analyzed 175 B-ALL employing karyotyping, FISH, MLPA, targeted next-generation sequencing (t-NGS), and O…
View article: Differential biological effect of low doses of ionizing radiation depending on the radiosensitivity in a cell line model
Differential biological effect of low doses of ionizing radiation depending on the radiosensitivity in a cell line model Open
Purpose Exposure to low doses (LD) of ionizing radiation (IR), such as the ones employed in computed tomography (CT) examination, can be associated with cancer risk. However, not all individuals respond the same to IR, and cancer developme…
View article: Supplementary Data from Regulation of Replicative and Stress-Induced Senescence by RSK4, which is Down-regulated in Human Tumors
Supplementary Data from Regulation of Replicative and Stress-Induced Senescence by RSK4, which is Down-regulated in Human Tumors Open
Supplementary Data from Regulation of Replicative and Stress-Induced Senescence by RSK4, which is Down-regulated in Human Tumors
View article: Supplementary Data from Regulation of Replicative and Stress-Induced Senescence by RSK4, which is Down-regulated in Human Tumors
Supplementary Data from Regulation of Replicative and Stress-Induced Senescence by RSK4, which is Down-regulated in Human Tumors Open
Supplementary Data from Regulation of Replicative and Stress-Induced Senescence by RSK4, which is Down-regulated in Human Tumors
View article: Data from Regulation of Replicative and Stress-Induced Senescence by RSK4, which is Down-regulated in Human Tumors
Data from Regulation of Replicative and Stress-Induced Senescence by RSK4, which is Down-regulated in Human Tumors Open
Purpose: The control of senescence and its biochemical pathways is a crucial factor for understanding cell transformation. In a large RNA interference screen, the RSK4 gene was found to be related to p53-dependent arrest. The…
View article: Data from Regulation of Replicative and Stress-Induced Senescence by RSK4, which is Down-regulated in Human Tumors
Data from Regulation of Replicative and Stress-Induced Senescence by RSK4, which is Down-regulated in Human Tumors Open
Purpose: The control of senescence and its biochemical pathways is a crucial factor for understanding cell transformation. In a large RNA interference screen, the RSK4 gene was found to be related to p53-dependent arrest. The…
View article: Evaluation of γ-H2AX foci distribution among different peripheral blood mononucleated cell subtypes
Evaluation of γ-H2AX foci distribution among different peripheral blood mononucleated cell subtypes Open
Although different PBMC subsets studied showed different radiation sensitivity, these differences did not explain the overdispersion observed in the γ-H2AX foci distribution after exposure to IR.
View article: Radiation-induced g-H2AX foci in different leukocyte subpopulations
Radiation-induced g-H2AX foci in different leukocyte subpopulations Open
Altres ajuts: Spanish Consejo de Seguridad Nuclear (BOE-A-2019-311)
View article: Differential Radiosensitizing Effect of 50 nm Gold Nanoparticles in Two Cancer Cell Lines
Differential Radiosensitizing Effect of 50 nm Gold Nanoparticles in Two Cancer Cell Lines Open
Radiation therapy is widely used as an anti-neoplastic treatment despite the adverse effects it can cause in non-tumoral tissues. Radiosensitizing agents, which can increase the effect of radiation in tumor cells, such as gold nanoparticle…
View article: Molecular Biomarkers in Cancer
Molecular Biomarkers in Cancer Open
Molecular cancer biomarkers are any measurable molecular indicator of risk of cancer, occurrence of cancer, or patient outcome. They may include germline or somatic genetic variants, epigenetic signatures, transcriptional changes, and prot…
View article: Salivary Dysfunctions and Consequences After Radioiodine Treatment for Thyroid Cancer: Protocol for a Self-Controlled Study (START Study)
Salivary Dysfunctions and Consequences After Radioiodine Treatment for Thyroid Cancer: Protocol for a Self-Controlled Study (START Study) Open
Background Following radioiodine (131I) therapy of differentiated thyroid cancer, the salivary glands may become inflamed, leading to dysfunctions and decreases in patients’ nutritional status and quality of life. The incidence of these dy…
View article: Establishment and validation of surface model for biodosimetry based on γ-H2AX foci detection
Establishment and validation of surface model for biodosimetry based on γ-H2AX foci detection Open
In case of a suspected overexposure to radiation, the surface model here presented allows a correct dose estimation using γ-H2AX foci as biomarker. The advantage of this surface model is that it can be used at any post-irradiation time, in…
View article: Low dose ionizing radiation effects on the immune system
Low dose ionizing radiation effects on the immune system Open
View article: Polymorphisms in MDM2 and TP53 Genes and Risk of Developing Therapy-Related Myeloid Neoplasms
Polymorphisms in MDM2 and TP53 Genes and Risk of Developing Therapy-Related Myeloid Neoplasms Open
View article: Impact of polymorphisms in apoptosis‐related genes on the outcome of childhood acute lymphoblastic leukaemia
Impact of polymorphisms in apoptosis‐related genes on the outcome of childhood acute lymphoblastic leukaemia Open
Despite intensification of therapy, 20% of children with acute lymphoblastic leukaemia (ALL) relapse (Ceppi et al, 2015). The different response to chemotherapy may be partially explained by inherited genetic variants, e.g. single nucleoti…
View article: ¿Pueden las características fisicoquímicas del suelo afectar la presencia de esporas de <i>Bacillus thuringiensis</i>?
¿Pueden las características fisicoquímicas del suelo afectar la presencia de esporas de <i>Bacillus thuringiensis</i>? Open
Departamentos de Colombia se les evaluaron 14 variables fisicoquímicas y la presencia y número de esporas de Bacillus thuringiensis. Posteriormente se realizó un estudio estadístico. No se encontró ninguna regresión simple entre las variab…
View article: Vacunas de ADN: Una nueva y promisoria manera de inducir inmunidad protectora
Vacunas de ADN: Una nueva y promisoria manera de inducir inmunidad protectora Open
La reciente tecnología de las vacunas de ADN representa un paso potencialmente revolucionario en el desarrollo de la vacunación. Su mayor ventaja es su capacidad de generar respuesta inmune celular y humoral, eliminando muchos de los probl…
View article: Differences in DNA Repair Capacity, Cell Death and Transcriptional Response after Irradiation between a Radiosensitive and a Radioresistant Cell Line
Differences in DNA Repair Capacity, Cell Death and Transcriptional Response after Irradiation between a Radiosensitive and a Radioresistant Cell Line Open
View article: Mutations by Next Generation Sequencing in Stool DNA from Colorectal Carcinoma Patients - A Literature Review and our Experience with this Methodology
Mutations by Next Generation Sequencing in Stool DNA from Colorectal Carcinoma Patients - A Literature Review and our Experience with this Methodology Open
It is well-known that colorectal carcinoma is a disease involving multistep carcinogenesis (hyperplasia-adenoma-carcinoma-metastasizing carcinoma). It is also a disease where therapeutically important driver mutations (especially in the EG…
View article: Peritoneal Carcinomatosis and Multi-Organ Metastases are Prognostic Factors in Colorectal Cancer: A Retrospective Analysis
Peritoneal Carcinomatosis and Multi-Organ Metastases are Prognostic Factors in Colorectal Cancer: A Retrospective Analysis Open
Background: Peritoneal carcinomatosis and multi-organ metastases might be prognostic factors in patients with advanced colorectal cancer and inoperable metastases at diagnosis. Methods: A retrospective study was performed to examine the re…
View article: Simultaneous Underexpression of let-7a-5p and let-7f-5p microRNAs in Plasma and Stool Samples from Early Stage Colorectal Carcinoma
Simultaneous Underexpression of let-7a-5p and let-7f-5p microRNAs in Plasma and Stool Samples from Early Stage Colorectal Carcinoma Open
Colorectal cancer (CRC) is the third most common malignancy and the second most common cause of cancer death worldwide. Early detection of CRC can improve patient survival rates; thus, the identification of noninvasive diagnostic markers i…