G. B. Spoelstra
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View article: Vancomycin-based tracers guiding in situ visualization of bacteria on osteosynthesis devices and surgical debridement
Vancomycin-based tracers guiding in situ visualization of bacteria on osteosynthesis devices and surgical debridement Open
Purpose Bacterial infections associated with musculoskeletal injuries are challenging to detect and distinguish from sterile inflammation. Here we present the combined first-time application of a bacteria-targeted positron emission tomogra…
View article: Bacteria-targeted imaging using vancomycin-based positron emission tomography tracers can distinguish infection from sterile inflammation
Bacteria-targeted imaging using vancomycin-based positron emission tomography tracers can distinguish infection from sterile inflammation Open
View article: Vancomycin-based tracers for bacteria-targeted imaging of infection
Vancomycin-based tracers for bacteria-targeted imaging of infection Open
Bacterial infections are a major problem in virtually all medical disciplines. These infections are often misdiagnosed or mistreated, which can result in severe complications like prolonged hospitalization, loss of limbs, or even death. Cu…
View article: Synthesis and preclinical evaluation of novel 18F-vancomycin-based tracers for the detection of bacterial infections using positron emission tomography
Synthesis and preclinical evaluation of novel 18F-vancomycin-based tracers for the detection of bacterial infections using positron emission tomography Open
View article: Ultrafast Photoclick Reaction for Selective <sup>18</sup>F-Positron Emission Tomography Tracer Synthesis in Flow
Ultrafast Photoclick Reaction for Selective <sup>18</sup>F-Positron Emission Tomography Tracer Synthesis in Flow Open
The development of very fast, clean, and selective methods for indirect labeling in PET tracer synthesis is an ongoing challenge. Here we present the development of an ultrafast photoclick method for the synthesis of short-lived 18