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View article: Staging laparoscopy to detect occult metastases in localized pancreatic cancer: global survey among nine international societies
Staging laparoscopy to detect occult metastases in localized pancreatic cancer: global survey among nine international societies Open
Despite considerable global variability, SL is widely used to detect occult metastases in pancreatic cancer, mainly in high-risk patients and often during the scheduled laparotomy. The observed variability highlights the need for more evid…
View article: 10-year survival after resection of pancreatic ductal adenocarcinoma with pathological re-examination of a nationwide cohort
10-year survival after resection of pancreatic ductal adenocarcinoma with pathological re-examination of a nationwide cohort Open
The observed 10-year OS after resection of PDAC in a nationwide cohort was only 5.3 % after pathological re-examination.
View article: Nationwide outcomes of 1000 robotic pancreatoduodenectomies across the four phases of the learning curve
Nationwide outcomes of 1000 robotic pancreatoduodenectomies across the four phases of the learning curve Open
Background Robotic pancreatoduodenectomy (RPD) is increasingly being implemented to enhance patient recovery, but it is unclear what happens to patient outcomes after the initial learning curve. The aim of this study was to evaluate the fi…
View article: Minimally Invasive vs Open Left Pancreatectomy for Resectable Pancreatic Cancer
Minimally Invasive vs Open Left Pancreatectomy for Resectable Pancreatic Cancer Open
Importance The DIPLOMA trial showed comparable radical resection rates after minimally invasive left pancreatectomy (MILP) and open left pancreatectomy (OLP) in patients with upfront resectable pancreatic cancer. Data on long-term overall …
View article: Short- and long-term outcomes after venous resection during left-sided and total pancreatic resection: a nationwide cohort study
Short- and long-term outcomes after venous resection during left-sided and total pancreatic resection: a nationwide cohort study Open
Our findings suggest that, despite technical impediments of VR during LPR, switching to TP may not benefit patients.
View article: CHOLANGIOCARCINOMA IN INDIVIDUALS WITH CHRONIC LIVER DISEASE IS DIAGNOSED EARLIER, LEADING TO BETTER PROGNOSIS
CHOLANGIOCARCINOMA IN INDIVIDUALS WITH CHRONIC LIVER DISEASE IS DIAGNOSED EARLIER, LEADING TO BETTER PROGNOSIS Open
Introduction and Objectives: Cholangiocarcinoma (CCA) incidence and mortality are rising globally. Chronic liver diseases (CLD) are recognized risk factors. This study aimed to compare the clinical presentation and outcomes of CCA in patie…
View article: Outcomes following exploratory surgery without subsequent resection in perihilar cholangiocarcinoma: A nationwide analysis
Outcomes following exploratory surgery without subsequent resection in perihilar cholangiocarcinoma: A nationwide analysis Open
Among patients with non-metastatic pCCA receiving systemic therapy, survival outcomes are comparable between those who undergo surgical exploration and those who do not. Despite a possible impact on quality of life, these findings suggest …
View article: Characteristics of “Very Early” Intrahepatic Cholangiocarcinoma Undergoing Liver Resection and Its Relationship With Carbohydrate Antigen 19‐9
Characteristics of “Very Early” Intrahepatic Cholangiocarcinoma Undergoing Liver Resection and Its Relationship With Carbohydrate Antigen 19‐9 Open
Introduction The concept of “very early” ICC ( ≤ 2 cm, single tumor) has been introduced in the context of LT. Due to the limited number of patients in this subset, the characteristics and long‐term outcomes have been ill‐defined. We sough…
View article: Surgical Complications in Patients with (borderline) Resectable Pancreatic Cancer after Neoadjuvant Therapy in the PREOPANC-2 Randomized Controlled Trial
Surgical Complications in Patients with (borderline) Resectable Pancreatic Cancer after Neoadjuvant Therapy in the PREOPANC-2 Randomized Controlled Trial Open
Objective: To compare the incidence of major surgical complications between patients with (borderline) resectable pancreatic cancer treated with neoadjuvant FOLFIRINOX versus neoadjuvant gemcitabine-based chemoradiotherapy. Summary of Back…
View article: The Brescia International Multidisciplinary Consensus Guidelines on the Optimal Pathology Assessment and Multidisciplinary Pathways of Non‐Pancreatic Neoplasms in and Around the Ampulla of Vater (PERIPAN)
The Brescia International Multidisciplinary Consensus Guidelines on the Optimal Pathology Assessment and Multidisciplinary Pathways of Non‐Pancreatic Neoplasms in and Around the Ampulla of Vater (PERIPAN) Open
Importance The lack of multidisciplinary workflow guidelines and clear definitions and classifications for neoplasms in and around the ampulla of Vater results in inconsistencies affecting patient care and research. Objective The PERIPAN i…
View article: Bile spillage in incidental gallbladder cancer is not an independent predictor for survival: A multi-institute retrospective cohort study
Bile spillage in incidental gallbladder cancer is not an independent predictor for survival: A multi-institute retrospective cohort study Open
BACKGROUND Bile spillage occurs more frequently in patients with incidental gallbladder carcinoma (iGBC) and may be associated with poor survival due to presumed high risk of peritoneal seeding. AIM To investigate the impact of bile spilla…
View article: Oncological outcome after robot-assisted <i>versus</i> open pancreatoduodenectomy for upfront resectable cancer in the pancreatic head: a nationwide cohort analysis
Oncological outcome after robot-assisted <i>versus</i> open pancreatoduodenectomy for upfront resectable cancer in the pancreatic head: a nationwide cohort analysis Open
Background Robot-assisted pancreatoduodenectomy (RPD) aims to enhance postoperative recovery compared to open pancreatoduodenectomy (OPD). Although recent randomized trials confirmed the short-term safety of RPD, they did not confirm super…
View article: STRONG II trial: stereotactic body radiation therapy following chemotherapy for unresectable perihilar cholangiocarcinoma – a single-arm multicentre phase II study
STRONG II trial: stereotactic body radiation therapy following chemotherapy for unresectable perihilar cholangiocarcinoma – a single-arm multicentre phase II study Open
Introduction For patients with perihilar cholangiocarcinoma (pCCA), surgical resection remains the sole treatment modality that can potentially result in cure. Unfortunately, the majority of patients present with unresectable tumours or ar…
View article: Resectability stages of pancreatic cancer: nationwide reference
Resectability stages of pancreatic cancer: nationwide reference Open
Contains fulltext : 320988.pdf (Publisher’s version ) (Open Access)
View article: Robot-assisted and Laparoscopic Extended Left Pancreatectomy
Robot-assisted and Laparoscopic Extended Left Pancreatectomy Open
Objective: To compare postoperative outcomes after extended robot-assisted left pancreatectomy (e-RLP) and extended laparoscopic left pancreatectomy (e-LLP). Summary Background Data: The implementation of RLP is increasing worldwide with e…
View article: Lymphocyte‐C‐Reactive Protein Ratio: Impact on Prognosis of Patients Following Resection of Primary Liver Cancer
Lymphocyte‐C‐Reactive Protein Ratio: Impact on Prognosis of Patients Following Resection of Primary Liver Cancer Open
Objective We sought to characterize the prognostic value of lymphocyte‐C‐reactive protein ratio (LCR) among patients undergoing liver resection (LR) for hepatocellular carcinoma (HCC) and intrahepatic cholangiocarcinoma (ICC). Methods Pati…
View article: Refinement of histologic subtypes and identification of biomarkers linked to unfavorable prognosis in cholangiocarcinoma: The ENSCCA registries’ framework for digital twin advancement
Refinement of histologic subtypes and identification of biomarkers linked to unfavorable prognosis in cholangiocarcinoma: The ENSCCA registries’ framework for digital twin advancement Open
Background and Aims: Cholangiocarcinoma (CCA) displays remarkable anatomical and histological heterogeneity. Besides diagnosis confirmation, histology currently does not have a major role in the management of CCA. We aimed to study the cli…
View article: Endoscopic ultrasound with tissue acquisition of lymph nodes in patients with resectable distal cholangiocarcinoma
Endoscopic ultrasound with tissue acquisition of lymph nodes in patients with resectable distal cholangiocarcinoma Open
Preoperative EUS had a limited but clinically important yield for nodal staging in patient with presumed resectable dCCA but was not executed in systematic fashion. Further prospective studies should investigate whether systematic nodal st…
View article: Routine Imaging After Resection of Pancreatic Ductal Adenocarcinoma
Routine Imaging After Resection of Pancreatic Ductal Adenocarcinoma Open
Objective: To evaluate the utilization of routine imaging and the impact on survival after resection of pancreatic ductal adenocarcinoma (PDAC). Background: Evidence on the benefit of routine imaging after resection of PDAC on early detect…
View article: Primary percutaneous stenting above the ampulla versus endoscopic drainage for unresectable malignant hilar biliary obstruction (TESLA RCT): study protocol for a multicenter randomized controlled trial
Primary percutaneous stenting above the ampulla versus endoscopic drainage for unresectable malignant hilar biliary obstruction (TESLA RCT): study protocol for a multicenter randomized controlled trial Open
Background Patients with malignant hilar biliary obstruction typically present with painless jaundice. They commonly have perihilar cholangiocarcinoma (pCCA), but also intrahepatic cholangiocarcinoma, gallbladder cancer, and metastases to …