Azza Gaber Antar Farag
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View article: A Non-Inferiority Clinical Trial Comparing Probiotics and Oral Corticosteroids for the Management of Acute Exacerbation of Atopic Dermatitis Patients
A Non-Inferiority Clinical Trial Comparing Probiotics and Oral Corticosteroids for the Management of Acute Exacerbation of Atopic Dermatitis Patients Open
A prospective controlled pilot study on the feasibility of utilization of a probiotic mixture for management of acute exacerbation of atopic dermatitis (AD). Patients were allocated to either standard of care (SOC) therapy with tapering do…
View article: Circadian clock gene expression and polymorphism in non-segmental vitiligo
Circadian clock gene expression and polymorphism in non-segmental vitiligo Open
Background Vitiligo is an acquired and progressive mucocutaneous disease with the damage of functioning epidermal melanocytes. Metabolic syndrome is associated with inflammatory skin diseases incorporating vitiligo. The circadian dysfuncti…
View article: Adiponectin serum levels and ADIPOQ (rs2241766) polymorphism in alopecia areata Egyptian patients
Adiponectin serum levels and ADIPOQ (rs2241766) polymorphism in alopecia areata Egyptian patients Open
ADIPOQ (rs2241766) gene polymorphism (TG genotype and G allele) may modulate AA risk and contribute to the development of AA in Egyptian populations. Decreased circulating adiponectin levels may have a dynamic role in AA etiopathogenesis. …
View article: The Incidence and Molecular Characterization of Banana Bunchy Top Virus (BBTV) Infecting Banana (Musa spp.) in Ismailia governorate, Egypt
The Incidence and Molecular Characterization of Banana Bunchy Top Virus (BBTV) Infecting Banana (Musa spp.) in Ismailia governorate, Egypt Open
The banana is the most important fruit in Egypt.Banana bunchy top disease, caused by the banana bunchy top virus (BBTV), is one of the most damaging infections on banana plantations, resulting in significant crop losses.The current study w…
View article: YKL-40 Serum Level in COVID-19 Patients Having Skin Manifestations
YKL-40 Serum Level in COVID-19 Patients Having Skin Manifestations Open
Objectives: To measure the level of YKL-40 in COVID-19 patients with and without skin lesion in Elbagour Hospital.
View article: Dermatological Manifestations Associated with Covid-19 Patients in Elbagour General Hospital, El-Menoufia Governorate
Dermatological Manifestations Associated with Covid-19 Patients in Elbagour General Hospital, El-Menoufia Governorate Open
Background: Corona virus-19 disease (COVID-19) marked the beginning of a new pandemic COVID-19 after massive numbers of acute pneumonia with unknown origin.Some COVID-19 confirmed patients experienced some skin lesions that might be a clin…
View article: Circulating ghrelin and apelin levels in nonobese psoriasis vulgaris patients
Circulating ghrelin and apelin levels in nonobese psoriasis vulgaris patients Open
Background The metabolism and immune system are linked via a network of many mediators known as adipokines. Ghrelin and apelin-36 are unique adipokines; however, their role in psoriasis, an immune-mediated disease, remains unclear. Objecti…
View article: The clinical and pathological effectiveness of microneedling and topical 5‐fluorouracil in vitiligo treatment: An association with matrix metalloproteinase 2 immunohistochemical expression
The clinical and pathological effectiveness of microneedling and topical 5‐fluorouracil in vitiligo treatment: An association with matrix metalloproteinase 2 immunohistochemical expression Open
Background The current therapies for vitiligo require long duration with often disappointing outcomes. 5‐Fluorouracil (5‐FU) is a chemotherapeutic agent approved for topical use in the treatment of several dermatologic conditions. Matrix m…
View article: The Role of TROP2 in BCC and Cutaneous SCC: A Clinical and Immunohistochemical Study
The Role of TROP2 in BCC and Cutaneous SCC: A Clinical and Immunohistochemical Study Open
TROP2 could have an important role in BCC and SCC pathogenesis. TROP2 targeting may have appraising effect in clinical application in BCC and SCC management.
View article: Methimazole in the Treatment of Melasma: A Clinical and Dermascopic Study.
Methimazole in the Treatment of Melasma: A Clinical and Dermascopic Study. Open
BACKGROUND: Melasma is a chronic hypermelanotic disorder that is challenging to treat; no single effective therapeutic agent for it has been discovered. Methimazole, an oral antithyroid drug, has a skin depigmenting effect when used topica…
View article: <p>Neuronal Precursor Cell Expressed Developmentally Down Regulated 4 (NEDD4) Gene Polymorphism Contributes to Keloid Development in Egyptian Population</p>
Neuronal Precursor Cell Expressed Developmentally Down Regulated 4 (NEDD4) Gene Polymorphism Contributes to Keloid Development in Egyptian Population Open
The polymorphism of the NEDD4 gene rs8032158 could participate in the formation of keloids in the Egyptian population. The NEDD4 rs8032158 CC genotype may have a role in keloid severity.
View article: Effect of Physicochemical Parameters on Inorganic Phosphate Solubilisation by Serratia marcescens PH1 and Organic Acids Production
Effect of Physicochemical Parameters on Inorganic Phosphate Solubilisation by Serratia marcescens PH1 and Organic Acids Production Open
P HOSPHATE solubilizing bacteria are capable to release inorganic phosphate and make it available to plants for growth enhancement.In this study, Serratia marcescens PH1, which has been isolated from tomato plant rhizosphere, has been subj…
View article: <p>Relationship Between sCD163 and mCD163 and Their Implication in the Detection and Typing of Leprosy</p>
Relationship Between sCD163 and mCD163 and Their Implication in the Detection and Typing of Leprosy Open
Both sCD163 and mCD163 positive monocytes may have an active role in leprosy pathogenesis. They could be potential biomarkers for leprosy detection and typing.
View article: <p>Role of Galectin-9 in Atopic Dermatitis — Is It Mediated Through E Selectin? A Clinical and Immunohistochemical Study</p>
Role of Galectin-9 in Atopic Dermatitis — Is It Mediated Through E Selectin? A Clinical and Immunohistochemical Study Open
Galectin-9 and E selectin participates independently in atopic dermatitis pathogenesis, that may help in development of new therapeutic agents in atopic dermatitis management program.
View article: Low risk and High risk HPV Genotypes in Skin Tags
Low risk and High risk HPV Genotypes in Skin Tags Open
Background: Skin tags are flesh-coloured, pedunculated growths with a smooth surface, reported to have an incidence of 46% of the general population.The etiology of skin tags is still unknown, human papillomavirus skin infection is one of …
View article: Leucine-rich glioma inactivated 3: a novel keratinocyte-derived melanogenic cytokine in vitiligo patients
Leucine-rich glioma inactivated 3: a novel keratinocyte-derived melanogenic cytokine in vitiligo patients Open
Decreased LGI3 protein may play an active role in vitiligo pathogenesis and its up-regulation after NB-UVB phototherapy, may actively participate in NB-UVB photo-induced melanogenesis.
View article: <p>Immunohistochemical study of janus kinase 1/signal transducer and activator of transcription 3 in psoriasis vulgaris</p>
Immunohistochemical study of janus kinase 1/signal transducer and activator of transcription 3 in psoriasis vulgaris Open
Background: Human JAKs are responsible for generating docking sites for human SSTAT phosphorylation. The role of JAKs in psoriasis pathogenesis has not been clearly explained. Aim: To investigate the role of JAK1 in psoriasis pathogenesis …
View article: Interleukin-6 serum level and gene polymorphism in keloid patients
Interleukin-6 serum level and gene polymorphism in keloid patients Open
The formation of keloid is associated with accumulation of extracellular matrix (ECM) formed mainly of collagen and fibronectin. Persistent deregulated IL-6 synthesis causes the development of various diseases. This study aim to investigat…
View article: <p>Role of insulin-like growth factor-1 in skin tags: a clinical, genetic and immunohistochemical study in a sample of Egyptian patients</p>
Role of insulin-like growth factor-1 in skin tags: a clinical, genetic and immunohistochemical study in a sample of Egyptian patients Open
Background: Skin tags (STs) are benign connective tissue neoplasms, in which insulin-like growth factor -1 (IGF-1) has a mitogenic and antiapoptotic activity. Purpose: We aimed to study for the first time, the possible role of IGF-1 (CA) 1…
View article: <p>Role of 11&beta; HSD 1, rs12086634, and rs846910 single-nucleotide polymorphisms in metabolic-related skin diseases: a clinical, biochemical, and genetic study</p>
Role of 11β HSD 1, rs12086634, and rs846910 single-nucleotide polymorphisms in metabolic-related skin diseases: a clinical, biochemical, and genetic study Open
11β-HSD1 rs846910 and rs12086634 gene polymorphisms may contribute to AV and STs pathogenesis, that may be mediated through enhancing the enzymatic activity (increasing cortisol levels). AV and STs are associated with obesity and atherogen…
View article: Role of HCV Infection in Psoriasis: A Clinical and Immunohistochemical Study
Role of HCV Infection in Psoriasis: A Clinical and Immunohistochemical Study Open
Introduction: Psoriasis is a common inflammatory skin disorder in which different infections play an important role in its pathogenesis. It was proposed that Hepatitis C Virus (HCV) is involved in psoriasis pathogenesis, and may contribute…
View article: Second to fourth digit ratio in female patients with acne vulgaris: Could it be a predictor of androgen receptor status?
Second to fourth digit ratio in female patients with acne vulgaris: Could it be a predictor of androgen receptor status? Open
A masculine second to fourth digit ratio in female patients could anticipate acne vulgaris development, its duration and severity. Moreover, this ratio is associated with an upregulation of cutaneous androgen receptors. Taken together, sec…
View article: Macrophage migration inhibitory factor as an incriminating agent in vitiligo
Macrophage migration inhibitory factor as an incriminating agent in vitiligo Open
Migration inhibitory factor may have an active role in the development of vitiligo, and it may also be a useful index of disease severity. Consequently, migration inhibitory factor may be a new treatment target for vitiligo patients.
View article: Phosphate Solubilization by &lt;i&gt;Bacillus subtilis&lt;/i&gt; and &lt;i&gt;Serratia marcescens&lt;/i&gt; Isolated from Tomato Plant Rhizosphere
Phosphate Solubilization by <i>Bacillus subtilis</i> and <i>Serratia marcescens</i> Isolated from Tomato Plant Rhizosphere Open
Plants need phosphorus for many physiological activities in a form of phosphate anions. Three different bacterial strains (Bacillus subtilis PH, Serratia marcescens PH1, and Serratia marcescens PH2), recently isolated from tomato plant rhi…
View article: IL-8 mRNA and Serum Levels in Vitiligo Patients: A Case Control Study
IL-8 mRNA and Serum Levels in Vitiligo Patients: A Case Control Study Open
Introduction: Many theories are suggested to explain aetiology of vitiligo, such as autoimmune, genetic and biochemical. Interleukin-8 (IL-8) is a pro-inflammatory chemokine which is evaluated in the pathogenesis of some skin diseases, lik…