Explanipedia

Regulation of adipogenesis by nucleotides Open

Julia A. Pinette, Heather Bryant, Jacob W. Myers, Elma Zaganjor · 2025

The process by which multipotent cells commit to differentiate into distinct cell types, eventually forming functional tissues and organisms, has fascinated scientists for decades. Consequently, numerous studies have contributed to our und…

Disruption of nucleotide biosynthesis reprograms mitochondrial metabolism to inhibit adipogenesis Open

Julia A. Pinette, Jacob W. Myers, Woo Yong Park, Heather Bryant, Alex M. Eddie , et al. · 2024

Opportunistic salpingectomy between 2011 and 2016: a descriptive analysis Open

Gillian E. Hanley, Jin Niu, Jihee Han, Sharon Fung, Heather Bryant , et al. · 2022

The rates of OS increased between 2011 and 2016, but there was considerable variation across the included jurisdictions. Our study indicates room for rates of OS to increase across many of the included jurisdictions.

Population-Based Cancer Survival in Canada and the United States by Socioeconomic Status: Findings from the CONCORD-2 Study. Open

Hannah K. Weir, Heather Bryant, Donna Turner, Michel P. Coleman, Angela B. Mariotto , et al. · 2022

Among younger Canadian cancer patients in the lowest SES group, greater access to health care may have resulted in higher cancer survival, while higher screening prevalence and access to health insurance (Medicare) among older Americans du…

Breast Density and Risk of Interval Cancers: The Effect of Annual Versus Biennial Screening Mammography Policies in Canada Open

Jean M. Seely, Susan Peddle, Huiming Yang, Anna M. Chiarelli, Megan K. McCallum , et al. · 2021

Regular screening mammography reduces breast cancer mortality. However, in women with dense breasts, the performance of screening mammography is reduced, which is reflected in higher interval cancer rates (ICR). In Canada, population-based…

From evaluation of joint programmes to joint evaluation of SDGs-ready interventions Open

Carlo Carugi, Heather Bryant · 2021

This chapter broadens the discussion on the opportunities and challenges of evaluating environment joint programmes by introducing the opportunities and challenges of conducting joint evaluations in the Sustainable Development Goals (SDGs)…

The Cost of Failed First-Line Cancer Treatment Related to Continued Smoking in Canada Open

Nicolas Iragorri, Beverley M. Essue, Caitlyn Timmings, Deb Keen, Heather Bryant , et al. · 2020

Background: Smoking by cancer patients and survivors causes adverse cancer treatment outcomes, but little information is available about how smoking can affect cancer treatment costs. Methods: We developed a model to estimate attributable …

Management of screen-detected lung nodules: A Canadian partnership against cancer guidance document Open

Stephen Lam, Heather Bryant, Laura Donahoe, Ashleigh Domingo, Craig C. Earle , et al. · 2020

RATIONALE: Appropriate management of low-dose computed tomography (LDCT) screening detected lung nodules will have significant implications for health care resource utilization and minimizing harm from radiation exposure related to imaging…

New approaches to cancer care in a COVID-19 world Open

John Butler, Christian Finley, Charles Norell, Samantha Harrison, Heather Bryant , et al. · 2020

Progress in cancer survival, mortality, and incidence in seven high-income countries 1995–2014 (ICBP SURVMARK-2): a population-based study Open

Melina Arnold, Mark J. Rutherford, Aude Bardot, Jacques Ferlay, Therése Andersson , et al. · 2019

Moving toward the Elimination of Cervical Cancer: Modelling the Health and Economic Benefits of Increasing Uptake of Human Papillomavirus Vaccines Open

Alison Smith, Nicola Baines, S. Memon, Natalie Fitzgerald, J. Chadder , et al. · 2019

Background: The human papillomavirus (HPV) is a common sexually transmitted infection and a primary cause of cervical cancer. The Government of Canada has set a target of reaching 90% HPV vaccine coverage among adolescents by 2025. Here, w…

Progress in cancer control: survival, mortality and incidence in seven high-income countries 1995-2014 (the ICBP SURVMARK-2 project) Open

Melina Arnold, Mark J. Rutherford, Aude Bardot, Jacques Ferlay, Therése Andersson , et al. · 2019

Malignant primary brain and other central nervous system tumors diagnosed in Canada from 2009 to 2013 Open

Emily Walker, Faith G. Davis, Amanda Shaw, R. Louchini, Lorrains Shack , et al. · 2018

These data represent an initial detailed report on the frequency and distribution of primary malignant brain and other CNS tumors diagnosed in the Canadian population in 2009-2013. The reported distributions of tumor diagnoses by sex and a…

Acute Care Hospitalization Near the End of Life for Cancer Patients Who Die in Hospital in Canada Open

K. DeCaria, Deborah Dudgeon, E. Green, Raquel Shaw Moxam, Rami Rahal , et al. · 2017

Acute care hospitals have a role in managing the health care needs of people affected by cancer when they are at the end of life. However, there is a need to provide end-of-life care in other settings, including at home or in hospice, when…

Choosing Wisely in Cancer Control across Canada—A Set of Baseline Indicators Open

Kim Tran, Rami Rahal, S. Fung, Gina Lockwood, C. Louzado , et al. · 2017

Value-based care, which balances high-quality care with the most efficient use of resources, has been considered the next frontier in cancer care and a means to maintain health system sustainability. Created to promote value-based care, Ch…

How Different Is Cancer Control across Canada? Comparing Performance Indicators for Prevention, Screening, Diagnosis, and Treatment Open

Rami Rahal, J. Chadder, K. DeCaria, Gina Lockwood, Heather Bryant · 2017

Meaningful performance measures are an important part of the toolkit for health system improvement. The Canadian Partnership Against Cancer has been reporting on pan-Canadian cancer system performance indicators since 2009—work that has le…

Controlled Settings for Lung Cancer Screening: Why Do They Matter? Considerations for Referring Clinicians Open

Aamir Bharmal, A. Crosskill, Stephen Lam, Heather Bryant · 2016

The updated guideline on lung cancer screening released in March 2016 by the Canadian Task Force on Preventive Health Care recommends screening for people at high risk for lung cancer.[...]

Use of Low-Value Radiotherapy Practices in Canada: An Analysis of Provincial Cancer Registry Data Open

Kim Tran, Rami Rahal, Michael Brundage, S. Fung, C. Louzado , et al. · 2016

Background: As part of Choosing Wisely Canada (a national campaign to encourage patient–provider conversations about unnecessary medical tests, treatments, and procedures), a list of ten oncology practices that could be low-value in some i…

Smoking Behaviours of Current Cancer Patients in Canada Open

J. Liu, J. Chadder, S. Fung, Gina Lockwood, Rami Rahal , et al. · 2016

Evidence shows that continued smoking by cancer patients leads to adverse treatment outcomes and affects survival. Smoking diminishes treatment effectiveness, exacerbates side effects, and increases the risk of developing additional compli…

Patterns of Care and Treatment Trends for Canadian Men with Localized Low-Risk Prostate Cancer: An Analysis of Provincial Cancer Registry Data Open

Kim Tran, Rami Rahal, S. Fung, C. Louzado, Geoffrey A. Porter , et al. · 2016

Background: Many prostate cancers (pcas) are indolent and, if left untreated, are unlikely to cause death or morbidity in a man’s lifetime. As a result of testing for prostate-specific antigen, more such cases are being identified, leading…

Original Canadian Cancer Costing Research for Cancer Control Sustainability, Quality, and Value Open

Heather Bryant · 2016

Given the acute shortage of Canada-specific cancer health economics evidence, [...]

Treatment Patterns among Canadian Men Diagnosed with Localized Low-Risk Prostate Cancer Open

Carolyn Sandoval, Kim Tran, Rami Rahal, Geoffrey A. Porter, S. Fung , et al. · 2015

In general, guideline-recommended treatment options for men with low-risk prostate cancer (pca) include active surveillance, radical prostatectomy, and external-beam radiation therapy or brachytherapy. Because of the concern about overdiag…

Wait Times for Prostate Cancer Treatment and Patient Perceptions of Care in Canada: A Mixed-Methods Report Open

Kim Tran, Carolyn Sandoval, Rami Rahal, Geoff Porter, Robert Siemens , et al. · 2015

Background: Access to cancer care is a significant concern for Canadians. Prolonged delays between cancer diagnosis and treatment have been associated with anxiety, stress, and perceived powerlessness for patients and their family members.…

Recent Trends in Breast, Cervical, and Colorectal Cancer Screening Test Utilization in Canada, Using Self-Reported Data from 2008 and 2012 Open

Diane Major, David Armstrong, Heather Bryant, Winson Y. Cheung, Kathleen Decker , et al. · 2015

In Canada, self-reported data from the Canadian Community Health Survey 2008 and 2012 provide an opportunity to examine overall utilization of breast, cervical, and colorectal cancer screening tests for both programmatic and opportunistic …

Rectal Cancer Resection and Circumferential Margin Rates in Canada: A Population-Based Study Open

K. DeCaria, Rami Rahal, Jin Niu, Gina Lockwood, Heather Bryant · 2015

INTRODUCTION [...]

Heather Bryant YOU? Author Swipe