Giampaolo Perna
YOU?
Author Swipe
View article: Performance evaluation of a novel screening tool for depressive episodes in COMISA: a comparative analysis with standard neuropsychometric assessments
Performance evaluation of a novel screening tool for depressive episodes in COMISA: a comparative analysis with standard neuropsychometric assessments Open
Introduction Insomnia and obstructive sleep apnea (OSA) are each linked to elevated risks of depression. When comorbid (COMISA), these risks increase further, highlighting the need for effective depression screening. This study evaluated t…
View article: Uncovering hidden depression: the critical role of depression screening in sleep disorders at U.S. sleep centers
Uncovering hidden depression: the critical role of depression screening in sleep disorders at U.S. sleep centers Open
Introduction Depression and sleep disorders are strongly linked, with sleep centers (SCs) reporting depressive symptoms in up to 63% of patients and depression diagnoses in 22%. Despite this, routine depression screening is not standard in…
View article: Exploring Heart Rate Variability Changes Following Respiratory Training in Individuals with Panic Disorder
Exploring Heart Rate Variability Changes Following Respiratory Training in Individuals with Panic Disorder Open
Introduction Studies reported an association between panic disorder (PD) and diminished heart rate variability (HRV) (Zhang et al. J Affect Disord 2020; 15, 267 297-306), potentially heightening their susceptibility to cardiovascular morta…
View article: The Impact of Panic Disorder on Severe Asthma and Chronic Rhinosinusitis with Nasal Polyps: A Comparative Clinical Profile Study
The Impact of Panic Disorder on Severe Asthma and Chronic Rhinosinusitis with Nasal Polyps: A Comparative Clinical Profile Study Open
Introduction Severe asthma (SA), often associated with chronic rhinosinusitis with nasal polyps (CRSwNP), contributes significantly to global disability and mortality. A personalized treatment approach, including addressing treatable trait…
View article: The Influence of Individual Characteristics, Personality Traits, and Life Events on Academic Stress: A Survey among Third-Year Medical Students at Humanitas University
The Influence of Individual Characteristics, Personality Traits, and Life Events on Academic Stress: A Survey among Third-Year Medical Students at Humanitas University Open
Introduction Medical students face a demanding academic journey, where stress can significantly impact their well-being and performance. Both personal and environmental factors contribute to this burden, yet research on academic stress in …
View article: Family Connections: The Impact of an Education Program for Carers of Individuals With Borderline Personality Disorder in Italian Mental Health Services
Family Connections: The Impact of an Education Program for Carers of Individuals With Borderline Personality Disorder in Italian Mental Health Services Open
Borderline personality disorder (BPD) has a strong impact not only on patients' lives but also on their families. The presence of an invalidating environment is one of the key factors in the etiology of BPD. This study evaluated the impact…
View article: Foundations for a Personalized Psycho-Oncology: The State of the Art
Foundations for a Personalized Psycho-Oncology: The State of the Art Open
Personalized psycho-oncology represents a major challenge for the holistic care of cancer patients. It focuses on individualized psychotherapeutic and psychiatric interventions to address specific psychological needs. This narrative review…
View article: How to treat subsyndromal anxiety disorder – practical recommendations for implementation in primary care
How to treat subsyndromal anxiety disorder – practical recommendations for implementation in primary care Open
Implementing these recommendations in primary care can lead to effective treatment of SSA, preventing the development of more severe anxiety disorders. An integrative approach, combining lifestyle modifications, psychotherapy, and pharmaco…
View article: CARDIAC CT–PERFUSION IMAGING IN MYOCARDIAL BRIDGING EVALUATION: A NOVEL WEAPON FOR NON–INVASIVE ASSESSMENT OF A SILENT KILLER
CARDIAC CT–PERFUSION IMAGING IN MYOCARDIAL BRIDGING EVALUATION: A NOVEL WEAPON FOR NON–INVASIVE ASSESSMENT OF A SILENT KILLER Open
Introduction Myocardial bridging (MB) is a congenital anomaly characterized by the intramyocardial course of one or more coronary arteries that provokes endothelial dysfunction and can generate myocardial ischemia with its pathological con…
View article: HUGE EPICARDIAL LIPOMATOSIS AND BUTTERFLY APEX OF THE RIGHT VENTRICLE: DIAGNOSITC PITFALLS IN A PATIENT REFERRED FOR SUSPECTED ARRHYTHMOGENIC RIGHT VENTRICULAR CARDIOMYOPATHY
HUGE EPICARDIAL LIPOMATOSIS AND BUTTERFLY APEX OF THE RIGHT VENTRICLE: DIAGNOSITC PITFALLS IN A PATIENT REFERRED FOR SUSPECTED ARRHYTHMOGENIC RIGHT VENTRICULAR CARDIOMYOPATHY Open
A 68–year–old woman affected by dyslipidemia had a clinical history notable for T wave inversion (TWI) in the lateral and precordial leads from 2008, with a normal echocardiogram (TTE) and a normal coronary angiogram in 2009. No family his…
View article: MITRACLIP TREATMENT FOR CARDIOGENIC SHOCK DUE TO ACUTE MITRAL REGURGITATION IN A PATIENT WITH POSTINFARCTION PAPILLARY MUSCLE RUPTURE
MITRACLIP TREATMENT FOR CARDIOGENIC SHOCK DUE TO ACUTE MITRAL REGURGITATION IN A PATIENT WITH POSTINFARCTION PAPILLARY MUSCLE RUPTURE Open
A 85–year–old woman presented to ED with worsening dyspnea for 24 hours; no other related symptom. Her medical history included hypertension, dyslipidemia, type 2 DM and surgical coronary revascularization 13 years before for multiple crit…
View article: LMNA–RELATED DILATED CARDIOMYOPATHY PRESENTING WITH REGIONAL WALL AKINESIS AND TRANSMURAL LATE GADOLINIUM ENHANCEMENT
LMNA–RELATED DILATED CARDIOMYOPATHY PRESENTING WITH REGIONAL WALL AKINESIS AND TRANSMURAL LATE GADOLINIUM ENHANCEMENT Open
A 26–year–old girl was admitted at hospital in December 2022 for a syncopal episode. She referred fatigue and dyspnea in the last 2 months. EKG was markedly abnormal showing peripheral low voltages, poor R wave progression in prechordial l…
View article: The definition of treatment resistance in anxiety disorders: a Delphi method‐based consensus guideline
The definition of treatment resistance in anxiety disorders: a Delphi method‐based consensus guideline Open
Anxiety disorders are very prevalent and often persistent mental disorders, with a considerable rate of treatment resistance which requires regulatory clinical trials of innovative therapeutic interventions. However, an explicit definition…
View article: Enhanced sleep staging with artificial intelligence: a validation study of new software for sleep scoring
Enhanced sleep staging with artificial intelligence: a validation study of new software for sleep scoring Open
Manual sleep staging (MSS) using polysomnography is a time-consuming task, requires significant training, and can lead to significant variability among scorers. STAGER is a software program based on machine learning algorithms that has bee…
View article: Clinical outcomes and predictors of success with Impella weaning in cardiogenic shock: a single-center experience
Clinical outcomes and predictors of success with Impella weaning in cardiogenic shock: a single-center experience Open
Introduction Cardiogenic shock (CS) is a severe syndrome with poor prognosis. Short-term mechanical circulatory support with Impella devices has emerged as an increasingly therapeutic option, unloading the failing left ventricle (LV) and i…
View article: Depression, Stress and Anxiety among Women and Men Affected by Recurrent Pregnancy Loss (RPL): A Systematic Review and Meta-Analysis
Depression, Stress and Anxiety among Women and Men Affected by Recurrent Pregnancy Loss (RPL): A Systematic Review and Meta-Analysis Open
The aim of the present study is to perform a systematic review and meta-analysis on depression, stress and anxiety in women who experienced recurrent pregnancy loss (RPL) compared to controls and to men who experienced RPL. The pooled resu…
View article: P150 STRESS–REST DYNAMIC–CT MYOCARDIAL PERFUSION IMAGING IN THE MANAGEMENT OF MYOCARDIAL BRIDGING: A “ONE–STOP SHOP” EXAM
P150 STRESS–REST DYNAMIC–CT MYOCARDIAL PERFUSION IMAGING IN THE MANAGEMENT OF MYOCARDIAL BRIDGING: A “ONE–STOP SHOP” EXAM Open
Myocardial bridging (MB) is a congenital anomaly characterized by intramyocardial coronary course that can cause coronary compression during systole and can lead to myocardial ischemia. The improvement in computed tomography (CT) scanner t…
View article: P336 PROCALCITONIN AS PREDICTOR OF IN–HOSPITAL MORTALITY IN A CARDIOGENIC SHOCK POPULATION: A 10–YEARS SINGLE CENTRE RETROSPECTIVE STUDY
P336 PROCALCITONIN AS PREDICTOR OF IN–HOSPITAL MORTALITY IN A CARDIOGENIC SHOCK POPULATION: A 10–YEARS SINGLE CENTRE RETROSPECTIVE STUDY Open
Background Plasmatic procalcitonin (PCT) is an acute–phase inflammatory marker, its value tends to increase during inflammatory conditions such as septic shock, cardiogenic shock (CS) and bacterial infections. Patients with CS complicating…
View article: P358 FATAL CONSPIRACY: MIDVENTRICULAR OBSTRUCTIVE HYPERTROPHIC CARDIOMYOPATHY COMPLICATED BY GIANT APICAL ANEURYSM AND SEVERE MITRAL REGURGITATION
P358 FATAL CONSPIRACY: MIDVENTRICULAR OBSTRUCTIVE HYPERTROPHIC CARDIOMYOPATHY COMPLICATED BY GIANT APICAL ANEURYSM AND SEVERE MITRAL REGURGITATION Open
This case refers to a 69–year–old woman with a history of hypertrophic cardiomyopathy (HCM) with severe mid–ventricular obstruction complicated by apical aneurysm and restrictive phenotype. This patient had no left ventricular outflow trac…
View article: C55 A GIANT PSEUDOANEURYSM OF MITRAL–AORTIC INTERVALVULAR FIBROSA PRESENTING AS RECENT–ONSET ANGINA AND CARDIAC ARREST DUE TO VENTRICULAR FIBRILLATION
C55 A GIANT PSEUDOANEURYSM OF MITRAL–AORTIC INTERVALVULAR FIBROSA PRESENTING AS RECENT–ONSET ANGINA AND CARDIAC ARREST DUE TO VENTRICULAR FIBRILLATION Open
A 66–year–old man was suddenly referred to the emergency department (ED) for an extra–hospital cardiac arrest due to ventricular fibrillation, promptly treated by a single DC shock. Four months prior, he had undergone aortic valve replacem…
View article: P83 EFFICACY AND SAFETY OF LEVOSIMENDAN IN AN ISCHEMIC CARDIOGENIC SHOCK POPULATION: A 10–YEARS SINGLE CENTRE RETROSPECTIVE STUDY
P83 EFFICACY AND SAFETY OF LEVOSIMENDAN IN AN ISCHEMIC CARDIOGENIC SHOCK POPULATION: A 10–YEARS SINGLE CENTRE RETROSPECTIVE STUDY Open
Background Levosimendan is a Ca2+–sensitizer with inodilator action able to improve cardiac contractility without increse oxygen demand. In AHF setting clinical trial and registries showed an improvement in systemic haemodynamics without a…
View article: C25 TEMPORAL TREND MORTALITY AND IN–HOSPITAL MORTALITY PREDICTORS IN AN ISCHEMIC CARDIOGENIC SHOCK POPULATION: A 10 YEARS SINGLE–CENTRE RETROSPECTIVE STUDY
C25 TEMPORAL TREND MORTALITY AND IN–HOSPITAL MORTALITY PREDICTORS IN AN ISCHEMIC CARDIOGENIC SHOCK POPULATION: A 10 YEARS SINGLE–CENTRE RETROSPECTIVE STUDY Open
Background Cardiogenic shock (CS) after acute myocardial infarction (AMI) represents the most severe form of acute heart failure (AHF) syndromes with an high rate of in–hospital mortality. Purpose describe predictors of in–hospital mortali…
View article: C62 CHALLENGING DIAGNOSIS OF A TRIPLE CARDIAC PATHOLOGY: TRANSTHYRETIN AMYLOIDOSIS WITH ASPECTS OF HYPERTROPHIC OBSTRUCTIVE CARDIOMYOPATHY AND ANOMALOUS CORONARY ARTERY
C62 CHALLENGING DIAGNOSIS OF A TRIPLE CARDIAC PATHOLOGY: TRANSTHYRETIN AMYLOIDOSIS WITH ASPECTS OF HYPERTROPHIC OBSTRUCTIVE CARDIOMYOPATHY AND ANOMALOUS CORONARY ARTERY Open
A 70 years–old man with a history of systemic hypertension and surgically treated bilateral carpal tunnel was referred for dyspnea on exertion for few months. At physical examination a systolic heart murmur exacerbated by Valsalva maneuver…
View article: Balance Rehabilitation with Peripheral Visual Stimulation in Patients with Panic Disorder and Agoraphobia: An Open-Pilot Intervention Study
Balance Rehabilitation with Peripheral Visual Stimulation in Patients with Panic Disorder and Agoraphobia: An Open-Pilot Intervention Study Open
Given the involvement of balance system abnormalities in the pathophysiology of panic disorder and agoraphobia (PD-AG), we evaluated initial evidence for feasibility, acceptability, and potential clinical usefulness of 10 sessions of balan…
View article: Cardiorespiratory Assessments in Panic Disorder Facilitated by Wearable Devices: A Systematic Review and Brief Comparison of the Wearable Zephyr BioPatch with the Quark-b2 Stationary Testing System
Cardiorespiratory Assessments in Panic Disorder Facilitated by Wearable Devices: A Systematic Review and Brief Comparison of the Wearable Zephyr BioPatch with the Quark-b2 Stationary Testing System Open
Abnormalities in cardiorespiratory measurements have repeatedly been found in patients with panic disorder (PD) during laboratory-based assessments. However, recordings performed outside laboratory settings are required to test the ecologi…
View article: Human-Induced Pluripotent Stem Cell Technology: Toward the Future of Personalized Psychiatry
Human-Induced Pluripotent Stem Cell Technology: Toward the Future of Personalized Psychiatry Open
The polygenic and multifactorial nature of many psychiatric disorders has hampered implementation of the personalized medicine approach in clinical practice. However, induced pluripotent stem cell (iPSC) technology has emerged as an innova…
View article: World Federation of Societies of Biological Psychiatry (WFSBP) guidelines for treatment of anxiety, obsessive-compulsive and posttraumatic stress disorders – Version 3. Part I: Anxiety disorders
World Federation of Societies of Biological Psychiatry (WFSBP) guidelines for treatment of anxiety, obsessive-compulsive and posttraumatic stress disorders – Version 3. Part I: Anxiety disorders Open
It is the goal of this initiative to provide treatment guidance for these disorders that has validity throughout the world.