Giuseppe Rainaldi
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View article: Discovering the miR-26a-5p Targetome in Prostate Cancer Cells
Discovering the miR-26a-5p Targetome in Prostate Cancer Cells Open
Purpose. miR-26a-5p is a tumor suppressor (TS) miRNA often downregulated in several tumor tissues and tumor cell lines. In this work, we performed the re-expression of the miR-26a-5p in DU-145 prostate cancer cells to collect genes interac…
View article: The miRNA Pull Out Assay as a Method to Validate the miR-28-5p Targets Identified in Other Tumor Contexts in Prostate Cancer
The miRNA Pull Out Assay as a Method to Validate the miR-28-5p Targets Identified in Other Tumor Contexts in Prostate Cancer Open
miR-28-5p is an intragenic miRNA which is underexpressed in several tumor types showing a tumor suppressor (TS) activity. Routinely, the known miR-28-5p targets are validated in specific tumor contexts but it is unclear whether these targe…
View article: Discovering miRNA Regulatory Networks in Holt–Oram Syndrome Using a Zebrafish Model
Discovering miRNA Regulatory Networks in Holt–Oram Syndrome Using a Zebrafish Model Open
MicroRNAs (miRNAs) are small non-coding RNAs that play an important role in the post-transcriptional regulation of gene expression. miRNAs are involved in the regulation of many biological processes such as differentiation, apoptosis, and …