G. Scheuch
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View article: Aerosole: das ignorierte Problem
Aerosole: das ignorierte Problem Open
One central topic has been criminally neglected in the analysis of the corona pandemic: the role of aerosols in the transmission of viruses. Aerosol medicine had already established before 1990 that even when breathing calmly, tiny aerosol…
View article: Exhaled aerosols among PCR-confirmed SARS-CoV-2-infected children
Exhaled aerosols among PCR-confirmed SARS-CoV-2-infected children Open
Background Available data on aerosol emissions among children and adolescents during spontaneous breathing are limited. Our aim was to gain insight into the role of children in the spread of severe acute respiratory syndrome coronavirus 2 …
View article: Aerosol measurement identifies SARS-CoV 2 PCR positive adults compared with healthy controls
Aerosol measurement identifies SARS-CoV 2 PCR positive adults compared with healthy controls Open
Background SARS-CoV-2 is spread primarily through droplets and aerosols. Exhaled aerosols are generated in the lung periphery by ‘reopening of collapsed airways’. Aerosol measuring may detect highly contagious individuals (“super spreaders…
View article: COVID-19 symptoms reduce with targeted hydration of the nose, larynx and trachea
COVID-19 symptoms reduce with targeted hydration of the nose, larynx and trachea Open
Dirty air and poor access to healthcare threatens the lives of billions of people in low-income regions of the world. We investigated whether upper-airway hydration might alter two-phase flow in the airways on normal tidal breathing and be…
View article: Use of Portable Air Purification Systems to Eliminate Aerosol Particles from Patient Rooms
Use of Portable Air Purification Systems to Eliminate Aerosol Particles from Patient Rooms Open
SARS-CoV-2 is mainly transmitted via airborne aerosols. We determined the efficacy of two different indoor air-purification systems and compared them to conventional measures of room ventilation. Radioactive particles with a mass median ae…
View article: COVID-19 symptoms reduce with targeted hydration of the nose, larynx and trachea
COVID-19 symptoms reduce with targeted hydration of the nose, larynx and trachea Open
Dirty air and poor access to healthcare threatens the lives of billions of people in low-income regions of the world. We investigated whether upper-airway hydration might alter two-phase flow in the airways on normal tidal breathing and be…
View article: Breathing Is Enough: For the Spread of Influenza Virus and SARS-CoV-2 by Breathing Only
Breathing Is Enough: For the Spread of Influenza Virus and SARS-CoV-2 by Breathing Only Open
Background: The transmission of respiratory viruses such as influenza and corona viruses from one person to another is still not fully understood. Methods: A literature search showed that there is a strong scientific rationale and evidence…
View article: Targeting intracellular signaling as an antiviral strategy: aerosolized LASAG for the treatment of influenza in hospitalized patients
Targeting intracellular signaling as an antiviral strategy: aerosolized LASAG for the treatment of influenza in hospitalized patients Open
Influenza has been a long-running health problem and novel antiviral drugs are urgently needed. In pre-clinical studies, we demonstrated broad antiviral activity of D, L-lysine-acetylsalicylate glycine (LASAG) against influenza virus (IV) …
View article: Targeting intracellular signaling as an antiviral strategy: aerosolized LASAG for the treatment of influenza in hospitalized patients
Targeting intracellular signaling as an antiviral strategy: aerosolized LASAG for the treatment of influenza in hospitalized patients Open
Influenza has been a long-running health problem and novel antiviral drugs are urgently needed. In pre-clinical studies, we demonstrated broad antiviral activity of D, L-lysine-acetylsalicylate glycine (LASAG) against influenza virus (IV) …
View article: Pharmacodynamics, Pharmacokinetics, and Antiviral Activity of BAY 81-8781, a Novel NF-κB Inhibiting Anti-influenza Drug
Pharmacodynamics, Pharmacokinetics, and Antiviral Activity of BAY 81-8781, a Novel NF-κB Inhibiting Anti-influenza Drug Open
Influenza is a respiratory disease that causes annual epidemics. Antiviral treatment options targeting the virus exist, but their efficiency is limited and influenza virus strains easily develop resistance. Thus, new treatment strategies a…