Giacomo Zanelli
YOU?
Author Swipe
View article: Discordant Liver Fibrosis Predictors in Virologically Suppressed People Living with HIV without Hepatitis Virus Infection
Discordant Liver Fibrosis Predictors in Virologically Suppressed People Living with HIV without Hepatitis Virus Infection Open
Severe liver fibrosis (LF) is associated with poor long-term liver-related outcomes in people living with HIV (PLWH). The study aimed to explore the prevalence and predictors of LF and the concordance between different non-invasive methods…
View article: Association of Toll-like receptor 7 variants with life-threatening COVID-19 disease in males: findings from a nested case-control study
Association of Toll-like receptor 7 variants with life-threatening COVID-19 disease in males: findings from a nested case-control study Open
Background: Recently, loss-of-function variants in TLR7 were identified in two families in which COVID-19 segregates like an X-linked recessive disorder environmentally conditioned by SARS-CoV-2. We investigated whether the two families re…
View article: Author response: Association of Toll-like receptor 7 variants with life-threatening COVID-19 disease in males: findings from a nested case-control study
Author response: Association of Toll-like receptor 7 variants with life-threatening COVID-19 disease in males: findings from a nested case-control study Open
Background: Recently, loss-of-function variants in TLR7 were identified in two families in which COVID-19 segregates like an X-linked recessive disorder environmentally conditioned by SARS-CoV-2.We investigated whether the two families rep…
View article: An intraoperative study with <i>ex vivo</i> fluorescence confocal microscopy: diagnostic accuracy of the three visualization modalities
An intraoperative study with <i>ex vivo</i> fluorescence confocal microscopy: diagnostic accuracy of the three visualization modalities Open
Ex-vivo fluorescence confocal microscopy (FCM) is an imaging technique that captures real time digital images of freshly excised tissue with quasi histopathological resolution. FCM reduces time to image acquisition compared to hematoxylin …
View article: Predicting 2-drug antiretroviral regimen efficacy by genotypic susceptibility score: results from a cohort study
Predicting 2-drug antiretroviral regimen efficacy by genotypic susceptibility score: results from a cohort study Open
Background: HIV drug resistance has a deleterious effect on the virological outcome of antiretroviral therapy (ART). The aim of the study was to evaluate the ability of genotypic susceptibility score (GSS) to predict virological outcome fo…
View article: Impact of transmitted HIV-1 drug resistance on the efficacy of first-line antiretroviral therapy with two nucleos(t)ide reverse transcriptase inhibitors plus an integrase inhibitor or a protease inhibitor
Impact of transmitted HIV-1 drug resistance on the efficacy of first-line antiretroviral therapy with two nucleos(t)ide reverse transcriptase inhibitors plus an integrase inhibitor or a protease inhibitor Open
Our data support the need for NRTI resistance genotyping in patients starting an INSTI-based first-line ART.
View article: "EFFICACY AND SAFETY OF 2-DRUG COMBINATION ANTIRETROVIRAL THERAPY IN CLINICAL PRACTICE: RESULTS FROM A SINGLE CENTER STUDY"
"EFFICACY AND SAFETY OF 2-DRUG COMBINATION ANTIRETROVIRAL THERAPY IN CLINICAL PRACTICE: RESULTS FROM A SINGLE CENTER STUDY" Open
N. Title:
\nEfficacy and safety of 2-drug combination antiretroviral therapy in clinical practice:
\nresults from a single center study
\nP 8
\nAuthors:
\nAffiliation:
\n1Infectious Diseases Unit, Azienda Ospedaliera Universitaria Senese, …
View article: Impact of transmitted drug resistance in naïve-patients starting 2 NRTI plus a boosted protease-inhibitor (PI) or integrase-inhibitor (INSTI).
Impact of transmitted drug resistance in naïve-patients starting 2 NRTI plus a boosted protease-inhibitor (PI) or integrase-inhibitor (INSTI). Open
Background The role of transmitted drug resistance (TDR) in predicting outcomes of initial antiretroviral therapy including PI or INSTI has not been fully explored.
\nMethods From the ARCA database we selected adult naïve HIV-1 infected p…