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View article: Discovery and antibacterial activity of glabramycin A–C from Neosartorya glabra by an antisense strategy
Discovery and antibacterial activity of glabramycin A–C from Neosartorya glabra by an antisense strategy Open
View article: The preparation of zaragozic acid A analogues by directed biosynthesis.
The preparation of zaragozic acid A analogues by directed biosynthesis. Open
Zaragozic acid A analogues are produced by an unidentified sterile fungus when it is exogenously supplied with 2-thiophenecarboxylic acid, 3-thiophenecarboxylic acid, 2-furoic acid, 2-fluorobenzoic acid, 3-fluorobenzoic acid, or 4-fluorobe…
View article: Microbial transformations of immunosuppressive compounds. IV. Hydroxylation and hemiketal formation of ascomycin(immunomycin) by Streptomyces sp. MA6970(ATCC No.55281).
Microbial transformations of immunosuppressive compounds. IV. Hydroxylation and hemiketal formation of ascomycin(immunomycin) by Streptomyces sp. MA6970(ATCC No.55281). Open
The important immunosuppressive agents FK 5061>2) and ascomycin3~5) (1) have been the target of intensive structure-activity relationship (SAR) studies6).FK 506 recently received FDAapproval for liver organ transplantation in the United St…