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Preservative-Free Gel-Formulated Glaucoma Therapies: Learning from the Past, Looking to the Future Open
Overall, PF gel-formulated agents appear to be safer than and as effective as equivalent preserved antiglaucoma medications.
Evidence in Practice: A Review of Real-Life Studies and Clinical Experience with the Preservative-Free Tafluprost (0.0015%) and Timolol (0.5%) Fixed-Dose Combination Open
The preservative-free fixed-dose combination formulation of 0.0015% tafluprost and 0.5% timolol (PF tafluprost/timolol FC) is among the topical intraocular pressure (IOP)-lowering therapies commonly used second-line for the management of o…
MERCURY-3: a randomized comparison of netarsudil/latanoprost and bimatoprost/timolol in open-angle glaucoma and ocular hypertension Open
Purpose To compare the efficacy and safety of the fixed-dose combination (FDC) of netarsudil 0.02%/latanoprost 0.005% ophthalmic solution (NET/LAT; Roclanda ® ) with bimatoprost 0.03%/timolol maleate 0.5% (BIM/TIM; Ganfort ® ) ophthalmic s…
A comparison of country-level data from the VISIONARY study examining treatment outcomes with preservative-free tafluprost/timolol fixed-dose combination therapy Open
Subanalysis of VISIONARY study data revealed significant IOP reductions following a switch to the PF tafluprost/timolol FC from either PGA or beta-blocker topical monotherapy. Cross-country variation was likely due to baseline IOP differen…
Comparison of inner macular thickness and superficial macular capillary vessel density acquired using classic and high-definition optical coherence tomography angiography scans Open
Background: In ophthalmology, thickness and vessel density (VD) measurements for the 6 x 6 mm inner macular retinal area have received increasing attention in glaucomatous progression research. For this area, the Angiovue optical coherence…
Myopic Peripapillary Pits with Spatially Corresponding Localized Visual Field Defects: A Progressive Japanese and a Cross-Sectional European Case Open
We report 2 peripapillary pit cases, in which the isolated visual field defects spatially correspond to the pit-related retinal nerve fiber layer and optical coherence tomography (OCT) angiography (OCTA) perfusion damage areas. A high myop…
Influence of painless one-eye blindness on depression, anxiety and quality of life in glaucoma patients with a normal fellow eye Open
Background For clinical practice it is important to evaluate and compare anxiety, depression and quality of life of glaucoma patients with painless one-eye blindness and a normal fellow eye to unaffected age-matched individuals from a simi…
Editorial to the OCT Angiography in Glaucoma series Open
Editorial to the OCT Angiography in Glaucoma seriesOptical coherence tomography angiography (OCT angiography) applied for glaucoma research and glaucoma patient management is one of the highest ranked and most rapidly developing area of op…
Optical coherence tomography angiography in glaucoma: analysis of the vessel density—visual field sensitivity relationship Open
Glaucoma, a well-defined group of progressive optic neuropathies is one of the leading causes of irreversible blindness worldwide. In order to stop or slow down the progression of glaucomatous vision deterioration, intraocular pressure red…
View article: Correction to: Treatment of Open-Angle Glaucoma and Ocular Hypertension with Preservative-Free Tafluprost/Timolol Fixed-Dose Combination Therapy: The VISIONARY Study
Correction to: Treatment of Open-Angle Glaucoma and Ocular Hypertension with Preservative-Free Tafluprost/Timolol Fixed-Dose Combination Therapy: The VISIONARY Study Open
In the original article, the The VISIONARY Study Group Principal Investigator Jose Javier Garcia-Medina.
Real-life experience of using brinzolamide/brimonidine fixed drop combination in a tertiary glaucoma centre Open
Purpose To investigate the intraocular pressure (IOP)-lowering efficacy and tolerance of brinzolamide/brimonidine fixed combination (BBFC) under real-life conditions in a tertiary glaucoma centre. Methods Medical records of all ocular hype…
Peripapillary non-flow area measurement for the measurement of progressive localized glaucomatous perfusion damage Open
Purpose: To investigate the applicability of peripapillary non-flow area (PNFA) measurement in the radial peripapillary capillaries (RPC) layer for the measurement of progressive localized glaucomatous perfusion damage. Methods: A research…
Circumpapillary structure-function relationships with microperimetry and spectral domain optical coherence tomography in glaucoma: a pilot study Open
In our pilot study, the circumpapillary structure-function relationship was more extensive for cpTR thickness and cpGCC thickness than for cpRNFL thickness, which suggests that the former parameters may require greater attention in structu…
A deep learning approach to automatic detection of early glaucoma from visual fields Open
The proposed CNN offers high classification performance for the discrimination of control and early-glaucoma VFs when compared with standard clinical decision measures. The CNN classification, aided by saliency visualization, may support c…
View article: Diurnal and 24-h Intraocular Pressures in Glaucoma: Monitoring Strategies and Impact on Prognosis and Treatment
Diurnal and 24-h Intraocular Pressures in Glaucoma: Monitoring Strategies and Impact on Prognosis and Treatment Open
The present review casts a critical eye on intraocular pressure (IOP) monitoring and its value in current and future glaucoma care. Crucially, IOP is not fixed, but varies considerably during the 24-h cycle and between one visit and anothe…
Optical Coherence Tomography Angiography in Glaucoma Open
Optical coherence tomography angiography (OCTA) comprises different OCT-based technologies developed for non-invasive assessment and measurement of optic nerve head and retinal perfusion. Currently the most clinically established approach …
Referral for first glaucoma surgery in Europe, the ReF-GS study Open
Purpose: To analyze the appropriateness of referrals for incisional glaucoma-surgery in Europe. Methods: Referrals for the first open-angle glaucoma surgery between January and October 2017 were analyzed in 18 countries: 8 “old” European U…
View article: Pest categorisation of Curtobacterium flaccumfaciens pv. flaccumfaciens
Pest categorisation of Curtobacterium flaccumfaciens pv. flaccumfaciens Open
Following a request from the European Commission, the EFSA Panel on Plant Health performed a pest categorisation of the seed-borne bacterium Curtobacterium flaccumfaciens pv. flaccumfaciens. The pest is regulated in Council Directive 2000/…
View article: Pest categorisation of ‘Blight and blight‐like’ diseases of citrus
Pest categorisation of ‘Blight and blight‐like’ diseases of citrus Open
The EFSA Panel on Plant Health performed a pest categorisation of 'Blight and blight-like' for the EU territory. Blight is a major disease of citrus. Similar 'blight-like' diseases are also known (e.g. declinio, declinamiento) and are addr…
View article: Pest categorisation of Citrus leprosis viruses
Pest categorisation of Citrus leprosis viruses Open
The EFSA Panel on Plant Health performed a pest categorisation of the Citrus leprosis viruses for the EU territory and identified five distinct viruses, Citrus leprosis virus C (CiLV-C), Citrus leprosis virus C2 (CiLV-C2), Hibiscus green s…
View article: Pest categorisation of naturally‐spreading psorosis
Pest categorisation of naturally‐spreading psorosis Open
The EFSA Panel on Plant Health performed a pest categorisation of naturally-spreading psorosis of citrus for the European Union. Naturally-spreading psorosis is poorly defined, because the status of both the disease and its causal agent(s)…
Detection of central visual field defects in early glaucomatous eyes: Comparison of Humphrey and Octopus perimetry Open
Both HFA 10-2 and Octopus G1programs showed CVFD not present at HFA 24-2 test although the agreement was moderate. The use of a single Octopus G1 examination may represent a practical compromise for the assessment of both central and perip…
View article: Pest categorisation of Beet curly top virus (non‐EU isolates)
Pest categorisation of Beet curly top virus (non‐EU isolates) Open
The EFSA Panel on Plant Health performed a pest categorisation of non-EU isolates of Beet curly topvirus (BCTV) for the European Union territory. The virus causes severe diseases in beet, tomatoes andpepper crops, occurs predominantly in w…
View article: Pest categorisation of Satsuma dwarf virus
Pest categorisation of Satsuma dwarf virus Open
The EFSA Panel on Plant Health performed a pest categorisation of Satsuma dwarf virus (SDV) for the EU territory. SDV is a well-known pathogen and the type species of the genus Sadwavirus in the family Secoviridae. SDV is now considered to…