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View article: Lymphocyte damage in four differently treated prostate radiotherapy cohort
Lymphocyte damage in four differently treated prostate radiotherapy cohort Open
Background: As the assessment of lymphocyte damage caused by radiotherapy gains importance as immunotherapies are used more frequently. Furthermore, there is scarce data to compare the biological dose of radiotherapy techniques in the same…
View article: The multimodal brain tumor image segmentation benchmark (brats)
The multimodal brain tumor image segmentation benchmark (brats) Open
In this paper we report the set-up and results of the Multimodal Brain Tumor Image Segmentation Benchmark (BRATS) organized in conjunction with the MICCAI 2012 and 2013 conferences. Twenty state-of-the-art tumor segmentation algorithms wer…
View article: Neck Node Squamous Cell Metastasis from Unknown Primary and Mutagen Sensitivity: A Case Series
Neck Node Squamous Cell Metastasis from Unknown Primary and Mutagen Sensitivity: A Case Series Open
Most of the neck node metastases from cancer of unknown primary (CUP) are squamous cell carcinomas (SCCs). The majority of which are human papillomavirus (HPV)-related, frequently show cystic morphology referring to Waldeyer’s ring origin.…
View article: Cover Image, Volume 46, Issue 8
Cover Image, Volume 46, Issue 8 Open
The cover image is based on the Research Article A data-driven optimal control method for endoplasmic reticulum membrane compartmentalization in budding yeast cells by Aymen Laadhari et al., https://doi.org/10.1002/mma.9021.
View article: A data-driven model for endoplasmic reticulum membrane compartmentalization in budding yeast cells
A data-driven model for endoplasmic reticulum membrane compartmentalization in budding yeast cells Open
We present a framework to model and provide numerical evidence for compartmentalization in the yeast endoplasmic reticulum. Measurement data is collected and an optimal control problem is formulated as a regularized inverse problem. To our…
View article: Prostate Cancer Survivors Present Long-Term, Residual Systemic Immune Alterations
Prostate Cancer Survivors Present Long-Term, Residual Systemic Immune Alterations Open
Background: The development of cancer and anti-tumor therapies can lead to systemic immune alterations but little is known about how long immune dysfunction persists in cancer survivors. Methods: We followed changes in the cellular immune …
View article: Chromosomal Aberrations in Blood Lymphocytes as Predictors of Respiratory Function After Stereotactic Lung Irradiation
Chromosomal Aberrations in Blood Lymphocytes as Predictors of Respiratory Function After Stereotactic Lung Irradiation Open
Due to the profound difference in radiosensitivity of patients and various side effects caused by this phenomenon, a radiosensitivity marker is needed. Prediction by a marker may help personalise the treatment. In this study, we tested chr…
View article: Az apai vonalú N haplocsoport szerepe a mai baskírok, tatárok és magyarok genetikai kapcsolatrendszerében
Az apai vonalú N haplocsoport szerepe a mai baskírok, tatárok és magyarok genetikai kapcsolatrendszerében Open
A specific genetic relationship under paternal haplogroup N among Hungarians, Bashkirs and Tatars is presented. The study identified two, approximately 2700–2800 years old paternal ancestor under subhapolgroup N-B539, whose descendants hav…
View article: Quantifying biological effects of radiation from high-energy linear accelerators on lymphocytes
Quantifying biological effects of radiation from high-energy linear accelerators on lymphocytes Open
The aim of this study was to investigate the radiobiological effects of flattening filter (FF) and flattening filter-free (FFF) modes of linear electron accelerators and to understand whether there is any difference between the effects of …
View article: III. Béla király csontjainak tanúsága – Az Árpád-ház eredete
III. Béla király csontjainak tanúsága – Az Árpád-ház eredete Open
The role of applications based on machine learning is continuously growing in the industry, health sector/bioinformatics and scientific research. American researchers published a bit more than 10 years ago the first machine learning algori…
View article: Progressive breast fibrosis caused by extreme radiosensitivity: Oncocytogenetic diagnosis and treatment by reconstructive flap surgery
Progressive breast fibrosis caused by extreme radiosensitivity: Oncocytogenetic diagnosis and treatment by reconstructive flap surgery Open
Background Fibrosis, a proliferative response of fibrocytes after tissue injury, is a common sequela of external radiotherapy and can vary greatly among patients even in the absence of DNA repair syndromes, due to their different intrinsic…
View article: A Bayesian Framework for the Analog Reconstruction of Kymographs From Fluorescence Microscopy Data
A Bayesian Framework for the Analog Reconstruction of Kymographs From Fluorescence Microscopy Data Open
Kymographs are widely used to represent and analyse spatio-temporal dynamics of fluorescence markers along curvilinear biological compartments. These objects have a singular geometry, thus kymograph reconstruction is inherently an analog i…
View article: Restoration of the Patient-Specific Anatomy of the Proximal and Distal Parts of the Humerus
Restoration of the Patient-Specific Anatomy of the Proximal and Distal Parts of the Humerus Open
Background: In computer-assisted reconstructive surgeries, the contralateral anatomy is established as the best available reconstruction template. However, existing intra-individual bilateral differences or a pathological, contralateral hu…
View article: A Novel Registration-Based Approach for 3D Assessment of Posttraumatic Distal Humeral Deformities
A Novel Registration-Based Approach for 3D Assessment of Posttraumatic Distal Humeral Deformities Open
Background: With current 3-dimensional (3D) computer-based methods for the assessment of deformities, a surface registration method is applied to superimpose a computer model of the pathological bone onto a mirrored computer model of the c…
View article: Warning About The Risk Of Blood Flow Stagnation After Transcatheter Aortic Valve Implantation
Warning About The Risk Of Blood Flow Stagnation After Transcatheter Aortic Valve Implantation Open
In this work, the hemodynamics in the sinuses of Valsalva after Transcatheter Aortic Valve Implantation is numerically examined. We focus on the physical results in the two-dimensional case. We use a finite element methodology based on a L…
View article: Isotropic Total Variation Regularization of Displacements in Parametric Image Registration
Isotropic Total Variation Regularization of Displacements in Parametric Image Registration Open
Spatial regularization is essential in image registration, which is an ill-posed problem. Regularization can help to avoid both physically implausible displacement fields and local minima during optimization. Tikhonov regularization (squar…
View article: Feasibility of Diffusion Tractography for the Reconstruction of Intra-Thalamic and Cerebello-Thalamic Targets for Functional Neurosurgery: A Multi-Vendor Pilot Study in Four Subjects
Feasibility of Diffusion Tractography for the Reconstruction of Intra-Thalamic and Cerebello-Thalamic Targets for Functional Neurosurgery: A Multi-Vendor Pilot Study in Four Subjects Open
Functional stereotactic neurosurgery by means of deep brain stimulation or ablation provides an effective treatment for movement disorders, but the outcome of surgical interventions depends on the accuracy by which the target structures ar…
View article: Implicit Eulerian Fluid-Structure Interaction Method for the Modeling of Highly Deformable Elastic Membranes
Implicit Eulerian Fluid-Structure Interaction Method for the Modeling of Highly Deformable Elastic Membranes Open
ISSN:1307-6892