Gabriel Théberge-Julien
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View article: Unraveling Lyophilization and Redispersion Effects on Miktoarm Polymer-Based Nanoformulations
Unraveling Lyophilization and Redispersion Effects on Miktoarm Polymer-Based Nanoformulations Open
To enhance the scope of therapeutic interventions using star polymeric nanoparticles of desired concentrations, an understanding of the effect of converting aqueous formulations into stable redispersible dry powders by freeze drying on the…
View article: Manganese homeostasis modulates glucan and chitin unmasking in the opportunistic yeast <i>Candida albicans</i>
Manganese homeostasis modulates glucan and chitin unmasking in the opportunistic yeast <i>Candida albicans</i> Open
Candida albicans is a commensal fungus and also the most prevalent human fungal pathogen. The ability of this opportunistic yeast to acquire and maintain homeostatic levels of manganese (Mn), particularly in the metal-limited host environm…
View article: Manganese homeostasis modulates glucan and chitin unmasking in the opportunistic yeast <i>Candida albicans</i>
Manganese homeostasis modulates glucan and chitin unmasking in the opportunistic yeast <i>Candida albicans</i> Open
Candida albicans is a commensal fungus and also the most prevalent human fungal pathogen. The ability of this opportunistic yeast to acquire and maintain homeostatic levels of manganese (Mn), particularly in the metal-limited host environm…
View article: Multifaceted ligand design facilitates chemical- or peptide-mediated linking of hollow gold nanoshells with tuned interparticle distance, interference and cytotoxicities
Multifaceted ligand design facilitates chemical- or peptide-mediated linking of hollow gold nanoshells with tuned interparticle distance, interference and cytotoxicities Open
Rational design of tunable multi-tasking ligands offers a versatile platform to link hollow gold nanoshells, in which molecular weight of polyethylene glycol arms and length of the spacer play key roles in composition control and optical p…
View article: Colchicine reduces lung injury in experimental acute respiratory distress syndrome
Colchicine reduces lung injury in experimental acute respiratory distress syndrome Open
The acute respiratory distress syndrome (ARDS) is characterized by intense dysregulated inflammation leading to acute lung injury (ALI) and respiratory failure. There are no effective pharmacologic therapies for ARDS. Colchicine is a low-c…
View article: Expression, subcellular localization, and phosphorylation of MK5 in adult cardiac ventricular fibroblasts
Expression, subcellular localization, and phosphorylation of MK5 in adult cardiac ventricular fibroblasts Open
MAP kinase-activated protein kinase-5 (MK5) plays an important role in cardiac fibroblast function. Although p38 MAPK and atypical MAPKs and ERK3 and ERK4 have been identified as activators of MK5, the kinases that activate MK5 remain cont…
View article: Colchicine Reduces Lung Injury in Experimental Acute Respiratory Distress Syndrome
Colchicine Reduces Lung Injury in Experimental Acute Respiratory Distress Syndrome Open
The acute respiratory distress syndrome (ARDS) is characterized by intense dysregulated inflammation leading to lung injury and respiratory failure. We studied the effects of colchicine pre-treatment on oleic acid-induced ARDS in rats. Col…
View article: Beneficial Effects of Reconstituted High-Density Lipoprotein (rHDL) on Circulating CD34+ Cells in Patients after an Acute Coronary Syndrome
Beneficial Effects of Reconstituted High-Density Lipoprotein (rHDL) on Circulating CD34+ Cells in Patients after an Acute Coronary Syndrome Open
The relative increase in circulating CD34+ cells and the low SDF-1 levels observed following rHDL infusions in ACS patients point towards a role of rHDL in cardiovascular repair mechanisms.