Gabriela Negroiu
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View article: Ultra-High Dose Rate Ionizing Radiation for FLASH Radiotherapy Applications
Ultra-High Dose Rate Ionizing Radiation for FLASH Radiotherapy Applications Open
Radiation therapy (RT) is an essential component of curative cancer treatment. Technological advances in RT aim to make treatments more precise, efficient, and personalized. Recent FLASH-induced radiotherapeutic strategies employ ultra-hig…
View article: Interleukin-8 in Melanoma Pathogenesis, Prognosis and Therapy—An Integrated View into Other Neoplasms and Chemokine Networks
Interleukin-8 in Melanoma Pathogenesis, Prognosis and Therapy—An Integrated View into Other Neoplasms and Chemokine Networks Open
Cutaneous melanoma accounts for only about 7% of skin cancers but is causing almost 90% of deaths. Melanoma cells have a distinct repertoire of mutations from other cancers, a high plasticity and degree of mimicry toward vascular phenotype…
View article: Innovative Hybrid Materials with Improved Tensile Strength Obtained by 3D Printing
Innovative Hybrid Materials with Improved Tensile Strength Obtained by 3D Printing Open
Barium titanate (BT) and barium strontium titanate (BST) are one of the most studied ferroelectric materials with excellent piezoelectric properties, which can be used to stimulate bone formation by applying an electrical field. It is know…
View article: Interaction Analysis of Commercial Graphene Oxide Nanoparticles with Unicellular Systems and Biomolecules
Interaction Analysis of Commercial Graphene Oxide Nanoparticles with Unicellular Systems and Biomolecules Open
The ability of commercial monolayer graphene oxide (GO) and graphene oxide nanocolloids (GOC) to interact with different unicellular systems and biomolecules was studied by analyzing the response of human alveolar carcinoma epithelial cell…
View article: The Multiple Roles of Tyrosinase-Related Protein-2/L- Dopachrome Tautomerase in Melanoma: Biomarker, Therapeutic Target, and Molecular Driver in Tumor Progression
The Multiple Roles of Tyrosinase-Related Protein-2/L- Dopachrome Tautomerase in Melanoma: Biomarker, Therapeutic Target, and Molecular Driver in Tumor Progression Open
Cutaneous malignant melanoma (CMM), which is ranked as the 8th most common cancers in the US, makes 4–7% of skin cancers but it causes approximately 80% of skin cancer deaths. CMM is characterized by insidious and fast progression, heterog…
View article: Variations in the expression of TIMP1, TIMP2 and TIMP3 in cutaneous melanoma with regression and their possible function as prognostic predictors
Variations in the expression of TIMP1, TIMP2 and TIMP3 in cutaneous melanoma with regression and their possible function as prognostic predictors Open
Regression in melanoma is a frequent biological event of uncertain prognostic value as the lesion exhibits heterogeneous phenotypical features, both at the morphological and immunohistochemical level. In the present study, we examined the …