Gabriele Calaminus
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View article: Two Decades of Outcomes and Quality of Life Following Pencil Beam Scanning Proton Therapy in Children and Adolescents with Rhabdomyosarcoma
Two Decades of Outcomes and Quality of Life Following Pencil Beam Scanning Proton Therapy in Children and Adolescents with Rhabdomyosarcoma Open
Background: RMS is the most common soft tissue sarcoma in children. Pencil beam scanning proton therapy (PBS PT) enables highly conformal dose delivery with reduced exposure to surrounding healthy structures, making it particularly suited …
View article: Finanzierung der Langzeitnachsorge nach Krebs im Kindes‑, Jugend- und jungen Erwachsenenalter
Finanzierung der Langzeitnachsorge nach Krebs im Kindes‑, Jugend- und jungen Erwachsenenalter Open
Zusammenfassung Hintergrund Nach einer Krebserkrankung haben Betroffene ein erhöhtes Risiko für somatische und psychosoziale Spätfolgen, die sich teils erst Jahrzehnte nach Therapieende manifestieren. Leitlinien empfehlen eine risikoadapti…
View article: Long‐Term Clinical Outcome and Quality of Life of Children, Adolescents, and Young Adults With Chordoma or Chondrosarcoma Treated With Pencil Beam Scanning Proton Therapy
Long‐Term Clinical Outcome and Quality of Life of Children, Adolescents, and Young Adults With Chordoma or Chondrosarcoma Treated With Pencil Beam Scanning Proton Therapy Open
Background and Aims To assess clinical outcomes and quality of life (QoL) of children, adolescents, and young adults (C‐AYAs) with chordomas (CH) or chondrosarcomas (CS) after pencil beam scanning proton therapy (pbsPT). Methods A total of…
View article: Temozolomide-based radio-chemotherapy for newly diagnosed pediatric high-grade gliomas (HIT-HGG-2007): A prospective, multicenter, single-arm, phase II trial
Temozolomide-based radio-chemotherapy for newly diagnosed pediatric high-grade gliomas (HIT-HGG-2007): A prospective, multicenter, single-arm, phase II trial Open
Background: The HIT-HGG-2007 trial investigated temozolomide (TMZ) radio-chemotherapy for pediatric patients with high-grade gliomas (pHGG) to demonstrate therapeutic non-inferiority compared to previous intensive radio-chemotherapy regime…
View article: Approaches to Invasive Fungal Diseases in Paediatric Cancer Centres: An Analysis of Current Practices and Challenges in Germany, Austria and Switzerland
Approaches to Invasive Fungal Diseases in Paediatric Cancer Centres: An Analysis of Current Practices and Challenges in Germany, Austria and Switzerland Open
Background Invasive fungal diseases (IFD) pose significant challenges in paediatric oncology. Their management is complicated by limited paediatric‐specific evidence, lack of standardised protocols and variability in resources across centr…
View article: Evaluation and implementation of multidisciplinary, standardized, guideline-based long-term follow-up care for adult survivors of childhood cancer in Germany: protocol of a prospective, multi-center, nationwide study (LE-Na)
Evaluation and implementation of multidisciplinary, standardized, guideline-based long-term follow-up care for adult survivors of childhood cancer in Germany: protocol of a prospective, multi-center, nationwide study (LE-Na) Open
Background Late effects can occur years to decades after cancer therapy, resulting in morbidity and reduced health-related quality of life. Clinical long-term follow-up (LTFU) enables timely diagnosis and treatment of these sequelae. So fa…
View article: Testicular and ovarian Juvenile granulosa cell tumors in children and adolescents: Analysis of 113 patients registered to the German Registry for Rare Pediatric Tumors (STEP)
Testicular and ovarian Juvenile granulosa cell tumors in children and adolescents: Analysis of 113 patients registered to the German Registry for Rare Pediatric Tumors (STEP) Open
Background In juvenile granulosa cell tumors (juvGCTs), impaired survival was reported after preoperative tumor rupture, peritoneal metastases, or high mitotic rate (≥20 mitoses per 10 high‐power fields). Therefore, a risk stratification w…
View article: Long‐Term Outcomes and Quality of Life of Children With Intracranial Ependymoma Treated With Pencil Beam Scanning Proton Therapy
Long‐Term Outcomes and Quality of Life of Children With Intracranial Ependymoma Treated With Pencil Beam Scanning Proton Therapy Open
Background Ependymoma is a common brain tumor in children and adolescents. Adjuvant radiation therapy improves prognosis but carries potential toxicity risks, particularly for young patients. Proton therapy (PT) offers better conformal tre…
View article: Organizing long-term follow-up care for pediatric cancer survivors: a socio-ecological approach
Organizing long-term follow-up care for pediatric cancer survivors: a socio-ecological approach Open
This study examines the organization of long-term follow-up care for pediatric cancer survivors through the lens of Bronfenbrenners’ Ecological Systems Theory (EST). Using focus group discussions with survivors and healthcare professionals…
View article: “You First Have to Check Out the Doctors”: Transition Expectations and Experiences of Survivors After Pediatric Cancer
“You First Have to Check Out the Doctors”: Transition Expectations and Experiences of Survivors After Pediatric Cancer Open
Purpose The shift from child‐centered to adult‐focused healthcare presents social and psychological challenges for adolescents and young adults with chronic conditions, which can affect their participation in follow‐up care. This study aim…
View article: Effectiveness of structured, multidisciplinary long-term care for pediatric cancer survivors: protocol of the multicenter, randomized-controlled AELKI study
Effectiveness of structured, multidisciplinary long-term care for pediatric cancer survivors: protocol of the multicenter, randomized-controlled AELKI study Open
View article: Acute toxicity of chemotherapy in central nervous system germ cell tumour patients according to age
Acute toxicity of chemotherapy in central nervous system germ cell tumour patients according to age Open
Background SIOP-CNS-GCT-II European trial was opened for the treatment of patients of any age with central nervous system germ cell tumour (CNS-GCT). Four courses of pre-irradiation chemotherapy were delivered. The influence of patient age…
View article: GCT-08. THE PURSUIT OF OPTIMUM TREATMENT FOR NONGERMINOMATOUS GERM CELL TUMOURS (NGGCT) OF THE CNS – A PROGRESS REPORT FROM THE EUROPEAN GROUP (SIOP CNS GCT II)
GCT-08. THE PURSUIT OF OPTIMUM TREATMENT FOR NONGERMINOMATOUS GERM CELL TUMOURS (NGGCT) OF THE CNS – A PROGRESS REPORT FROM THE EUROPEAN GROUP (SIOP CNS GCT II) Open
BACKGROUND Controversy surrounds the optimum treatment for localised nongerminomatous germ-cell-tumours (NGGCT). The European group has employed more dose-intense chemotherapy followed by 54 Gy focal radiotherapy (fRT), whilst others addit…
View article: GCT-19. SIOP CNS GCT II: PRESENTATION AND OUTCOME OF BIFOCAL NON-GERMINOMATOUS GERM CELL TUMOURS (NGGCTS)
GCT-19. SIOP CNS GCT II: PRESENTATION AND OUTCOME OF BIFOCAL NON-GERMINOMATOUS GERM CELL TUMOURS (NGGCTS) Open
BACKGROUND Between 2/2012 and 7/2018, 112 patients with non-germinoma were registered as intend-to-treat patients within the SIOP CNS GCT II trial: 88 patients were male and 24 female. Median age was 13 years (range: 0,1-25,1 years). 95 pa…
View article: GCT-20. PRESENTATION AND OUTCOME OF BIFOCAL GERMINOMA TREATED ACCORDING TO SIOP CNS GCT II
GCT-20. PRESENTATION AND OUTCOME OF BIFOCAL GERMINOMA TREATED ACCORDING TO SIOP CNS GCT II Open
BACKGROUND Between 2/2012 and 7/2018, 261 patients with germinoma were registered as intent-to-treat patients within the SIOP CNS GCT II trial. 209 patients were male/ 52 female. The median age was 14.1 years (range 5,0-41,0 years). 194 pa…
View article: Imaging in malignant germ cell tumors involving the hypothalamo-neurohypophyseal axis: the evaluation of the posterior pituitary bright spot is essential
Imaging in malignant germ cell tumors involving the hypothalamo-neurohypophyseal axis: the evaluation of the posterior pituitary bright spot is essential Open
View article: Non-Syndromic and Syndromic Defects in Children with Extracranial Germ Cell Tumors: Data of 2610 Children Registered with the German MAKEI 96/MAHO 98 Registry Compared to the General Population
Non-Syndromic and Syndromic Defects in Children with Extracranial Germ Cell Tumors: Data of 2610 Children Registered with the German MAKEI 96/MAHO 98 Registry Compared to the General Population Open
GCTs are developmental tumors and are likely to reflect ontogenetic and teratogenetic determinants. The objective of this study was to identify syndromes with or without congenital anomalies and non-syndromic defects as potential risk fact…
View article: Author Correction: A joint international consensus statement for measuring quality of survival for patients with childhood cancer
Author Correction: A joint international consensus statement for measuring quality of survival for patients with childhood cancer Open
View article: Non-syndromic and Syndromic Defects in Children with Extracranial Germ Cell Tumors (eGCT): Data of 2,610 Children Registered with the German MAKEI 96/MAHO 98 Registry Compared to the General Population
Non-syndromic and Syndromic Defects in Children with Extracranial Germ Cell Tumors (eGCT): Data of 2,610 Children Registered with the German MAKEI 96/MAHO 98 Registry Compared to the General Population Open
GCTs are developmental tumors and likely to reflect ontogenetic and teratogenetic determinants. The objective was to identify syndromes with or without congenital anomalies and non-syndromic defects as potential risk factors. Patients with…
View article: A Multimodal Lifestyle Psychosocial Survivorship Program in Young Cancer Survivors
A Multimodal Lifestyle Psychosocial Survivorship Program in Young Cancer Survivors Open
Importance There is a lack of trials examining the effect of counseling interventions for child, adolescent, and younger adult (CAYA) cancer survivors. Objective To assess lifestyle habits and the psychosocial situation of CAYAs to determi…
View article: VersKiK qualitative study design: actual follow-up needs of paediatric cancer survivors, their informal caregivers and follow-up stakeholder perceptions in Germany
VersKiK qualitative study design: actual follow-up needs of paediatric cancer survivors, their informal caregivers and follow-up stakeholder perceptions in Germany Open
Introduction This article presents the study design of the qualitative part of the VersKiK study (Long-term care, care needs and wellbeing of individuals after cancer in childhood or adolescence: study protocol of a large scale multi-metho…
View article: Implementation of the Short-Form 36 (SF-36) in childhood cancer survivors: An analysis on measurement properties across 5 European countries
Implementation of the Short-Form 36 (SF-36) in childhood cancer survivors: An analysis on measurement properties across 5 European countries Open
Purpose The Short Form-36 (SF-36) is widely used in many research contexts and cultures to assess health-related quality of life (HRQOL). We investigated the measurement properties of the SF-36 in a large cohort study among childhood cance…
View article: Combination of nivolumab with standard induction chemotherapy in children and adults with EBV-positive nasopharyngeal carcinoma
Combination of nivolumab with standard induction chemotherapy in children and adults with EBV-positive nasopharyngeal carcinoma Open
Background Treatment of Epstein-Barr virus(EBV)-positive nasopharyngeal carcinoma (NPC) with cisplatin/5-fluorouracil (5-FU) induction chemotherapy, followed by radiochemotherapy and subsequent interferon‑β, has yielded high survival rates…
View article: Author Correction: A joint international consensus statement for measuring quality of survival for patients with childhood cancer
Author Correction: A joint international consensus statement for measuring quality of survival for patients with childhood cancer Open
View article: Author Correction: A joint international consensus statement for measuring quality of survival for patients with childhood cancer
Author Correction: A joint international consensus statement for measuring quality of survival for patients with childhood cancer Open
View article: Vision-related quality of life in patients with childhood-onset craniopharyngioma
Vision-related quality of life in patients with childhood-onset craniopharyngioma Open
View article: Outcome after proton beam therapy versus photon-based radiation therapy in childhood-onset craniopharyngioma patients—results of KRANIOPHARYNGEOM 2007
Outcome after proton beam therapy versus photon-based radiation therapy in childhood-onset craniopharyngioma patients—results of KRANIOPHARYNGEOM 2007 Open
Background Proton beam therapy (PBT) is being increas16ingly used to treat residual craniopharyngioma (CP) after hypothalamus-sparing surgery. Compared to photon-based radiation therapy (XRT) with PBT, less irradiation in the penumbra redu…
View article: Pencil Beam Scanning Proton Therapy for Adolescents and Young Adults with Head and Neck Sarcomas
Pencil Beam Scanning Proton Therapy for Adolescents and Young Adults with Head and Neck Sarcomas Open
View article: THU216 The Influence Of Age At Diagnosis On Clinical Presentation And Prognosis Of Childhood-onset Craniopharyngioma
THU216 The Influence Of Age At Diagnosis On Clinical Presentation And Prognosis Of Childhood-onset Craniopharyngioma Open
Disclosure: J. Beckhaus: None. C. Friedrich: None. S. Boekhoff: None. G. Calaminus: None. B. Bison: None. M. Eveslage: None. B. Timmermann: None. J. Flitsch: None. H.L. Muller: None. The association between age at diagnosis (AaD) and clini…
View article: Long Term Clinical Outcome and Quality of Life of Children, Adolescents and Young Adults Treated with Pencil Beam Scanning Proton Therapy for Rhabdomyosarcoma
Long Term Clinical Outcome and Quality of Life of Children, Adolescents and Young Adults Treated with Pencil Beam Scanning Proton Therapy for Rhabdomyosarcoma Open