Gabriele Masi
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View article: Efficacy, effectiveness, and safety/tolerability of lithium in children and adolescents up to 18 years of age with conditions other than mood disorders: A scoping review
Efficacy, effectiveness, and safety/tolerability of lithium in children and adolescents up to 18 years of age with conditions other than mood disorders: A scoping review Open
In youth, lithium is an effective medication for mood disorders, particularly for mixed and manic episodes of bipolar disorder, and is generally well-tolerated. In some clinical contexts, lithium is used off-label to manage other condition…
View article: Re-treatment with panitumumab followed by regorafenib versus the reverse sequence in chemorefractory metastatic colorectal cancer patients with RAS and BRAF wild-type circulating tumor DNA: the PARERE study by GONO
Re-treatment with panitumumab followed by regorafenib versus the reverse sequence in chemorefractory metastatic colorectal cancer patients with RAS and BRAF wild-type circulating tumor DNA: the PARERE study by GONO Open
View article: Social Media Engagement and Usage Patterns, Mental Health Comorbidities, and Empathic Measures in an Italian Adolescent Sample: A Comparative Study
Social Media Engagement and Usage Patterns, Mental Health Comorbidities, and Empathic Measures in an Italian Adolescent Sample: A Comparative Study Open
Background: The link between problematic social media (SM) use and socio-emotional deficits has limited clinical evidence. This study compares SM addiction risk and empathic abilities between psychiatric outpatients and healthy peers, expl…
View article: Risk of disease progression in first-line metastatic colorectal cancer therapy to guide disease reassessments―analysis of 11 trials by AIO and GONO
Risk of disease progression in first-line metastatic colorectal cancer therapy to guide disease reassessments―analysis of 11 trials by AIO and GONO Open
The distribution of PD events does not follow a Gaussian pattern, with the highest density observed between the third and fourth reassessment of a bimonthly surveillance schedule. In clearly unresectable patients, restaging should focus on…
View article: 375eP Biliary stenting in biliopancreatic tumors: Evidence from real-world practice
375eP Biliary stenting in biliopancreatic tumors: Evidence from real-world practice Open
View article: 163P Are clinical factors useful for identifying primary progressors (PP) in patients (pts) with hepatocellular carcinoma (HCC) undergoing first-line treatment with atezolizumab plus bevacizumab (AB)? Analysis from the Italian ARTE database
163P Are clinical factors useful for identifying primary progressors (PP) in patients (pts) with hepatocellular carcinoma (HCC) undergoing first-line treatment with atezolizumab plus bevacizumab (AB)? Analysis from the Italian ARTE database Open
View article: 329P First-line maintenance chemotherapy in patients with advanced pancreatic adenocarcinoma: A referral center monocentric cohort
329P First-line maintenance chemotherapy in patients with advanced pancreatic adenocarcinoma: A referral center monocentric cohort Open
View article: Sensory processing in autism: a call for research and action
Sensory processing in autism: a call for research and action Open
View article: Exploring autistic traits in parents of autistic children: a pilot study on the broader autism phenotype
Exploring autistic traits in parents of autistic children: a pilot study on the broader autism phenotype Open
Background Biological parents of autistic children often exhibit characteristics associated with the broader autism phenotype (BAP), a subclinical expression of autism-related traits. While BAP traits are known to be prevalent among first-…
View article: Effects of Difficulties in Executive Functions on Behavioral and Adaptive Problems in Italian Autistic Preschoolers.
Effects of Difficulties in Executive Functions on Behavioral and Adaptive Problems in Italian Autistic Preschoolers. Open
Assessment of EF in autistic preschoolers may identify those children at higher risk for emotional/behavioral problems and adaptive difficulties. EF are a crucial target for early intervention in preschoolers with autism with the potential…
View article: The Motor Melody in action Planning: The Case of Autistic Children and their Non-Autistic Siblings.
The Motor Melody in action Planning: The Case of Autistic Children and their Non-Autistic Siblings. Open
despite not being included among the diagnostic criteria, motor alterations are present in a large number of autistic individuals, detectable from an early age. Being motor signs also expressed by non-autistic siblings, our findings sugges…
View article: Chronic Tic Disorders in Youth: Clinical Phenotypes and Response to Pharmacological Treatment with Aripiprazole
Chronic Tic Disorders in Youth: Clinical Phenotypes and Response to Pharmacological Treatment with Aripiprazole Open
Background/Objectives: Tic disorders are neurodevelopmental conditions often associated with comorbidities like attention deficit hyperactivity disorder (ADHD) and autism spectrum disorder (ASD). Our aims were: (a) in a sample of youth wit…
View article: Efficacy and Safety of Lithium for Suicide and Suicide-Related Behaviors in Youth: A Review of the Literature
Efficacy and Safety of Lithium for Suicide and Suicide-Related Behaviors in Youth: A Review of the Literature Open
Objectives: This systematic review evaluates the anti-suicidal properties of Lithium in children and adolescents with Bipolar Disorder (BD), addressing gaps in evidence regarding its efficacy and safety in reducing suicidality and self-har…
View article: Extended-Release Lithium Treatment for Adolescents with Bipolar Disorder with or Without Comorbid Autism Spectrum Disorder: Protocol of a Longitudinal Prospective Naturalistic Study for the Assessment of Efficacy and Tolerability
Extended-Release Lithium Treatment for Adolescents with Bipolar Disorder with or Without Comorbid Autism Spectrum Disorder: Protocol of a Longitudinal Prospective Naturalistic Study for the Assessment of Efficacy and Tolerability Open
Background: Lithium is the gold-standard treatment for Bipolar Disorder (BD) in both adults and adolescents, effectively managing mood episodes and reducing suicide risk. While its efficacy in neurotypical youth is well established, its us…
View article: Professor Alessandro Zuddas’ Impact and Legacy: The Influential Networking and Human Connection Skills of a Passionate Scientist, Clinical Academic, and Pioneer in Child and Adolescent Psychopharmacology
Professor Alessandro Zuddas’ Impact and Legacy: The Influential Networking and Human Connection Skills of a Passionate Scientist, Clinical Academic, and Pioneer in Child and Adolescent Psychopharmacology Open
Professor Alessandro Zuddas, from the University of Cagliari (Italy), passed away prematurely in July 2022. As a prominent figure in child and adolescent neuropsychiatry, he substantially influenced the fields of neurodevelopmental disorde…
View article: Non-Suicidal Self-Injury in Eating and Feeding Disorder Patients: Characteristics and Clinical Implications in a Group of Referred Female Adolescents
Non-Suicidal Self-Injury in Eating and Feeding Disorder Patients: Characteristics and Clinical Implications in a Group of Referred Female Adolescents Open
Background: Non-suicidal self-injury (NSSI) and Feeding or Eating Disorders (FEDs) often coexist during adolescence with reciprocal influences on their clinical picture. The present study aimed to identify differences and similarities in t…
View article: Reactivity of Emotions in Adolescents - Caregivers' Tool (React): Development and Validation of a Novel Parent-Rated Measure for Assessing Emotional Dysregulation in Youth.
Reactivity of Emotions in Adolescents - Caregivers' Tool (React): Development and Validation of a Novel Parent-Rated Measure for Assessing Emotional Dysregulation in Youth. Open
This novel tool represents a valuable improvement in the assessment of ED in adolescence as it may facilitate tailored interventions to provide emotional well-being and long-term outcomes.
View article: Network meta‐analysis of adjuvant chemotherapy in biliary tract cancers: Setting the scene for new randomized evidence
Network meta‐analysis of adjuvant chemotherapy in biliary tract cancers: Setting the scene for new randomized evidence Open
Background and Aims The best adjuvant chemotherapy for resected biliary tract cancer (BTC) is under debate, with capecitabine supported by weak evidence. Aim of this network meta‐analysis is to estimate the efficacy of different phase II/I…
View article: Social Skills Interventions for Adolescents with Level 1 Autism Spectrum Disorder: A Systematic Review with Meta-Analysis of Randomized Controlled Trials.
Social Skills Interventions for Adolescents with Level 1 Autism Spectrum Disorder: A Systematic Review with Meta-Analysis of Randomized Controlled Trials. Open
At the group level, social skills training for adolescents with Level 1 ASD is efficacious, with small-to-moderate effect size. Future research should focus on personalized medicine approaches, aimed at tailoring interventions to specific …
View article: Emotional Dysregulation and Sleep Problems: A Transdiagnostic Approach in Youth
Emotional Dysregulation and Sleep Problems: A Transdiagnostic Approach in Youth Open
Background: Sleep is a complex phenomenon that affects several aspects of life, including cognitive functioning, emotional regulation, and overall well-being. Sleep disturbances, especially during adolescence, can negatively impact emotion…
View article: Deficits in emotion recognition and processing in children with high callous-unemotional traits: the role of the MAOA gene
Deficits in emotion recognition and processing in children with high callous-unemotional traits: the role of the MAOA gene Open
Children with high Callous-Unemotional (CU) traits show deficits in recognizing and processing facial expressions. Alterations in emotion recognition have been linked to a higher synaptic concentration of monoaminergic neurotransmitters. T…
View article: Internet Gaming Disorder in Children and Adolescents with Autism Spectrum Disorder and Attention Deficit Hyperactivity Disorder
Internet Gaming Disorder in Children and Adolescents with Autism Spectrum Disorder and Attention Deficit Hyperactivity Disorder Open
Attention deficit hyperactivity disorder (ADHD) and autism spectrum disorder (ASD) have been related to an increased risk for behavioral addictions including online gaming. However, the relationship between these two conditions and Interne…
View article: Impact of Antibiotic Therapy in Patients with Cholangiocarcinoma Treated with Chemoimmunotherapy
Impact of Antibiotic Therapy in Patients with Cholangiocarcinoma Treated with Chemoimmunotherapy Open
View article: Contemporary diagnosis and treatment of conduct disorder in youth
Contemporary diagnosis and treatment of conduct disorder in youth Open
Due to its clinical heterogeneity, relevant subtypes of CD should be carefully characterized to gain reliable information on prognosis and treatments. Thus, disentangling this broad category in subtypes is crucial as a first step in diagno…
View article: Hikikomori (Severe Social Withdrawal) in Italian Adolescents: Clinical Features and Follow-Up
Hikikomori (Severe Social Withdrawal) in Italian Adolescents: Clinical Features and Follow-Up Open
Severe social withdrawal, including staying alone in one’s bedroom, non-attendance at school or work, and minimal or absent social contacts, sometimes only through electronic devices, can be found in several psychiatric disorders, or in a …
View article: Tempering expectations: considerations on the current state of stem cells therapy for autism treatment
Tempering expectations: considerations on the current state of stem cells therapy for autism treatment Open
OPINION article Front. Psychiatry, 03 October 2023Sec. Autism Volume 14 - 2023 | https://doi.org/10.3389/fpsyt.2023.1287879
View article: Emotion Recognition and Processing Deficits in Children with High Callous-Unemotional Traits: The Role of the MAOA Gene
Emotion Recognition and Processing Deficits in Children with High Callous-Unemotional Traits: The Role of the MAOA Gene Open
Children with high Callous-Unemotional (CU) traits show deficits in recognizing and processing facial expressions. Alterations in emotion recognition have been linked to a higher synaptic concentration of monoaminergic neurotransmitters. T…
View article: Psychopathic Traits, Externalizing Problems, and Prosocial Behavior: The Role of Social Dominance Orientation
Psychopathic Traits, Externalizing Problems, and Prosocial Behavior: The Role of Social Dominance Orientation Open
Psychopathic traits in community and referred youths are strongly associated with severe externalizing problems and low prosocial behavior. However, less is known about the mechanisms that may link youth psychopathy and these outcomes. Soc…
View article: Persistent Non-Suicidal Self-Injury and Suicidality in Referred Adolescents: A Longitudinal Study Exploring the Role of Cyclothymic Temperament
Persistent Non-Suicidal Self-Injury and Suicidality in Referred Adolescents: A Longitudinal Study Exploring the Role of Cyclothymic Temperament Open
Non-suicidal self-injury (NSSI) is deliberate harm to the body surface without suicidal intent, though it may be a predictor of suicide attempts. Our aim was to test the hypothesis that persisting and recovering NSSI may have a different l…
View article: P71 SGLT2I IN THE REAL WORLD: DATA FROM THE PONTE (BRIDGE) HF PROJECT (PDTA FOR INTEGRATED TERRITORY HOSPITAL FOLLOW–UP OF PATIENTS WITH HEART FAILURE)
P71 SGLT2I IN THE REAL WORLD: DATA FROM THE PONTE (BRIDGE) HF PROJECT (PDTA FOR INTEGRATED TERRITORY HOSPITAL FOLLOW–UP OF PATIENTS WITH HEART FAILURE) Open
Background The DAPA–HF and the EMPEROR reduced trials showed that sodium–glucose cotransporter type 2 inhibitors (SGLT2i) dapagliflozin and empagliflozin, on best medical therapy, resulted in a reduced incidence of the combined primary out…