Gabrielle Devienne
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View article: Beyond seizure control: identifying deficits in cognitive networks in absence seizure
Beyond seizure control: identifying deficits in cognitive networks in absence seizure Open
Absence epilepsy is frequently associated with cognitive impairments, yet the direct or indirect involvement of cognitive circuits remains poorly understood, as spike-and-wave discharges are rarely reported in these regions. Here, we inves…
View article: Synaptic cell adhesion molecule Cdh6 identifies a class of sensory neurons with novel functions in colonic motility
Synaptic cell adhesion molecule Cdh6 identifies a class of sensory neurons with novel functions in colonic motility Open
Intrinsic sensory neurons are an essential part of the enteric nervous system (ENS) and play a crucial role in gastrointestinal tract motility and digestion. Neuronal subtypes in the ENS have been distinguished by their electrophysiologica…
View article: The reuniens thalamus recruits recurrent excitation in the medial prefrontal cortex
The reuniens thalamus recruits recurrent excitation in the medial prefrontal cortex Open
The medial prefrontal cortex (mPFC) and hippocampus are critical for memory retrieval, decision making, and emotional regulation. While ventral CA1 (vCA1) shows direct and reciprocal connections with mPFC, dorsal CA1 (dCA1) forms indirect …
View article: Synaptic cell adhesion molecule Cdh6 identifies a class of sensory neurons with novel functions in colonic motility
Synaptic cell adhesion molecule Cdh6 identifies a class of sensory neurons with novel functions in colonic motility Open
Intrinsic sensory neurons are an essential part of the enteric nervous system (ENS) and play a crucial role in gastrointestinal tract motility and digestion. Neuronal subtypes in the ENS have been distinguished by their electrophysiologica…
View article: Synaptic cell adhesion molecule Cdh6 identifies a class of sensory neurons with novel functions in colonic motility
Synaptic cell adhesion molecule Cdh6 identifies a class of sensory neurons with novel functions in colonic motility Open
Intrinsic sensory neurons are an essential part of the enteric nervous system (ENS) and play a crucial role in gastrointestinal tract motility and digestion. Neuronal subtypes in the ENS have been distinguished by their electrophysiologica…
View article: Synaptic cell adhesion molecule Cdh6 identifies a class of sensory neurons with novel functions in colonic motility
Synaptic cell adhesion molecule Cdh6 identifies a class of sensory neurons with novel functions in colonic motility Open
Intrinsic sensory neurons are an essential part of the enteric nervous system (ENS) and play a crucial role in gastrointestinal tract motility and digestion. Neuronal subtypes in the ENS have been distinguished by their electrophysiologica…
View article: Synaptic cell adhesion molecule <i>Cdh6</i> identifies a class of sensory neurons with novel functions in colonic motility
Synaptic cell adhesion molecule <i>Cdh6</i> identifies a class of sensory neurons with novel functions in colonic motility Open
Intrinsic sensory neurons are an essential part of the enteric nervous system (ENS) and play a crucial role in gastrointestinal tract motility and digestion. Neuronal subtypes in the ENS have been distinguished by their electrophysiologica…
View article: Reuniens thalamus recruits recurrent excitation in medial prefrontal cortex
Reuniens thalamus recruits recurrent excitation in medial prefrontal cortex Open
Medial prefrontal cortex (mPFC) and hippocampus are critical for memory retrieval, decision making and emotional regulation. While ventral CA1 (vCA1) shows direct and reciprocal connections with mPFC, dorsal CA1 (dCA1) forms indirect pathw…
View article: Parvalbumin interneuron-derived tissue-type plasminogen activator shapes perineuronal net structure
Parvalbumin interneuron-derived tissue-type plasminogen activator shapes perineuronal net structure Open
Background Perineuronal nets (PNNs) are specialized extracellular matrix structures mainly found around fast-spiking parvalbumin (FS-PV) interneurons. In the adult, their degradation alters FS-PV-driven functions, such as brain plasticity …
View article: Regulation of Perineuronal Nets in the Adult Cortex by the Activity of the Cortical Network
Regulation of Perineuronal Nets in the Adult Cortex by the Activity of the Cortical Network Open
Perineuronal net (PNN) accumulation around parvalbumin-expressing (PV) inhibitory interneurons marks the closure of critical periods of high plasticity, whereas PNN removal reinstates juvenile plasticity in the adult cortex. Using targeted…
View article: Precise spatiotemporal control of voltage-gated sodium channels by photocaged saxitoxin
Precise spatiotemporal control of voltage-gated sodium channels by photocaged saxitoxin Open
Summary Here we report the pharmacologic blockade of voltage-gated sodium ion channels (NaV) by a synthetic saxitoxin derivative affixed to a photocleavable protecting group. We demonstrate that a functionalized saxitoxin (STX-eac) enables…
View article: Regulation of perineuronal nets in the adult cortex by the electrical activity of parvalbumin interneurons
Regulation of perineuronal nets in the adult cortex by the electrical activity of parvalbumin interneurons Open
Perineuronal net (PNN) accumulation around parvalbumin-expressing (PV) inhibitory interneurons marks the closure of critical periods of high plasticity, whereas PNN removal reinstates juvenile plasticity in the adult cortex. Using targeted…
View article: Single Cell Multiplex Reverse Transcription Polymerase Chain Reaction After Patch-clamp
Single Cell Multiplex Reverse Transcription Polymerase Chain Reaction After Patch-clamp Open
The cerebral cortex is composed of numerous cell types exhibiting various morphological, physiological, and molecular features. This diversity hampers easy identification and characterization of these cell types, prerequisites to study the…
View article: Depdc5 knockdown causes <scp>mTOR</scp>‐dependent motor hyperactivity in zebrafish
Depdc5 knockdown causes <span>mTOR</span>‐dependent motor hyperactivity in zebrafish Open
Objective DEPDC 5 was identified as a major genetic cause of focal epilepsy with deleterious mutations found in a wide range of inherited forms of focal epilepsy, associated with malformation of cortical development in certain cases. Ident…