Gaihua Zhang
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View article: Colicins of Escherichia coli Lead to Resistance against the Diarrhea-Causing Pathogen Enterotoxigenic E. coli in Pigs
Colicins of Escherichia coli Lead to Resistance against the Diarrhea-Causing Pathogen Enterotoxigenic E. coli in Pigs Open
This study revealed the heterogeneity of E. coli strains from pigs, including two strains studied by both in silico and wet experiments in detail and 14 strains studied by bioinformatics analysis. E. coli Y18J may improve the adaptability …
View article: Antioxidant potential of Pediococcus pentosaceus strains from the sow milk bacterial collection in weaned piglets
Antioxidant potential of Pediococcus pentosaceus strains from the sow milk bacterial collection in weaned piglets Open
Background In modern animal husbandry, breeders pay increasing attention to improving sow nutrition during pregnancy and lactation to favor the health of neonates. Sow milk is a main food source for piglets during their first three weeks o…
View article: vsRNAfinder: a novel method for identifying high-confidence viral small RNAs from small RNA-Seq data
vsRNAfinder: a novel method for identifying high-confidence viral small RNAs from small RNA-Seq data Open
Virus-encoded small RNAs (vsRNA) have been reported to play an important role in viral infection. Unfortunately, there is still a lack of an effective method for vsRNA identification. Herein, we presented vsRNAfinder, a de novo method for …
View article: Additional file 4 of Antioxidant potential of Pediococcus pentosaceus strains from the sow milk bacterial collection in weaned piglets
Additional file 4 of Antioxidant potential of Pediococcus pentosaceus strains from the sow milk bacterial collection in weaned piglets Open
Additional file 4: Figure S5. The annotation and comparison of P. pentosaceus SMM914 genome. (a) The distribution of predicted CDSs of P. pentosaceus SMM914 in different categories of metabolic function by the online software RAST. (b) A f…
View article: Additional file 1 of Antioxidant potential of Pediococcus pentosaceus strains from the sow milk bacterial collection in weaned piglets
Additional file 1 of Antioxidant potential of Pediococcus pentosaceus strains from the sow milk bacterial collection in weaned piglets Open
Additional file 1: Figure S1. The maximum-likelihood tree of the bacterial taxa. The 16S rRNA gene sequences from the isolates were clustered into 271 taxa with a similarity cut-off of 99% using CD-HIT. The closest related species of each …
View article: Additional file 5 of Antioxidant potential of Pediococcus pentosaceus strains from the sow milk bacterial collection in weaned piglets
Additional file 5 of Antioxidant potential of Pediococcus pentosaceus strains from the sow milk bacterial collection in weaned piglets Open
Additional file 5: Figure S6. Effects of P. pentosaceus SMM914 on (a) growth performance, (b) organ relative weight and intestine length in piglets. Data are the mean ± s.e.m. Statistical analysis was conducted by using one-way ANOVA. Data…
View article: Additional file 3 of Antioxidant potential of Pediococcus pentosaceus strains from the sow milk bacterial collection in weaned piglets
Additional file 3 of Antioxidant potential of Pediococcus pentosaceus strains from the sow milk bacterial collection in weaned piglets Open
Additional file 3: Figure S3. The antimicrobial activity of SMM914. (a) The pH of SMM914 products were determined via test papers. (b) Inhibitory effects of SMM914 against S. aureus and enterotoxigenic E. coli. The circular wells were fill…
View article: Additional file 6 of Antioxidant potential of Pediococcus pentosaceus strains from the sow milk bacterial collection in weaned piglets
Additional file 6 of Antioxidant potential of Pediococcus pentosaceus strains from the sow milk bacterial collection in weaned piglets Open
Additional file 6: Figure S9. (a) Alpha diversity comparisons of the gut microbiomes including Ace, Chao, Sobs index, Shannon index, Shannoneven index, Simpson index, Simpsoneven index and Faith's phylogenetic diversity index which were an…
View article: Additional file 2 of Antioxidant potential of Pediococcus pentosaceus strains from the sow milk bacterial collection in weaned piglets
Additional file 2 of Antioxidant potential of Pediococcus pentosaceus strains from the sow milk bacterial collection in weaned piglets Open
Additional file 2: Figure S2. Light microscopy images of P. pentosaceus strains with strong antimicrobial activity under a 63x oil immersion objective. Supplementary Data 2. The alignment of 1240 16S rRNA gene sequences against the Silva v…
View article: Antioxidant Potential of Pediococcus Pentosaceus Strains from the Sow Milk Bacterial Collection in Weaned Piglets
Antioxidant Potential of Pediococcus Pentosaceus Strains from the Sow Milk Bacterial Collection in Weaned Piglets Open
Background: In modern animal husbandry, breeders pay increasing attention to improving sow nutrition during pregnancy and lactation to favor the health of neonates. Sow milk is a main food for piglets during their first three weeks of life…
View article: Antioxidant Potential of Pediococcus Pentosaceus Strains From the Sow Milk Bacterial Collection in Weaned Piglets
Antioxidant Potential of Pediococcus Pentosaceus Strains From the Sow Milk Bacterial Collection in Weaned Piglets Open
Background: In modern animal husbandry, the relationship between sow and piglets is closely linked as breeders pay more attention to improving sow nutrition during pregnancy and lactation to favor the growing of neonates. Sow milk is the m…
View article: An Anti-Cancer Peptide LVTX-8 Inhibits the Proliferation and Migration of Lung Tumor Cells by Regulating Causal Genes’ Expression in p53-Related Pathways
An Anti-Cancer Peptide LVTX-8 Inhibits the Proliferation and Migration of Lung Tumor Cells by Regulating Causal Genes’ Expression in p53-Related Pathways Open
Spider venom has been found to show its anticancer activity in a variety of human malignancies, including lung cancer. In this study, we investigated the anti-cancer peptide toxin LVTX-8, with linear amphipathic alpha-helical conformation,…
View article: Homologous recombination shapes the genetic diversity of African swine fever viruses
Homologous recombination shapes the genetic diversity of African swine fever viruses Open
View article: Rapid identification of human‐infecting viruses
Rapid identification of human‐infecting viruses Open
Viruses have caused much mortality and morbidity to humans and pose a serious threat to global public health. The virome with the potential of human infection is still far from complete. Novel viruses have been discovered at an unprecedent…
View article: Identification of viruses with the potential to infect human
Identification of viruses with the potential to infect human Open
The virus has caused much mortality and morbidity to humans, and still posed a serious threat to the global public health. The virome with the human-infection potential is far from complete. Novel viruses have been discovered at an unprece…
View article: Prediction of antiviral drugs against African Swine Fever Viruses based on protein-protein interaction analysis
Prediction of antiviral drugs against African Swine Fever Viruses based on protein-protein interaction analysis Open
The African swine fever virus (ASFV) has severely influenced the swine industry of the world. Unfortunately, there is no effective antiviral drug or vaccine against the virus until now. Identification of new anti-ASFV drugs is urgently nee…
View article: RAEdb: a database of enhancers identified by high-throughput reporter assays
RAEdb: a database of enhancers identified by high-throughput reporter assays Open
High-throughput reporter assays have been recently developed to directly and quantitatively assess enhancer activity for thousands of regulatory elements. However, there is still no database to collect these enhancers. We developed RAEdb, …
View article: Lenalidomide following fludarabine and rituximab in previously untreated CLL
Lenalidomide following fludarabine and rituximab in previously untreated CLL Open
Fludarabine-based regimens have overall response rates (ORR) of 90-95% in untreated chronic lymphocytic leukemia (CLL), but almost all patients inevitably relapse.Given the promising activity of lenalidomide in relapsed/refractory CLL, we …