Gail Whiting
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View article: Tackling immunosuppression by Neisseria gonorrhoeae to facilitate vaccine design
Tackling immunosuppression by Neisseria gonorrhoeae to facilitate vaccine design Open
Gonorrhoea, caused by Neisseria gonorrhoeae , is a common sexually transmitted infection. Increasing multi-drug resistance and the impact of asymptomatic infections on sexual and reproductive health underline the need for an effective gono…
View article: Corrected and Republished from: “A Novel, Multiple-Antigen Pneumococcal Vaccine Protects against Lethal<i>Streptococcus pneumoniae</i>Challenge”
Corrected and Republished from: “A Novel, Multiple-Antigen Pneumococcal Vaccine Protects against Lethal<i>Streptococcus pneumoniae</i>Challenge” Open
Current vaccination against Streptococcus pneumoniae uses vaccines based on capsular polysaccharides from selected serotypes and has led to nonvaccine serotype replacement disease. We have investigated an alternative serotype-independent a…
View article: Quantification of FAM20A in human milk and identification of calcium metabolism proteins
Quantification of FAM20A in human milk and identification of calcium metabolism proteins Open
Using mass spectrometry-driven proteomics, we successfully quantified FAM20A from transitional to mature milk and obtained a list of proteins involved in calcium metabolism. Furthermore, we show the value of using a combination of both sho…
View article: Factor H binding protein (fHbp)-mediated differential complement resistance of a serogroup C Neisseria meningitidis isolate from cerebrospinal fluid of a patient with invasive meningococcal disease
Factor H binding protein (fHbp)-mediated differential complement resistance of a serogroup C Neisseria meningitidis isolate from cerebrospinal fluid of a patient with invasive meningococcal disease Open
During an outbreak of invasive meningococcal disease (IMD) at the University of Southampton, UK, in 1997, two Neisseria meningitidis serogroup C isolates were retrieved from a student (‘Case’), who died of IMD, and a close contact (‘Carrie…
View article: Typing complex meningococcal vaccines to understand diversity and population structure of key vaccine antigens
Typing complex meningococcal vaccines to understand diversity and population structure of key vaccine antigens Open
Background:Protein-conjugate capsular polysaccharide vaccines can potentially control invasive meningococcal disease (IMD) caused by five (A, C, W, X, Y) of the six IMD-associated serogroups. Concerns raised by immunological similarity of …
View article: A Novel, Multiple-Antigen Pneumococcal Vaccine Protects against Lethal<i>Streptococcus pneumoniae</i>Challenge
A Novel, Multiple-Antigen Pneumococcal Vaccine Protects against Lethal<i>Streptococcus pneumoniae</i>Challenge Open
Current vaccination against Streptococcus pneumoniae uses vaccines based on capsular polysaccharides from selected serotypes and has led to nonvaccine serotype replacement disease. We have investigated an alternative serotype-independent a…
View article: Typing complex meningococcal vaccines to understand diversity and population structure of key vaccine antigens
Typing complex meningococcal vaccines to understand diversity and population structure of key vaccine antigens Open
Background:Protein-conjugate capsular polysaccharide vaccines can potentially control invasive meningococcal disease (IMD) caused by five (A, C, W, X, Y) of the six IMD-associated serogroups. Concerns raised by immunological similarity of …