Explanipedia

Mechanistic Modeling of Continuous Lyophilization for Biopharmaceutical Manufacturing Open

Prakitr Srisuma, Gang Chen, Richard D. Braatz · 2025

Lyophilization (aka freeze drying) is a typical process in (bio)pharmaceutical manufacturing used for improving the stability of various drug products, including its recent applications to mRNA vaccines. While extensive efforts are dedicat…

Analysis and Optimization of Wellbore Structure Considering Casing Stress in Oil and Gas Wells Within Coal Mine Goaf Areas Subject to Overburden Movement Open

Fangchao Tong, Gang Chen, Mingming Tang, Yongbo Cao, Yinping Cao , et al. · 2025

To address wellbore integrity issues (especially casing strength concerns) of oil and gas wells threatened by overburden movement in coal mine goafs, this study takes a gas well in the goaf of Yanchang Gas Field as the research object. Usi…

Spatiotemporal Mapping of Anisotropic Thermal Transport in GaN Thin Films via Ultrafast X-ray Diffraction Open

Mingda Li, Nguyễn Thanh Tùng, Chu-Liang Fu, Mouyang Cheng, Buxuan Li , et al. · 2025

Efficient thermal management is essential for the reliability of modern power electronics, where increasing device density leads to severe heat dissipation challenges. However, in thin-film systems, thermal transport is often compromised b…

Time Crystal in the Nonlinear Phonon Mode of the Trapped Ions Open

Yiqiang Zhan, Chunfu Liu, Jintao Bu, Kaifeng Cui, Shi‐Lei Su , et al. · 2025

Time crystals constitute a novel phase of matter defined by the spontaneous breaking of timetranslation symmetry. Here we present a scheme to realize a continuous-time crystal of the vibrational phonon in the normal mode of two coupled ult…

Sub-diffraction limited focusing with quasi-periodic photonic crystal multilayers Open

Hang Xue, Yanyan Zhou, Wenpeng Zhang, Yixuan Zhou, Jin Xiang , et al. · 2025

Direct writing lithography plays a crucial role in the fabrication of arbitrary nano-patterns. In order to improve the resolution, a quasi-periodic photonic crystal (QPC) multilayer structure is proposed for manipulating the evanescent wav…

Role of cell cycle-related gene SAC3 domain containing 1 as a potential target of nitidine chloride in hepatocellular carcinoma progression Open

Qing-Ling Huang, Shengsheng Zhou, Jian‐Di Li, Dandan Xiong, Rong‐Quan He , et al. · 2025

BACKGROUND Hepatocellular carcinoma (HCC) is at the forefront of the global spectrum of cancer incidence and mortality, with conventional therapies like tyrosine kinase inhibitors limited by resistance. Recent studies have highlighted the …

Low-Refractive-Index SiO2 Nanocolumnar Thin Films Fabricated by Oblique Angle Deposition Open

Bojie Jia, Gang Chen, Sheng Zhou, Xiaofeng Ma, Qiuyu Zhang , et al. · 2025

The refractive index is one of the most important optical parameters of optical thin films. Optical films with a low refractive index can effectively reduce the residual reflection on the film surface, which is one of the most important pa…

Evaporative Refrigeration Effect in Evaporation and Condensation between Two Parallel Plates Open

P. Chen, Qin Li, Gang Chen · 2025

It is well-known that evaporation can lead to cooling. However, little is known that evaporation can actually create a refrigeration effect, i.e., the vapor phase temperature can drop below the temperature of the cooling wall. This possibi…

Reply to Ahmed and Lu: Cluster signals depend on how samples are made and measured Open

Gang Chen, Guangxin Lv, James H. Zhang, Yaodong Tu · 2025

Design and Performance Study of Plate-Fin Phase-Change Heat Storage Heat Exchanger for High-Power Space Loads Open

Lei Cao, Liyao Zhu, Luotong Fu, Gang Chen, Shuye Ding , et al. · 2025

Experimental Investigation of Fracture Propagation Induced by Supercritical CO2 in Deep Shale Reservoirs Open

Tingting Shen, Gang Chen, Jiang Bai, Dan Zhang · 2025

An On-Orbit Calibration Model for Full-Waveform Laser Altimeters by Matching Single-Modal and Multimodal Waveforms Open

Qi Xu, Huan Xie, Peiqi Huang, Min Ji, Hao Wu , et al. · 2024

Accurate pointing and ranging calibration are essential for laser altimeters to obtain the geolocation accuracy required for further scientific application. Waveform matching is an economical and effective on-orbit calibration technique th…

ACTR10 Overexpression Facilitates the Progression and Tyrosine Kinase Inhibitor Resistance in Hepatocellular Carcinoma Open

Jie Luo, Kai Qin, Rong‐Rong He, Jian Di Li, Zhimin Huang , et al. · 2024

The upregulation of ACTR10 accelerates HCC progression, promotes TKI resistance, and emerges as a prospective target for the treatment of HCC.

Variation of six local poplar clones in growth and eco-physiological traits in two types of arid valleys Open

Liang Mao, Jie Liu, Xiang Xiang, Feifei Tian, Yang Liu , et al. · 2024

The ecologically fragile arid valleys in western China have low afforestation survival rates, and the lack of adaptable superior variety is key to restricting forestry production and ecological restoration in this region. The native poplar…

Unified physio-thermodynamic descriptors via learned CO2 adsorption properties in metal-organic frameworks Open

Emily Lın, Yang Zhong, Gang Chen, Sili Deng · 2024

The continual growth of anthropogenic CO₂ has motivated the introduction of carbon capture techniques, such as metal-organic framework (MOF)-based physisorption. The large design space of adsorbents resulting from the inherently…

Artificial superconducting Kondo lattice in a van der Waals heterostructure Open

Kai Fan, Heng Jin, Bing Huang, Guijing Duan, Rong Yu , et al. · 2024

Engineering Kondo lattice with tailored functionality is desirable for elucidating the heavy fermion physics. We realize the construction of an artificial Kondo lattice/superconductor heterojunction by growing monolayer VSe 2 on bulk 2H-Nb…

Modeling photomolecular effect using generalized boundary conditions for Maxwell equations Open

Gang Chen · 2024

We recently demonstrated via experiments in hydrogels and at a single air-water interface the photomolecular effect: photons directly cleaving off water molecular clusters in the visible spectrum where bulk water has negligible absorption.…

Real-time Thermal Error Compensation of Machine Tools Based on Machine Learning Model and Actual Cutting Measurement via Temperature Sensors Open

Gang Chen, Kun-Chieh Wang · 2024

Nonreciprocal reflection of mid-infrared light by highly doped InAs at low magnetic fields Open

Simo Pajovic, Yoichiro Tsurimaki, Xin Qian, Gang Chen, Svetlana V. Boriskina · 2024

We report an experimental observation of room-temperature nonreciprocal reflection of mid-infrared light from planar highly doped InAs surfaces at low magnetic fields ranging from 0.07 T to 0.16 T. Using ellipsometry, we demonstrate that t…

Author Correction: Reversible two-way tuning of thermal conductivity in an end-linked star-shaped thermoset Open

Chase M. Hartquist, Buxuan Li, James H. Zhang, Zhaohan Yu, Guangxin Lv , et al. · 2024

Reversible two-way tuning of thermal conductivity in an end-linked star-shaped thermoset Open

Chase M. Hartquist, Buxuan Li, James H. Zhang, Zhaohan Yu, Guangxin Lv , et al. · 2024

Dynamics of Spinning Binary at 2PM Open

Gang Chen, Tianheng Wang · 2024

We consider the covariant proposal for the gravitational Compton amplitude for a Kerr black hole. Employing the covariant three- and four-point Compton amplitudes, we assemble the classical one-loop integrand on the maximal cut at all orde…

Static Equivalence Method of Power Grid Based on Genetic Algorithm Open

Xiaofeng Jiang, Pengyu Pan, Hao Wang, Lei Liu, Gang Chen , et al. · 2024

When the electromagnetic transient simulation of a large-scale power grid is carried out, because the simulation is limited by the scale of simulation software, it is necessary to divide the grid into internal and external grids, and the e…

Photomolecular effect: Visible light interaction with air–water interface Open

Guangxin Lv, Yaodong Tu, James H. Zhang, Gang Chen · 2024

Although water is almost transparent to visible light, we demonstrate that the air–water interface interacts strongly with visible light via what we hypothesize as the photomolecular effect. In this effect, transverse-magnetic polarized ph…

Dynamic water absorption-desorption by aqueous salt solutions Open

Carlos D. Díaz‐Marín, Akshay Deshmukh, Miles A. Roper, John H. Lienhard, Gang Chen · 2024

Salt solutions have attracted significant interest as water sorbents for a wide range of applications due to their large hygroscopicity and low cost. However, despite their promise, no existing model fully describes the experimentally obse…

A Metastructure Based on Amorphous Carbon for High Efficiency and Selective Solar Absorption Open

Junli Su, Gang Chen, Chong Ma, Qiuyu Zhang, Xingyu Li , et al. · 2024

Efficient solar thermal conversion is crucial for renewable clean energy technologies such as solar thermal power generation, solar thermophotovoltaic and seawater desalination. To maximize solar energy conversion efficiency, a solar selec…

Exploration of the Symmetry and Asymmetry of the Proton Electric Field Ep and Electron Electric Field Ee Open

Gang Chen · 2024

The classical electric field theory does not indicate the effect of temperature on the proton and electron electric fields or explain the differences between the proton and electron electric fields. The Epe value determines the radius r an…

Demand-side response power control strategy considering load production sequence requirements Open

Xi Wang, Zhe Chen, Haocong Xie, Siyang Liao, Xi Ye , et al. · 2024

With the introduction of a high proportion of new energy sources, the power system needs new means to enhance its regulating flexibility. High-energy-consuming industrial loads on the demand side have significant potential to improve the g…

Method of Multi-Energy Complementary System Participating in Auxiliary Frequency Regulation of Power Systems Open

Dawei Zhang, Gang Chen, Guo Guo, Yongcan Wang, Feipeng Lv , et al. · 2024

This research investigates a grid with two areas interconnected by a high-voltage direct-current (DC) link. One of the areas, called the sending-end region, has intermittent renewable generation and frequency stability issues. To address t…

Real-Time Hybrid Test Method for Floating Wind Turbines: Focusing on the Aerodynamic Load Identification Open

Binrong Wen, Zhihao Jiang, Xinliang Tian, Gang Chen, Jun Li , et al. · 2024

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