Gangling Tong
YOU?
Author Swipe
View article: B1 corrected T1 mapping in the differentiation and prediction of breast cancer
B1 corrected T1 mapping in the differentiation and prediction of breast cancer Open
View article: Cadonilimab combined with trastuzumab and chemotherapy for HER2-positive gastric cancer with bone marrow metastasis and DIC: a case report and literature review
Cadonilimab combined with trastuzumab and chemotherapy for HER2-positive gastric cancer with bone marrow metastasis and DIC: a case report and literature review Open
Background Gastric cancer (GC) is one of the most common malignancies worldwide. While bone marrow metastasis (BMM) in GC is extremely rare and often complicated by disseminated intravascular coagulation (DIC), a critical condition with a …
View article: Hsa_circ_0002238 promotes the malignant behavior of colorectal cancer
Hsa_circ_0002238 promotes the malignant behavior of colorectal cancer Open
Background Colorectal cancer (CRC) is one of the most common and deadly cancers worldwide. Circular RNAs (circRNAs) have emerged as crucial players in the onset and progression of CRC. This research aims to investigate the expression level…
View article: Adverse events associated with hepatic arterial infusion chemotherapy and its combination therapies in hepatocellular carcinoma: a systematic review
Adverse events associated with hepatic arterial infusion chemotherapy and its combination therapies in hepatocellular carcinoma: a systematic review Open
Background Hepatic arterial infusion chemotherapy (HAIC) has emerged as a promising treatment for unresectable hepatocellular carcinoma (HCC). However, the safety profiles of HAIC and its various combination therapies remain to be systemat…
View article: Prognostic value of inflammatory and nutritional indexes among patients with unresectable advanced gastric cancer receiving immune checkpoint inhibitors combined with chemotherapy—a retrospective study
Prognostic value of inflammatory and nutritional indexes among patients with unresectable advanced gastric cancer receiving immune checkpoint inhibitors combined with chemotherapy—a retrospective study Open
Background Recent studies have revealed that inflammatory factors and nutritional status of patients with advanced gastric cancer (AGC) are related to the efficacy of drug therapy and patient prognosis. This study seeks to evaluate the cor…
View article: Corrigendum to “SOX8 promotes tumor growth and metastasis through FZD6-dependent Wnt/β-catenin signaling in colorectal carcinoma” [Heliyon 9(12) (December 2023) e22586]
Corrigendum to “SOX8 promotes tumor growth and metastasis through FZD6-dependent Wnt/β-catenin signaling in colorectal carcinoma” [Heliyon 9(12) (December 2023) e22586] Open
[This corrects the article DOI: 10.1016/j.heliyon.2023.e22586.].
View article: SOX8 promotes tumor growth and metastasis through FZD6-dependent Wnt/β-catenin signaling in colorectal carcinoma
SOX8 promotes tumor growth and metastasis through FZD6-dependent Wnt/β-catenin signaling in colorectal carcinoma Open
View article: Immune activity score to assess the prognosis, immunotherapy and chemotherapy response in gastric cancer and experimental validation
Immune activity score to assess the prognosis, immunotherapy and chemotherapy response in gastric cancer and experimental validation Open
Background Gastric cancer (GC) is an extremely heterogeneous malignancy with a complex tumor microenvironment (TME) that contributes to unsatisfactory prognosis. Methods The overall activity score for assessing the immune activity of GC pa…
View article: IL23R as an indicator of immune infiltration and poor prognosis in intrahepatic cholangiocarcinoma: a bioinformatics analysis
IL23R as an indicator of immune infiltration and poor prognosis in intrahepatic cholangiocarcinoma: a bioinformatics analysis Open
A circRNA-miRNA-IL23R network was identified, and it was found that IL23R may be a prognostic and immune-related biomarker in CHOL, which is worthy of further exploration.
View article: Risk Factors of Gastrointestinal Perforation with a Poor Prognosis
Risk Factors of Gastrointestinal Perforation with a Poor Prognosis Open
Our research found that the perforation site, total protein, albumin, hemoglobin, NLR, LMR, PLR and PNI were risk factors for gastrointestinal perforation with a poor prognosis.
View article: Pre-treatment Body Mass Index as a Predictive Biomarker for Immunotherapy Outcomes in Advanced Lung Cancer
Pre-treatment Body Mass Index as a Predictive Biomarker for Immunotherapy Outcomes in Advanced Lung Cancer Open
Objectives To analyze the clinicopathological parameters of advanced lung cancer patients who received Immune checkpoint inhibitors (ICIs) treatment to establish pre-treatment body mass index (BMI) as a predictor of immunotherapy response,…
View article: Intratumoral CD8+ T cells as a potential positive predictor of chemoimmunotherapy response in PD-L1-negative advanced gastric cancer patients: a retrospective cohort study
Intratumoral CD8+ T cells as a potential positive predictor of chemoimmunotherapy response in PD-L1-negative advanced gastric cancer patients: a retrospective cohort study Open
Intratumoral CD8+ TILs may be a potential positive predictive factor of clinical response for chemoimmunotherapy in PD-L1-negative advanced GC. However, the results need to be further confirmed in a cohort with more subjects due…
View article: Association of neutralizing breadth against SARS-CoV-2 with inoculation orders of heterologous prime-boost vaccines
Association of neutralizing breadth against SARS-CoV-2 with inoculation orders of heterologous prime-boost vaccines Open
View article: Treatment efficacy and prognosis analysis in locally advanced or metastatic colorectal cancer patients with hydronephrosis
Treatment efficacy and prognosis analysis in locally advanced or metastatic colorectal cancer patients with hydronephrosis Open
The effect of hydronephrosis, a common complication of metastatic colorectal cancer (CRC), on the treatment outcome and prognosis of locally advanced or metastatic CRC remains to be elucidated. The present study investigated the clinical c…
View article: Prognostic impact of sarcopenia on immune-related adverse events in malignancies received immune checkpoint inhibitors: a systematic review and meta-analysis
Prognostic impact of sarcopenia on immune-related adverse events in malignancies received immune checkpoint inhibitors: a systematic review and meta-analysis Open
Malignancies with sarcopenia at pre-immunotherapy may not increase the incidence of irAEs, and sarcopenia may not be a predictive factor for irAEs.
View article: SARS-CoV-2 immunity and functional recovery of COVID-19 patients 1-year after infection
SARS-CoV-2 immunity and functional recovery of COVID-19 patients 1-year after infection Open
The long-term immunity and functional recovery after SARS-CoV-2 infection have implications in preventive measures and patient quality of life. Here we analyzed a prospective cohort of 121 recovered COVID-19 patients from Xiangyang, China …
View article: Prognostic Impact of Sarcopenia on Clinical Outcomes in Malignancies Treated With Immune Checkpoint Inhibitors: A Systematic Review and Meta-Analysis
Prognostic Impact of Sarcopenia on Clinical Outcomes in Malignancies Treated With Immune Checkpoint Inhibitors: A Systematic Review and Meta-Analysis Open
Background The effect of sarcopenia on the clinical outcomes of patients with malignant neoplasms receiving immune checkpoint inhibitors (ICIs) is unclear. The aim of this study was to evaluate the effect and survival of patients with mali…
View article: Clinical evidence of an interferon–glucocorticoid therapeutic synergy in COVID-19
Clinical evidence of an interferon–glucocorticoid therapeutic synergy in COVID-19 Open
Synthetic glucocorticoid dexamethasone is the first trial-proven drug that reduces COVID-19 mortality by suppressing immune system. In contrast, interferons are a crucial component of host antiviral immunity and can be directly suppressed …
View article: Upregulation of Small Nucleolar RNA 78 Promotes Cell Proliferation and Invasion of Breast Cancer
Upregulation of Small Nucleolar RNA 78 Promotes Cell Proliferation and Invasion of Breast Cancer Open
OBJECTIVE: Recent studies suggest that abnormal snoRNA expression may play crucial role in tumor development and progression. In the study, we aim to explore the clinical significance and functional role of Small nucleolar RNA 78 (SNORD78)…
View article: Retrospective Multicenter Cohort Study Shows Early Interferon Therapy Is Associated with Favorable Clinical Responses in COVID-19 Patients
Retrospective Multicenter Cohort Study Shows Early Interferon Therapy Is Associated with Favorable Clinical Responses in COVID-19 Patients Open
View article: <p>Efficacy of Olanzapine-Triple Antiemetic Regimen in Patients with Gastrointestinal Tumor and High Risk of Chemotherapy-Induced Nausea and Vomiting Receiving Moderately Emetogenic Chemotherapy: A Retrospective Study</p>
Efficacy of Olanzapine-Triple Antiemetic Regimen in Patients with Gastrointestinal Tumor and High Risk of Chemotherapy-Induced Nausea and Vomiting Receiving Moderately Emetogenic Chemotherapy: A Retrospective Study Open
This retrospective study indicates that in gastrointestinal tumor patients with high-risk factors for CINV who were receiving MEC, olanzapine-containing triple antiemetic regimen exhibit better efficacy and QoL as compared to non-olanzapin…
View article: Circulating tumor DNA clearance predicts prognosis across treatment regimen in a large real-world longitudinally monitored advanced non-small cell lung cancer cohort
Circulating tumor DNA clearance predicts prognosis across treatment regimen in a large real-world longitudinally monitored advanced non-small cell lung cancer cohort Open
This prospective real-world study shows that ctDNA clearance during treatment may serve as predictive and prognostic marker across a wide spectrum of treatment regimens.
View article: <p>Trastuzumab with FLOT Regimen for the Perioperative Treatment of Resectable HER2 + Advanced Gastric Cancer: A Retrospective Study</p>
Trastuzumab with FLOT Regimen for the Perioperative Treatment of Resectable HER2 + Advanced Gastric Cancer: A Retrospective Study Open
Trastuzumab combined with FLOT has a good curative effect and safety profile in the perioperative treatment of patients with resectable HER-2-positive advanced gastric cancer. In addition, trastuzumab + FLOT had the same result as FLOT alo…
View article: MACC1 regulates PDL1 expression and tumor immunity through the c‐Met/AKT/mTOR pathway in gastric cancer cells
MACC1 regulates PDL1 expression and tumor immunity through the c‐Met/AKT/mTOR pathway in gastric cancer cells Open
Background Immunotherapy and its mechanisms are being studied in a wide variety of cancers. Programmed cell death ligand 1 (PDL1) is associated with immune evasion in numerous tumor types. Here, we aimed to assess the relationship between …
View article: <p>Enumeration And Characterization Of Circulating Tumor Cells And Its Application In Advanced Gastric Cancer</p>
Enumeration And Characterization Of Circulating Tumor Cells And Its Application In Advanced Gastric Cancer Open
We provide a new method that allows for the simple and effective detection of CTCs in aGC. It has potential clinical applications in monitoring prognosis and guiding future individualized immunotherapy.
View article: P1.01-037 Circulating Tumor DNA Clearance During Treatment Associates with Improved Progression-Free Survival
P1.01-037 Circulating Tumor DNA Clearance During Treatment Associates with Improved Progression-Free Survival Open
View article: MiR-495-3p facilitates colon cancer cell proliferation via Wnt/β-catenin signaling pathway by restraining Wnt inhibitory factor
MiR-495-3p facilitates colon cancer cell proliferation via Wnt/β-catenin signaling pathway by restraining Wnt inhibitory factor Open
Purpose: To demonstrate whether miR-495-3p promote the occurrence of colon cancer and development of colon cancer stem cells by inhibiting Wnt inhibitory factor (WIF1).Methods: The level of MiRNA and mRNA in cells were tested by real-time …
View article: Knockdown of HOXA-AS2 suppresses proliferation and induces apoptosis in colorectal cancer.
Knockdown of HOXA-AS2 suppresses proliferation and induces apoptosis in colorectal cancer. Open
Colorectal cancer (CRC) remains one of the most common cancers worldwide. Increasing evidence indicates that long non-coding RNAs (lncRNAs) regulate diverse cellular processes, including cell growth, differentiation, apoptosis, and cancer …
View article: 498PD_PR Prevalence and types of distress among Adult and Young Adolescent (AYA) newly diagnosed with cancer in Singapore
498PD_PR Prevalence and types of distress among Adult and Young Adolescent (AYA) newly diagnosed with cancer in Singapore Open
View article: 498PD_PR Prevalence and types of distress among Adult and Young Adolescent (AYA) newly diagnosed with cancer in Singapore
498PD_PR Prevalence and types of distress among Adult and Young Adolescent (AYA) newly diagnosed with cancer in Singapore Open