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View article: Inflammatory Markers are Associated with Ischemic Stroke among Indigenous Africans: Evidence from the SIREN Study
Inflammatory Markers are Associated with Ischemic Stroke among Indigenous Africans: Evidence from the SIREN Study Open
Background: Inflammation might predispose to worse outcomes after an ischemic stroke. This has not been characterized among indigenous Africans. Purpose: We investigated the association between inflammatory biomarkers, stroke severity, and…
View article: Global, Regional, and National Burden of Nontraumatic Subarachnoid Hemorrhage
Global, Regional, and National Burden of Nontraumatic Subarachnoid Hemorrhage Open
Importance Nontraumatic subarachnoid hemorrhage (SAH) represents the third most common stroke type with unique etiologies, risk factors, diagnostics, and treatments. Nevertheless, epidemiological studies often cluster SAH with other stroke…
View article: May Measurement Month 2022: an analysis of blood pressure screening results from Nigeria
May Measurement Month 2022: an analysis of blood pressure screening results from Nigeria Open
The May Measurement Month (MMM) campaign was carried out in Nigeria in 2022 to raise awareness of high blood pressure (BP). Here, we report on the campaign’s findings. Adults aged ≥18 years were recruited opportunistically at public and pr…
View article: Antiplatelet resistance among a cohort of patients at risk of atherosclerotic cardiovascular diseases in Jos, Nigeria
Antiplatelet resistance among a cohort of patients at risk of atherosclerotic cardiovascular diseases in Jos, Nigeria Open
Objectives: Patients with atherosclerotic cardiovascular diseases (ASCVDs) are predisposed to atherothrombosis and ischemic phenomena. Antiplatelets mitigate this but not consistently, as these ischemic events still occur despite their adm…
View article: Factors associated with frequency of fruit and vegetable consumption among selected sub-Saharan African populations: evidence from the Cardiovascular H3Africa Innovation Resource Project
Factors associated with frequency of fruit and vegetable consumption among selected sub-Saharan African populations: evidence from the Cardiovascular H3Africa Innovation Resource Project Open
Background Frequent fruit and vegetable consumption is considered a promising dietary behaviour that protects health. However, most existing studies about the factors associated with this phenomenon among Africans are based on single-count…
View article: Estimating vaccine coverage in conflict settings using geospatial methods: a case study in Borno state, Nigeria
Estimating vaccine coverage in conflict settings using geospatial methods: a case study in Borno state, Nigeria Open
Reliable estimates of subnational vaccination coverage are critical to track progress towards global immunisation targets and ensure equitable health outcomes for all children. However, conflict can limit the reliability of coverage estima…
View article: Rationale, Design, and the Baseline Characteristics of the RHDGen (The Genetics of Rheumatic Heart Disease) Network Study†
Rationale, Design, and the Baseline Characteristics of the RHDGen (The Genetics of Rheumatic Heart Disease) Network Study† Open
Background: The genetics of rheumatic heart disease (RHDGen) Network was developed to assist the discovery and validation of genetic variations and biomarkers of risk for rheumatic heart disease (RHD) in continental Africans, as a part of …
View article: Chronic obstructive pulmonary disease in sub-Saharan Africa
Chronic obstructive pulmonary disease in sub-Saharan Africa Open
BACKGROUND: Chronic obstructive pulmonary disease (COPD) is the third leading cause of death worldwide and an important cause of death in sub-Saharan Africa (SSA). We conducted a systematic review and meta-analysis on the prevalence of and…
View article: Cardiovascular Risk Factors in HIV-Infected Adults in North-Central Nigeria: Prevalence, Associated Factors and Assessment of Risk Using the Framingham Risk Score – Preliminary Results from a Survey
Cardiovascular Risk Factors in HIV-Infected Adults in North-Central Nigeria: Prevalence, Associated Factors and Assessment of Risk Using the Framingham Risk Score – Preliminary Results from a Survey Open
HIV/AIDS is an increasingly important cause of cardiovascular (CVD) morbidity world-wide. We sought to evaluate the prevalence of CVD risk factors in HIV positive (HIV+) adults and assessment of these risks using the Framingham risk score …
View article: Left Ventricular Geometry and Function in Normotensive and Hypertensive Patients with Type 2 Diabetes Mellitus without Overt Cardiac Symptoms
Left Ventricular Geometry and Function in Normotensive and Hypertensive Patients with Type 2 Diabetes Mellitus without Overt Cardiac Symptoms Open
Cardiovascular disease (CVD) is a common cause of morbidity/mortality in patients with type 2 diabetes mellitus (T2DM). Echocardiography can detect changes in cardiac geometry/function before overt CVD symptoms. This study aimed to evaluat…
View article: Diabetic Foot Ulceration in a Secondary Health Facility
Diabetic Foot Ulceration in a Secondary Health Facility Open
Aims: To determine the prevalence, pattern and presentation of the diabetic foot ulcer.
Background: A diabetic foot ulcer is a major complication in diabetes mellitus and probably the major component of diabetic foot. It occurs in 15% of …
View article: Unraveling the risk factors for spontaneous intracerebral hemorrhage among West Africans
Unraveling the risk factors for spontaneous intracerebral hemorrhage among West Africans Open
Population-level control of the dominant factors will substantially mitigate the burden of sICH in West Africa.
View article: Elastomeric pump malfunction resulting in over-infusion of local anesthetic
Elastomeric pump malfunction resulting in over-infusion of local anesthetic Open
A 70 year-old female patient presented for a right humeral head replacement. Preoperatively an interscalene catheter was placed and postoperatively connected to an elastomeric pump for continuous infusion at 8 mL/h of Ropivacaine 0.2% with…
Knowledge, attitudes and practices related to stroke in Ghana and Nigeria: A SIREN call to action Open
The major findings illustrate the fears, causes, chief problems, treatment, and recommendations related to stroke through the views of the participants, as well as recommendations for working effectively with the SIREN communities. Finding…
View article: Prevalence of Type II Diabetes Mellitus (T2DM) andRisk Factors among Rural Farmers
Prevalence of Type II Diabetes Mellitus (T2DM) andRisk Factors among Rural Farmers Open
International audience
View article: Knowledge, attitudes and practices of West Africans on genetic studies of stroke: Evidence from the SIREN Study
Knowledge, attitudes and practices of West Africans on genetic studies of stroke: Evidence from the SIREN Study Open
Background It is crucial to assess genomic literacy related to stroke among Africans in preparation for the ethical, legal and societal implications of the genetic revolution which has begun in Africa. Objective To assess the knowledge, at…
View article: Prevalence and Prognostic Features of ECG Abnormalities in Acute Stroke: Findings From the SIREN Study Among Africans
Prevalence and Prognostic Features of ECG Abnormalities in Acute Stroke: Findings From the SIREN Study Among Africans Open
About 4 in 5 acute stroke patients in this African cohort had evidence of a baseline ECG abnormality, but presence of any atrial enlargement was the only independent ECG predictor of death or disability.
View article: Clinical Outcomes in 3343 Children and Adults With Rheumatic Heart Disease From 14 Low- and Middle-Income Countries
Clinical Outcomes in 3343 Children and Adults With Rheumatic Heart Disease From 14 Low- and Middle-Income Countries Open
Background: There are few contemporary data on the mortality and morbidity associated with rheumatic heart disease or information on their predictors. We report the 2-year follow-up of individuals with rheumatic heart disease from 14 low- …