Gaofei Jiang
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Chronic Obstructive Pulmonary Disease and Obstructive Sleep Apnea Coexistence: From Pathophysiology to Clinical Complications Open
Understanding the progression from localized AFL to systemic injury is essential for clarifying the full burden of OVS, particularly as it relates to its various comorbidities. Current evidence offers a basis for improving early identifica…
Urban soils amplify and homogenize bacterial zoonotic pathogens across multiple Chinese cities Open
Urbanisation is rapidly reshaping global landscapes, yet its impact on zoonotic pathogens in soil remains poorly understood. Here we investigated potential bacterial zoonotic pathogen distribution and diversity across four land use types (…
View article: LorBin: efficient binning of long-read metagenomes by multiscale adaptive clustering and evaluation
LorBin: efficient binning of long-read metagenomes by multiscale adaptive clustering and evaluation Open
Long-read sequencing has transformed metagenomics and improved the quality of metagenome-assembled genomes (MAGs). However, current binning methods struggle with identifying unknown species and managing imbalanced species distributions. He…
Fermented chrysanthemum stem as a source of natural phenolic compounds to alleviate tomato bacterial wilt disease Open
Natural antimicrobial compounds (NACs) in the plant stem are crucial for replacing conventional synthetic pesticides in the control of soil-borne diseases, and microbial fermentation can enhance their concentration and bioactivity. In this…
View article: Spatiotemporal changes in soil properties predict plant health at continental scale
Spatiotemporal changes in soil properties predict plant health at continental scale Open
Abiotic and biotic soil properties are strong predictors of plant yield globally 1–5 , but they become unreliable over large areas when plant health is threatened by pathogen 6–8 . Here we present a novel approach to predict plant health b…
View article: Substrate utilization and cross-feeding synergistically determine microbiome resistance to pathogen invasion
Substrate utilization and cross-feeding synergistically determine microbiome resistance to pathogen invasion Open
Understanding how microbiomes resist pathogen invasion remains a key challenge in natural ecosystems. Here, we combined genome-scale metabolic models with synthetic community experiments to unravel the mechanisms driving pathogen suppressi…
View article: Threat of Human Pathogens in Farmlands: A One Health Perspective
Threat of Human Pathogens in Farmlands: A One Health Perspective Open
A key aspect of “One Health” is to recognize that environmental health and human health are inseparable. In this interconnected network, farmland plays a crucial role, as it serves as a link connecting various ecosystems. However, the thre…
View article: Exploring the antibiotic resistance genes removal dynamics in chicken manure by composting
Exploring the antibiotic resistance genes removal dynamics in chicken manure by composting Open
Prolonged antibiotic usage in livestock farming leads to the accumulation of antibiotic resistance genes in animal manure. Composting has been shown as an effective way of removing antibiotic resistance from manures, but the specific mecha…
Bacterial imaging in tumour diagnosis Open
Some bacteria, such as Escherichia coli (E. coli) and Salmonella typhimurium (S. typhimurium), have an inherent ability to locate solid tumours, making them a versatile platform that can be combined with other tools to improve the tumour d…
Assessing intracellular and extracellular distribution of antibiotic resistance genes in the commercial organic fertilizers Open
Compost-based organic fertilizers often contain high levels of antibiotic resistance genes (ARGs) and mobile genetic elements (MGEs). Previous studies focused on quantification of total ARGs and MGEs. For a more accurate risk assessment of…
Protist predation selects for the soil resistome Open
A key aspect of “One Health” is to comprehend how antibiotic resistomes evolve naturally. In this issue, Nguyen and colleagues pioneered an in situ investigation on the impact of protist predations on the soil microbial community and its a…
Microbe-induced phenotypic variation leads to transgressive overyielding in clonal plant populations Open
Experiment Data
Positive regulation of the <span> <i>PhcB</i> </span> neighbouring regulator <span> <i>PrhX</i> </span> on expression of the type <span>III</span> secretion system and pathogenesis in <i>Ralstonia solanacearum</i> Open
Ralstonia solanacearum PhcB and PhcA control a quorum‐sensing (QS) system that globally regulates expression of about one third of all genes, including pathogenesis genes. The PhcB–PhcA QS system positively regulates the production of exop…
BP-tracer: Supplementary Data 2 Open
Supplementary Data 2 of BP-tracer Including: 1. BP-Tracer analysis results of simulated metagenomes 2. BP-Tracer analysis results of real metagenomes
BP-tracer: Supplementary Data 2 Open
Supplementary Data 2 of BP-tracer Including: 1. BP-Tracer analysis results of simulated metagenomes 2. BP-Tracer analysis results of real metagenomes
View article: DCiPatho: deep cross-fusion networks for genome scale identification of pathogens
DCiPatho: deep cross-fusion networks for genome scale identification of pathogens Open
Pathogen detection from biological and environmental samples is important for global disease control. Despite advances in pathogen detection using deep learning, current algorithms have limitations in processing long genomic sequences. Thr…
RsBarcode Open
Raw data, metafile and codes for barcode analyses
RsBarcode Open
Raw data, metafile and codes for barcode analyses
View article: MBPD: A multiple bacterial pathogen detection pipeline for One Health practices
MBPD: A multiple bacterial pathogen detection pipeline for One Health practices Open
Bacterial pathogens are one of the major threats to biosafety and environmental health, and advanced assessment is a prerequisite to combating bacterial pathogens. Currently, 16S rRNA gene sequencing is efficient in the open‐view detection…
Dataset: BacRefSeq and Mini-BacRefSeq Open
Please see README.md
Dataset: BacRefSeq and Mini-BacRefSeq Open
Please see README.md
Dataset: BacRefSeq and Mini-BacRefSeq Open
Please see README.md
Dataset: BacRefSeq and Mini-BacRefSeq Open
Please see README.md
Bacterial volatile organic compounds attenuate pathogen virulence via evolutionary trade-offs Open
Volatile organic compounds (VOCs) produced by soil bacteria have been shown to exert plant pathogen biocontrol potential owing to their strong antimicrobial activity. While the impact of VOCs on soil microbial ecology is well established, …