Gargi Bhattacharjee
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View article: New Amino Acids Naphthalene Scaffolds as Potent Antimicrobial Agents: <i>In Vitro</i> Assay and <i>In Silico</i> Molecular Docking Study
New Amino Acids Naphthalene Scaffolds as Potent Antimicrobial Agents: <i>In Vitro</i> Assay and <i>In Silico</i> Molecular Docking Study Open
The development of innovative antifungal medications to address the issues of indiscriminate antifungal use contributes to certain antifungal drug resistance. To tackle this issue, we have designed and synthesized novel amino acids naphtha…
View article: Nanotechnology and nucleic acid nanoparticles for treatment of metabolic disorders
Nanotechnology and nucleic acid nanoparticles for treatment of metabolic disorders Open
Metabolic disorders result from inborn and acquired dysfunction of organs and tissues that are responsible for producing energy in the body. These diseases are now among the most prevalent maladies in the world. Treatment often requires ad…
View article: Exploring the potential of microfluidics for next-generation drug delivery systems
Exploring the potential of microfluidics for next-generation drug delivery systems Open
The platform of microfluidics offers a precise control and manipulation over fluids at a small scale and therefore has gained much attention in recent times. This topic is currently applied to automation and high-throughput analysis in sev…
View article: Synthesis, biological evaluation and molecular docking study of novel amide-coupled naphthalene scaffolds as potent inhibitors of bacterial recombinase A
Synthesis, biological evaluation and molecular docking study of novel amide-coupled naphthalene scaffolds as potent inhibitors of bacterial recombinase A Open
The development of antimicrobials having a unique mode of action is essential to solve multi-drug resistance challenges. Herein, we have designed and synthesized novel amide-coupled naphthalene scaffolds (4a-l) by acid-amine coupling react…
View article: Phage engineering and phage‐assisted <scp>CRISPR‐Cas</scp> delivery to combat multidrug‐resistant pathogens
Phage engineering and phage‐assisted <span>CRISPR‐Cas</span> delivery to combat multidrug‐resistant pathogens Open
Antibiotic resistance ranks among the top threats to humanity. Due to the frequent use of antibiotics, society is facing a high prevalence of multidrug resistant pathogens, which have managed to evolve mechanisms that help them evade the l…
View article: Rebooting life: engineering non-natural nucleic acids, proteins and metabolites in microorganisms
Rebooting life: engineering non-natural nucleic acids, proteins and metabolites in microorganisms Open
The surging demand of value-added products has steered the transition of laboratory microbes to microbial cell factories (MCFs) for facilitating production of large quantities of important native and non-native biomolecules. This shift has…
View article: Vanillin containing 9H-fluoren sulfone scaffolds: Synthesis, biological evaluation and molecular docking study
Vanillin containing 9H-fluoren sulfone scaffolds: Synthesis, biological evaluation and molecular docking study Open
Vanillin containing 9H-fluoren sulfone scaffolds were prepared by coupling a sulfone amine with carboxylic acid group of amino acids in presence of peptide coupling reagent hexafluorophosphate benzotriazole tetramethyl uronium (HBTU). All …
View article: Exploring the Potential of Cell-Free Protein Synthesis for Extending the Abilities of Biological Systems
Exploring the Potential of Cell-Free Protein Synthesis for Extending the Abilities of Biological Systems Open
Cell-free protein synthesis (CFPS) system is a simple, rapid, and sensitive tool that is devoid of membrane-bound barriers, yet contains all the mandatory substrates, biomolecules, and machineries required for the synthesis of the desired …
View article: Corrigendum: Engineering Strategies in Microorganisms for the Enhanced Production of Squalene: Advances, Challenges and Opportunities
Corrigendum: Engineering Strategies in Microorganisms for the Enhanced Production of Squalene: Advances, Challenges and Opportunities Open
CORRECTION article Front. Bioeng. Biotechnol., 28 May 2019Sec. Synthetic Biology Volume 7 - 2019 | https://doi.org/10.3389/fbioe.2019.00114
View article: Engineering Strategies in Microorganisms for the Enhanced Production of Squalene: Advances, Challenges and Opportunities
Engineering Strategies in Microorganisms for the Enhanced Production of Squalene: Advances, Challenges and Opportunities Open
The triterpene squalene is a natural compound that has demonstrated an extraordinary diversity of uses in pharmaceutical, nutraceutical, and personal care industries. Emboldened by this range of uses, novel applications that can gain profi…
View article: Current progress in CRISPR‐based diagnostic platforms
Current progress in CRISPR‐based diagnostic platforms Open
The CRISPR‐Cas system is a key technology for genome editing and regulation in a wide range of organisms and cell types. Recently, CRISPR‐Cas–based diagnostic platform has shown idealistic properties for pathogen detection. Integrating the…
View article: Book Review: Quorum Sensing vs. Quorum Quenching: A Battle With No End in Sight
Book Review: Quorum Sensing vs. Quorum Quenching: A Battle With No End in Sight Open
This book has been written by well known scientists across globe. The editor is meticulously divided the book into seven parts comprising of 31 chapters that focus on the following aspects: (i) QS mediated processes, (ii) QS Systems in Mic…