Gary Brierly
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View article: Convergence of scaffold-guided bone regeneration principles and microvascular tissue transfer surgery
Convergence of scaffold-guided bone regeneration principles and microvascular tissue transfer surgery Open
A preclinical evaluation using a regenerative medicine methodology comprising an additively manufactured medical-grade ε-polycaprolactone β-tricalcium phosphate (mPCL-TCP) scaffold with a corticoperiosteal flap was undertaken in eight shee…
View article: Tumour Necrosis Factor Alpha (TNF-α) and Oral Squamous Cell Carcinoma
Tumour Necrosis Factor Alpha (TNF-α) and Oral Squamous Cell Carcinoma Open
Uncovering the inflammatory mechanisms underpinning initiation, progression, and promotion of oral squamous cell carcinoma (OSCC) development is fundamental to the rational pursuit of targeted therapeutics. Here we present a review of the …
View article: Ewing sarcoma of the facial soft tissues—a case report
Ewing sarcoma of the facial soft tissues—a case report Open
Ewing sarcoma (ES) is an uncommon malignancy of the maxillofacial region, primarily affecting the long bones and pelvis of the paediatric population. Within the head and neck, the facial skeleton is responsible for the majority of reported…
View article: Poly-ε-Caprolactone/Fibrin-Alginate Scaffold: A New Pro-Angiogenic Composite Biomaterial for the Treatment of Bone Defects
Poly-ε-Caprolactone/Fibrin-Alginate Scaffold: A New Pro-Angiogenic Composite Biomaterial for the Treatment of Bone Defects Open
We hypothesized that a composite of 3D porous melt-electrowritten poly-ɛ-caprolactone (PCL) coated throughout with a porous and slowly biodegradable fibrin/alginate (FA) matrix would accelerate bone repair due to its angiogenic potential. …
View article: Investigation of Sustained BMP Delivery in the Prevention of Medication‐Related Osteonecrosis of the Jaw (MRONJ) in a Rat Model
Investigation of Sustained BMP Delivery in the Prevention of Medication‐Related Osteonecrosis of the Jaw (MRONJ) in a Rat Model Open
Medication‐related osteonecrosis of the jaw (MRONJ) poses an ongoing challenge for clinicians and researchers. Currently, there is a lack of preventative measures available for at‐risk patients undergoing tooth extractions, especially thos…
View article: A Bench to Bedside Approach Towards the Prevention of Antiresorptive Drug-Related Osteonecrosis of the Jaw (ARONJ)
A Bench to Bedside Approach Towards the Prevention of Antiresorptive Drug-Related Osteonecrosis of the Jaw (ARONJ) Open
This project represents the development and application of tissue engineered constructs for the prevention of antiresorptive drug related osteonecrosis of the jaws (ARONJ). The project started from the laboratory and transitioned to a smal…
View article: Comparison of Different Decalcification Methods Using Rat Mandibles as a Model
Comparison of Different Decalcification Methods Using Rat Mandibles as a Model Open
Selection of decalcification agents is an essential consideration when processing mineralized tissues because the integrity and immunohistochemical characteristics of the tissues may be affected. Here, we report results obtained from the d…