Gary E. Gorbet
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Multi-Wavelength Analytical Ultracentrifugation of Biopolymer Mixtures and Interactions Open
Multi-wavelength analytical ultracentrifugation (MW-AUC) is a recent development made possible by new analytical ultracentrifuge optical systems. MW-AUC is suitable for a wide range of applications and biopolymer systems and is poised to b…
Multi-Wavelength Analytical Ultracentrifugation of Biopolymer Mixtures and Interactions Open
Multi-wavelength analytical ultracentrifugation (MW-AUC) is a recent development made possible by new analytical ultracentrifuge optical systems. MW-AUC is suitable for a wide range of applications and biopolymer systems and is poised to b…
View article: A Parametrically Constrained Optimization Method for Fitting Sedimentation Velocity Experiments
A Parametrically Constrained Optimization Method for Fitting Sedimentation Velocity Experiments Open
A method for fitting sedimentation velocity experiments using whole boundary Lamm equation solutions is presented. The method, termed parametrically constrained spectrum analysis (PCSA), provides an optimized approach for simultaneously mo…
Moving analytical ultracentrifugation software to a good manufacturing practices (GMP) environment Open
Recent advances in instrumentation have moved analytical ultracentrifugation (AUC) closer to a possible validation in a Good Manufacturing Practices (GMP) environment. In order for AUC to be validated for a GMP environment, stringent requi…