Gary Green
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View article: Quantile Function-Based Models for Neuroimaging Classification Using Wasserstein Regression
Quantile Function-Based Models for Neuroimaging Classification Using Wasserstein Regression Open
We propose a novel quantile function-based approach for neuroimaging classification using Wasserstein-Fréchet regression, specifically applied to the detection of mild traumatic brain injury (mTBI) based on the MEG and MRI data. Convention…
View article: Bayesian Inference General Procedures for A Single-subject Test study
Bayesian Inference General Procedures for A Single-subject Test study Open
Abnormality detection in identifying a single-subject which deviates from the majority of a control group dataset is a fundamental problem. Typically, the control group is characterised using standard Normal statistics, and the detection o…
View article: Detecting Mild Traumatic Brain Injury with MEG Scan Data: One-vs-K-Sample Tests
Detecting Mild Traumatic Brain Injury with MEG Scan Data: One-vs-K-Sample Tests Open
Magnetoencephalography (MEG) scanner has been shown to be more accurate than other medical devices in detecting mild traumatic brain injury (mTBI). However, MEG scan data in certain spectrum ranges can be skewed, multimodal and heterogeneo…
View article: Detecting mild traumatic brain injury with MEG scan data: One-vs-K-sample tests
Detecting mild traumatic brain injury with MEG scan data: One-vs-K-sample tests Open
Magnetoencephalography (MEG) scanner has been shown to be more accurate than other medical devices in detecting mild traumatic brain injury (mTBI). However, MEG scan data in certain spectrum ranges can be skewed, multimodal, and heterogene…
View article: Bayesian Inference General Procedures for A Single-subject Test Study
Bayesian Inference General Procedures for A Single-subject Test Study Open
Abnormality detection in identifying a single-subject which deviates from the majority of a control group dataset is a fundamental problem. Typically, the control group is characterised using standard Normal statistics, and the detection o…
View article: A METHOD OF CALIBRATION FOR ACOUSTIC EMISSION MEASUREMENTS
A METHOD OF CALIBRATION FOR ACOUSTIC EMISSION MEASUREMENTS Open
Studies of the intrinsic noise of an acoustic emission system, and studies of its response to a particular impulsive stimulus, have been shown to enable com parison to be made with similar data obtained with a system having different respo…
View article: Prevalence of Inflammatory Heart Disease Among Professional Athletes With Prior COVID-19 Infection Who Received Systematic Return-to-Play Cardiac Screening
Prevalence of Inflammatory Heart Disease Among Professional Athletes With Prior COVID-19 Infection Who Received Systematic Return-to-Play Cardiac Screening Open
This study provides large-scale data assessing the prevalence of relevant COVID-19-associated cardiac pathology with implementation of current RTP screening recommendations. While long-term follow-up is ongoing, few cases of inflammatory h…
View article: Molecular markers of telomere dysfunction and senescence are common findings in the usual interstitial pneumonia pattern of lung fibrosis
Molecular markers of telomere dysfunction and senescence are common findings in the usual interstitial pneumonia pattern of lung fibrosis Open
Aims Idiopathic pulmonary fibrosis (IPF) is a genetically mediated, age‐associated, progressive form of pulmonary fibrosis characterised pathologically by a usual interstitial pneumonia (UIP) pattern of fibrosis. The UIP pattern is also fo…
View article: Delineating single subject oscillatory brain networks with Spatio-Spectral Eigenmodes
Delineating single subject oscillatory brain networks with Spatio-Spectral Eigenmodes Open
The spatial and spectral structure of oscillatory networks in the brain provide a readout of the underlying neuronal function. Within and between subject variability in these networks can be highly informative but also poses a considerable…
View article: Airway Epithelial Telomere Dysfunction Drives Remodeling Similar to Chronic Lung Allograft Dysfunction
Airway Epithelial Telomere Dysfunction Drives Remodeling Similar to Chronic Lung Allograft Dysfunction Open
Telomere dysfunction is associated with multiple fibrotic lung processes, including chronic lung allograft dysfunction (CLAD)-the major limitation to long-term survival following lung transplantation. Although shorter donor telomere length…
View article: Public Health Responses to COVID-19 Outbreaks on Cruise Ships — Worldwide, February–March 2020
Public Health Responses to COVID-19 Outbreaks on Cruise Ships — Worldwide, February–March 2020 Open
An estimated 30 million passengers are transported on 272 cruise ships worldwide each year* (1). Cruise ships bring diverse populations into proximity for many days, facilitating transmission of respiratory illness (2). SARS-CoV-2, the vir…
View article: Peripheral blood leukocyte telomere length is associated with survival of sepsis patients
Peripheral blood leukocyte telomere length is associated with survival of sepsis patients Open
Shorter peripheral blood leukocyte (PBL) telomere length (TL) has been associated with poor outcomes in various chronic lung diseases. Whether PBL-TL is associated with survival from critical illness was tested in this study. We analysed d…
View article: Telomere Dysfunction Drives Chronic Lung Allograft Dysfunction Pathology
Telomere Dysfunction Drives Chronic Lung Allograft Dysfunction Pathology Open
Rationale Telomere dysfunction is associated with multiple fibrotic lung processes, including chronic lung allograft dysfunction (CLAD) which is a major limitation to long-term survival following lung transplantation. Although shorter dono…
View article: International consensus definitions of video signs of concussion in professional sports
International consensus definitions of video signs of concussion in professional sports Open
Background The use of video to assist professional sporting bodies with the diagnosis of sport-related concussion (SRC) has been well established; however, there has been little consistency across sporting codes with regards to which video…
View article: Tau pathology in early Alzheimer’s disease disrupts selective neurophysiological network dynamics
Tau pathology in early Alzheimer’s disease disrupts selective neurophysiological network dynamics Open
The role of aggregation of misfolded Tau protein in the pathogenesis of Alzheimer’s disease is the subject of rapid biomarker development and new therapeutic strategies to slow or prevent dementia. We tested the hypothesis that Tau patholo…
View article: Chronic Meningitis Investigated via Metagenomic Next-Generation Sequencing
Chronic Meningitis Investigated via Metagenomic Next-Generation Sequencing Open
Diverse microbial pathogens were identified by mNGS in the CSF of patients with diagnostically challenging subacute or chronic meningitis, including a case of subarachnoid neurocysticercosis that defied diagnosis for 1 year, the first repo…
View article: Metagenomics for chronic meningitis: clarifying interpretation and diagnosis
Metagenomics for chronic meningitis: clarifying interpretation and diagnosis Open
Importance Identifying infectious causes of subacute and chronic meningitis can be challenging. Enhanced, unbiased diagnostic approaches are needed. Objective To present a case series of patients with diagnostically challenging subacute an…
View article: A Simple Route to Strong Carbon‐13 NMR Signals Detectable for Several Minutes
A Simple Route to Strong Carbon‐13 NMR Signals Detectable for Several Minutes Open
Nuclear magnetic resonance (NMR) and magnetic resonance imaging (MRI) suffer from low sensitivity and limited nuclear spin memory lifetimes. Although hyperpolarization techniques increase sensitivity, there is also a desire to increase rel…
View article: Achieving High Levels of NMR‐Hyperpolarization in Aqueous Media With Minimal Catalyst Contamination Using SABRE
Achieving High Levels of NMR‐Hyperpolarization in Aqueous Media With Minimal Catalyst Contamination Using SABRE Open
Signal amplification by reversible exchange (SABRE) is shown to allow access to strongly enhanced 1 H NMR signals in a range of substrates in aqueous media. To achieve this outcome, phase‐transfer catalysis is exploited, which leads to les…
View article: Indecent exposure in chromosome 4q deletion syndrome
Indecent exposure in chromosome 4q deletion syndrome Open
Chromosome 4q deletion syndrome is a rare genetic disorder1 associated with a number of conditions such as cardiac, craniofacial, digital, and cognitive impairment, although the rarity of this condition causes difficulty in establishing ge…
View article: Harnessing polarisation transfer to indazole and imidazole through signal amplification by reversible exchange to improve their NMR detectability
Harnessing polarisation transfer to indazole and imidazole through signal amplification by reversible exchange to improve their NMR detectability Open
The signal amplification by reversible exchange (SABRE) approach has been used to hyperpolarise the substrates indazole and imidazole in the presence of the co‐ligand acetonitrile through the action of the precataysts [IrCl(COD)(IMes)] and…
View article: Short lung transplant donor telomere length is associated with decreased CLAD-free survival
Short lung transplant donor telomere length is associated with decreased CLAD-free survival Open
Telomere length (TL) decreases with cellular ageing and biological stressors. As advanced donor and recipient ages are risk factors for chronic lung allograft dysfunction (CLAD), we hypothesised that decreased age-adjusted donor TL would p…
View article: Delivering strong <sup>1</sup> H nuclear hyperpolarization levels and long magnetic lifetimes through signal amplification by reversible exchange
Delivering strong <sup>1</sup> H nuclear hyperpolarization levels and long magnetic lifetimes through signal amplification by reversible exchange Open
Significance The study of molecules and materials is of great significance to both science and human welfare. The noninvasive techniques of NMR and MRI reflect two of the most important methods to study them. However, both of these approac…
View article: The ASCENT (Allocation System Changes for Equity in Kidney Transplantation) Study: A Randomized Effectiveness-Implementation Study to Improve Kidney Transplant Waitlisting and Reduce Racial Disparity
The ASCENT (Allocation System Changes for Equity in Kidney Transplantation) Study: A Randomized Effectiveness-Implementation Study to Improve Kidney Transplant Waitlisting and Reduce Racial Disparity Open
The results from the ASCENT study will demonstrate the feasibility and effectiveness of a multicomponent intervention designed to increase access to the deceased-donor kidney waitlist and reduce racial disparities in waitlisting.
View article: SABRE hyperpolarisation of vitamin B3 as a function of pH
SABRE hyperpolarisation of vitamin B3 as a function of pH Open
NMR sensitivity enhanced through SABRE hyperpolarisation and pH manipulation enables the use of vitamin B3 as a pH probe.
View article: A Hyperpolarizable <sup>1</sup>H Magnetic Resonance Probe for Signal Detection 15 Minutes after Spin Polarization Storage
A Hyperpolarizable <sup>1</sup>H Magnetic Resonance Probe for Signal Detection 15 Minutes after Spin Polarization Storage Open
Nuclear magnetic resonance (NMR) and magnetic resonance imaging (MRI) are two extremely important techniques with applications ranging from molecular structure determination to human imaging. However, in many cases the applicability of NMR…