Gentle Sunder Shrestha
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View article: 192 Development of the proteogenomic antibody repertoire assay for anti-tumor antibody discovery
192 Development of the proteogenomic antibody repertoire assay for anti-tumor antibody discovery Open
View article: Correction: D-PRISM: a global survey-based study to assess diagnostic and treatment approaches in pneumonia managed in intensive care
Correction: D-PRISM: a global survey-based study to assess diagnostic and treatment approaches in pneumonia managed in intensive care Open
View article: Early management of adult severe traumatic brain injury: What researchers and clinicians must know
Early management of adult severe traumatic brain injury: What researchers and clinicians must know Open
View article: Evaluation of clinical research priorities in Asian intensive care units (ERA-ICU)
Evaluation of clinical research priorities in Asian intensive care units (ERA-ICU) Open
Background Practice and delivery of critical care in Asia varies according to healthcare structure, income setting, and cultural factors. Identifying research priorities specific to ICU patients and healthcare workers in Asia is needed to …
View article: Acute Endophthalmitis Following Intravitreal Anti-VEGF Injections: A Case Series
Acute Endophthalmitis Following Intravitreal Anti-VEGF Injections: A Case Series Open
View article: Palpation versus Ultrasound-Guided Dynamic Needle Tip Positioning Technique for Radial Artery Cannulation
Palpation versus Ultrasound-Guided Dynamic Needle Tip Positioning Technique for Radial Artery Cannulation Open
Introduction: Invasive blood pressure monitoring is the clinical reference during perioperative patient management. It is usually performed by cannulating the radial artery. Different clinical conditions make arterial cannulation difficult…
View article: Clinical Characteristics and Outcomes of Patients Managed with Percutaneous Dilatational Tracheostomy in the Intensive Care Unit: A Retrospective Observational Study
Clinical Characteristics and Outcomes of Patients Managed with Percutaneous Dilatational Tracheostomy in the Intensive Care Unit: A Retrospective Observational Study Open
Introduction: Percutaneous dilatational tracheostomy has emerged as a preferred minimally invasive alternative to surgical tracheostomy for critically ill patients requiring prolonged mechanical ventilation, though comprehensive data from …
View article: Bridging Breath and Survival: A Retrospective Analysis of Percutaneous Dilatational Tracheostomy in Critically Ill Patients
Bridging Breath and Survival: A Retrospective Analysis of Percutaneous Dilatational Tracheostomy in Critically Ill Patients Open
INTRODUCTION: Percutaneous Dilatational Tracheostomy (PDT) has gained widespread acceptance among critically ill patients requiring prolonged mechanical ventilation(MV) as a minimally invasive alternative to traditional surgical tracheosto…
View article: The Curing Coma campaign in Asia-Oceania
The Curing Coma campaign in Asia-Oceania Open
View article: A Seven-Year Audit of Intensive Care Unit Admissions and Outcome in a Tertiary Care Hospital in Nepal
A Seven-Year Audit of Intensive Care Unit Admissions and Outcome in a Tertiary Care Hospital in Nepal Open
Introduction An audit is used to assess if a particular aspect of health care is in accordance with the standard practice and aims to achieve improvement in quality for the benefit of the patient. The current study is a retrospective descr…
View article: Author Response: Appropriately Designed Studies are Needed before Thiamine and Vitamin C Plus Hydrocortisone are Judged Nonbeneficial in Septic Shock
Author Response: Appropriately Designed Studies are Needed before Thiamine and Vitamin C Plus Hydrocortisone are Judged Nonbeneficial in Septic Shock Open
How to cite this article: Sharma S, Paneru HR, Shrestha GS, Shrestha PS, Acharya SP. Author Response: Appropriately Designed Studies are Needed before Thiamine and Vitamin C Plus Hydrocortisone are Judged Nonbeneficial in Septic Sho…
View article: The Brussels consensus for non-invasive ICP monitoring when invasive systems are not available in the care of TBI patients (the B-ICONIC consensus, recommendations, and management algorithm)
The Brussels consensus for non-invasive ICP monitoring when invasive systems are not available in the care of TBI patients (the B-ICONIC consensus, recommendations, and management algorithm) Open
View article: VENTIlatory strategies for patients with severe traumatic brain injury in the LOw- and Middle-Income CountrieS. The VENTILOMICS survey
VENTIlatory strategies for patients with severe traumatic brain injury in the LOw- and Middle-Income CountrieS. The VENTILOMICS survey Open
The findings suggest a consistent approach to lung-protective ventilation across low-and middle-income countries, with notable variations influenced by local resources and economic status. This study highlights the necessity for tailored r…
View article: Management of adult sepsis in resource-limited settings: global expert consensus statements using a Delphi method
Management of adult sepsis in resource-limited settings: global expert consensus statements using a Delphi method Open
View article: VENTIlatory strategies for patients with severe traumatic brain injury in the LOw- and Middle-Income CountrieS – The VENTILOMICS survey
VENTIlatory strategies for patients with severe traumatic brain injury in the LOw- and Middle-Income CountrieS – The VENTILOMICS survey Open
Introduction - Traumatic brain injury (TBI) poses a significant global health challenge, particularly in low- and middle-income countries (LMICs), where the disease burden is exacerbated by limited resources and preventative measures. This…
View article: Evaluation of the Effects of a Combination of Vitamin C, Thiamine and Hydrocortisone vs Hydrocortisone Alone on ICU Outcome in Patients with Septic Shock: A Randomized Controlled Trial
Evaluation of the Effects of a Combination of Vitamin C, Thiamine and Hydrocortisone vs Hydrocortisone Alone on ICU Outcome in Patients with Septic Shock: A Randomized Controlled Trial Open
Sharma S, Paneru HR, Shrestha GS, Shrestha PS, Acharya SP. Evaluation of the Effects of a Combination of Vitamin C, Thiamine and Hydrocortisone vs Hydrocortisone Alone on ICU Outcome in Patients with Septic Shock: A Randomized Controlled T…
View article: International cross-sectional survey on current and updated definitions of intra-abdominal hypertension and abdominal compartment syndrome
International cross-sectional survey on current and updated definitions of intra-abdominal hypertension and abdominal compartment syndrome Open
View article: D-PRISM: a global survey-based study to assess diagnostic and treatment approaches in pneumonia managed in intensive care
D-PRISM: a global survey-based study to assess diagnostic and treatment approaches in pneumonia managed in intensive care Open
Background Pneumonia remains a significant global health concern, particularly among those requiring admission to the intensive care unit (ICU). Despite the availability of international guidelines, there remains heterogeneity in clinical …
View article: 7024 Papillary Thyroid cancer in rare cystic form
7024 Papillary Thyroid cancer in rare cystic form Open
Disclosure: G. Shrestha: None. F. Qureshi: None. K. Yadav: None. S. Shrestha: None. S. Sapkota: None. M. Yadav: None. Background: Thyroid nodules are often asymptomatic and usually discovered incidentally. Thyroid cancer is found in about …
View article: Tracheal intubation in critically ill adults with a physiologically difficult airway. An international Delphi study
Tracheal intubation in critically ill adults with a physiologically difficult airway. An international Delphi study Open
View article: Management of Adult Sepsis in Resource-Limited Settings: Global Expert Consensus Statements Using a Delphi Method
Management of Adult Sepsis in Resource-Limited Settings: Global Expert Consensus Statements Using a Delphi Method Open
Purpose To generate consensus and provide expert clinical practice statements for the management of adult sepsis in resource-limited settings. Methods An international multidisciplinary Steering Committee with expertise in sepsis managemen…
View article: Impact of country income level on outcomes in acute brain injured patients requiring invasive mechanical ventilation: a secondary analysis of the ENIO study
Impact of country income level on outcomes in acute brain injured patients requiring invasive mechanical ventilation: a secondary analysis of the ENIO study Open
BACKGROUND/OBJECTIVES: Invasive mechanical ventilation (IMV) can present complex challenges for patients with acute brain injury (ABI) in middle income countries (MICs). We characterized the impact of country income level on weaning strate…
View article: Correction: Use of ketamine in super refractory status epilepticus: a systematic review
Correction: Use of ketamine in super refractory status epilepticus: a systematic review Open
View article: Use of ketamine in Super Refractory Status Epilepticus: a systematic review
Use of ketamine in Super Refractory Status Epilepticus: a systematic review Open
View article: Perception and Willingness Regarding Organ Transplantation/donation among Medical Students of Maharajgunj Medical Campus: A Cross-sectional Study
Perception and Willingness Regarding Organ Transplantation/donation among Medical Students of Maharajgunj Medical Campus: A Cross-sectional Study Open
Background: Organ transplant is the procedure of replacing a failing or damaged organ with a functioning one. Positive attitude and awareness about donation are a must for donor organs to be available. This study explored the level of know…
View article: Antimicrobial therapeutic drug monitoring in critically ill adult patients – An international perspective on access, utilisation, and barriers
Antimicrobial therapeutic drug monitoring in critically ill adult patients – An international perspective on access, utilisation, and barriers Open
This global survey indicated that consistent TDM usage is hindered by assay access in some sites and the timeliness of assay results in others. Addressing barriers to TDM, particularly in low-income countries, should be a priority to ensur…
View article: D-PRISM, a global study of diagnostic approaches in severe pneumonia.
D-PRISM, a global study of diagnostic approaches in severe pneumonia. Open
Purpose Pneumonia remains a significant global health concern, particularly among those requiring admission to the intensive care unit (ICU). Despite the availability of international guidelines there remains heterogeneity in clinical mana…
View article: Admission time and outcomes of patients admitted to intensive care unit in a tertiary hospital in Nepal: an observational study
Admission time and outcomes of patients admitted to intensive care unit in a tertiary hospital in Nepal: an observational study Open
Background and aims: Time of admission to the intensive care unit may have a significant impact on the outcome. However, there is scarcity of published literature regarding admission hours and outcomes from low-income and middle-income cou…
View article: Using Optic Nerve Sheath Diameter for Intracranial Pressure (ICP) Monitoring in Traumatic Brain Injury: A Scoping Review
Using Optic Nerve Sheath Diameter for Intracranial Pressure (ICP) Monitoring in Traumatic Brain Injury: A Scoping Review Open
View article: Consensus Statement on Standards for Neurocritical Care Units in Low-Income and Middle-Income Countries (LMICs).
Consensus Statement on Standards for Neurocritical Care Units in Low-Income and Middle-Income Countries (LMICs). Open
The disease burden of severe neurological and neurosurgical illnesses in low-income and middle-income countries (LMICs) is high. Management of these patients by a dedicated neurocritical care team can improve outcome. Globally, there is si…