Lin Han
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View article: Electronic‐Structure‐Guided Screening of Piperazine Derivatives: Achieving Efficient CO <sub>2</sub> Capture with High Cyclic Capacity and Low Energy Consumption
Electronic‐Structure‐Guided Screening of Piperazine Derivatives: Achieving Efficient CO <sub>2</sub> Capture with High Cyclic Capacity and Low Energy Consumption Open
Piperazine (PZ) is a promising alternative to monoethanolamine (MEA) for CO 2 capture, yet its low desorption efficiency restricts practical implementation. Here, a density functional theory (DFT)‐driven framework is developed to identify …
View article: Stereo‐cell: A planar DNA nanoball‐array route to ultrahigh‐throughput, imaging‐integrated single‐cell profiling
Stereo‐cell: A planar DNA nanoball‐array route to ultrahigh‐throughput, imaging‐integrated single‐cell profiling Open
Single‐cell sequencing has been constrained by the trade‐off among throughput, capture bias, and compatibility with cells of unusual size or morphology. A recent innovative approach, Stereo‐cell, addresses these constraints by coupling hig…
View article: Continuously adjustable-pulse-width electro-optically Q-switched laser with Nd:YVO<sub>4</sub>/Nd:YAG dual crystals
Continuously adjustable-pulse-width electro-optically Q-switched laser with Nd:YVO<sub>4</sub>/Nd:YAG dual crystals Open
This paper reports an electro-optically Q-switched Nd:YVO 4 /Nd:YAG laser with continuously adjustable pulse width. The tunability of the pulse width is realized by adjusting the pump power on the two crystals. We establish a dual-crystal …
View article: Study on Influence of Evaporation Tube Flow Distribution on Combustion Characteristics of Micro Combustion Chamber
Study on Influence of Evaporation Tube Flow Distribution on Combustion Characteristics of Micro Combustion Chamber Open
The combustion chamber is a critical component of turbojet engines, and airflow distribution plays an essential role in ensuring flame stability and optimizing combustion efficiency. This study investigates a miniature annular combustion c…
View article: High‐throughput exosomes analysis for ovarian cancer screening based on a double‐positive surface marker detection biochip
High‐throughput exosomes analysis for ovarian cancer screening based on a double‐positive surface marker detection biochip Open
Exosomes have the potential to be a noninvasive tumor biomarker for cancer diagnosis and classification. However, high‐efficiency capture and analysis of exosomes in complex biological samples remain challenging. Here, we propose a high‐th…
View article: Occurrence of White Flesh Color and Refreshing Flavor Following <i>Phytoene Synthase 2A</i> Gene Variation in Loquat Fruit
Occurrence of White Flesh Color and Refreshing Flavor Following <i>Phytoene Synthase 2A</i> Gene Variation in Loquat Fruit Open
Loquat fruits from the apple tribe of Rosaceae ripen from late spring to early summer, when most fresh fruits are out of season. Compared with the orange-fleshed varieties, the white-fleshed varieties are usually preferentially chosen by c…
View article: CD19 chimeric antigen receptor‐T cell therapy in murine immune thrombocytopenia
CD19 chimeric antigen receptor‐T cell therapy in murine immune thrombocytopenia Open
Summary Immune thrombocytopenia (ITP) is an autoimmune disorder characterized by antiplatelet autoantibodies, with many patients refractory or relapsing on conventional treatments. GPIbα, an important autoantigen in ITP, is notably linked …
View article: The modified heart team protocol facilitated the revascularization decision-making quality in complex coronary artery disease
The modified heart team protocol facilitated the revascularization decision-making quality in complex coronary artery disease Open
OBJECTIVES A lack of standardization in heart team implementation potentially leads to suboptimal decision-making quality, and we previously established a modified heart team protocol to improve the decision-making quality. The present tri…
View article: Advancing Digital Transformation in Material Science: The Role of Workflows Within the MaterialDigital Initiative
Advancing Digital Transformation in Material Science: The Role of Workflows Within the MaterialDigital Initiative Open
The MaterialDigital initiative represents a major driver toward the digitalization of material science. Next to providing a prototypical infrastructure required for building a shared data space and working on semantic interoperability of d…
View article: Flexible Graphene Field-Effect Transistors and Their Application in Flexible Biomedical Sensing
Flexible Graphene Field-Effect Transistors and Their Application in Flexible Biomedical Sensing Open
Flexible electronics are transforming our lives by making daily activities more convenient. Central to this innovation are field-effect transistors (FETs), valued for their efficient signal processing, nanoscale fabrication, low-power cons…
View article: Double-Heading Produces Larger Fruit via Inhibiting EjFWLs Expression and Promoting Cell Division at the Early Stage of Loquat Fruit Development
Double-Heading Produces Larger Fruit via Inhibiting EjFWLs Expression and Promoting Cell Division at the Early Stage of Loquat Fruit Development Open
Loquat is an evergreen fruit crop which blooms from autumn–winter, and supports human beings with juicy fruit from late spring to early summer. However, the most traditional cultivars of this crop produce small fruit and bear a much lower …
View article: Direct air capture of CO2 by amine-impregnated resin: The effect of resin pore structure and humid conditions
Direct air capture of CO2 by amine-impregnated resin: The effect of resin pore structure and humid conditions Open
Direct air capture (DAC) by solid amine adsorbents is a promising technology to curb the increasing atmospheric CO2 level. Despite extensive efforts, there are still limited improvements for this type of materials in their CO2 uptake and a…
View article: Microfluidic Biochips for Single‐Cell Isolation and Single‐Cell Analysis of Multiomics and Exosomes
Microfluidic Biochips for Single‐Cell Isolation and Single‐Cell Analysis of Multiomics and Exosomes Open
Single‐cell multiomic and exosome analyses are potent tools in various fields, such as cancer research, immunology, neuroscience, microbiology, and drug development. They facilitate the in‐depth exploration of biological systems, providing…
View article: An rGO-doped laser induced graphene electrochemical biosensor for highly sensitive exosome detection
An rGO-doped laser induced graphene electrochemical biosensor for highly sensitive exosome detection Open
An electrochemical biosensing chip using rGO-modified LIG was developed to detect exosomes for breast cancer diagnostics.
View article: Immune function assessing of TIM3/CD28‐modified CD19 CAR‐T cells and general CD19 CAR‐T cells through a high‐throughput single‐cell microarray platform
Immune function assessing of TIM3/CD28‐modified CD19 CAR‐T cells and general CD19 CAR‐T cells through a high‐throughput single‐cell microarray platform Open
Chimeric antigen receptor (CAR) T cells are widely used to treat hematological tumors due to their powerful ability to target and kill cancer cells, of which accurate function evaluation at the single‐cell level is crucial to ensuring the …
View article: Comprehensive metabolome and transcriptome analyses demonstrate divergent anthocyanin and carotenoid accumulation in fruits of wild and cultivated loquats
Comprehensive metabolome and transcriptome analyses demonstrate divergent anthocyanin and carotenoid accumulation in fruits of wild and cultivated loquats Open
Eriobotrya is an evergreen fruit tree native to South-West China and adjacent countries. There are more than 26 loquat species known in this genus, while E. japonica is the only species yet domesticated to produce fresh fruits from late sp…
View article: Inhibitory effect of zinc oxide nanorod arrays on breast cancer cells profiled through real‐time cytokines screening by a single‐cell microfluidic platform (3/2023)
Inhibitory effect of zinc oxide nanorod arrays on breast cancer cells profiled through real‐time cytokines screening by a single‐cell microfluidic platform (3/2023) Open
In this article number 10.1002/bmm2.12040, Ping Li, Chao Wang and their co-workers systematically studied the inhibitory effects of zinc oxide nanorods (ZnO NRs) on breast cancer cells. They found that the ZnO NRs inhibited the migration a…
View article: Inhibitory effect of zinc oxide nanorod arrays on breast cancer cells profiled through real‐time cytokines screening by a single‐cell microfluidic platform
Inhibitory effect of zinc oxide nanorod arrays on breast cancer cells profiled through real‐time cytokines screening by a single‐cell microfluidic platform Open
Zinc oxide nanorods have been extensively studied for the specific killing of breast cancer (BC) cells, and their killing mechanism and anticancer effects have been initially demonstrated. However, systematic studies at the single‐cell lev…
View article: Front Cover: Hydrogenated silicene nanosheet functionalized scaffold enables immuno‐bone remodeling (EXP2 4/2023)
Front Cover: Hydrogenated silicene nanosheet functionalized scaffold enables immuno‐bone remodeling (EXP2 4/2023) Open
Bone immunity plays a vital role in bone repair involving implanted materials. Upon implantation of biomaterials into bone defect sites, a series of immune reactions are promptly triggered. Positive bone immunity helps regulate the inflamm…
View article: Highly Stable InSe-FET Biosensor for Ultra-Sensitive Detection of Breast Cancer Biomarker CA125
Highly Stable InSe-FET Biosensor for Ultra-Sensitive Detection of Breast Cancer Biomarker CA125 Open
Two-dimensional materials-based field-effect transistors (FETs) are promising biosensors because of their outstanding electrical properties, tunable band gap, high specific surface area, label-free detection, and potential miniaturization …
View article: Recent methods of droplet microfluidics and their applications in spheroids and organoids
Recent methods of droplet microfluidics and their applications in spheroids and organoids Open
This review provides an overview of recent advances in droplet microfluidics for the formation and manipulation of spheroids and organoids, as well as their downstream applications in high-throughput screening and tissue engineering.
View article: Mesoporous Silica Promotes Osteogenesis of Human Adipose-Derived Stem Cells Identified by a High-Throughput Microfluidic Chip Assay
Mesoporous Silica Promotes Osteogenesis of Human Adipose-Derived Stem Cells Identified by a High-Throughput Microfluidic Chip Assay Open
Silicon-derived biomaterials are conducive to regulating the fate of osteo-related stem cells, while their effects on the osteogenic differentiation of human adipose-derived stem cells (hADSCs) remain inconclusive. Mesoporous silica (mSiO2…
View article: Multiple Biomarker Simultaneous Detection in Serum via a Nanomaterial-Functionalized Biosensor for Ovarian Tumor/Cancer Diagnosis
Multiple Biomarker Simultaneous Detection in Serum via a Nanomaterial-Functionalized Biosensor for Ovarian Tumor/Cancer Diagnosis Open
Ovarian tumors/cancers are threatening women’s health worldwide, which demands high-performance detection methods and accurate strategies to effectively detect, diagnose and treat them. Here, we report a nanographene oxide particle-functio…
View article: Insights on the possibility of SARS-CoV-2 transmission through the eyes
Insights on the possibility of SARS-CoV-2 transmission through the eyes Open
A novel coronavirus, named severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2 or 2019-nCOV), causing coronavirus disease 2019 (COVID-19), has rapidly spread to most countries and regions worldwide since it broke out at the end of …
View article: A Sensitive and Portable Double-Layer Microfluidic Biochip for Harmful Algae Detection
A Sensitive and Portable Double-Layer Microfluidic Biochip for Harmful Algae Detection Open
Harmful algal blooms (HABs) are common disastrous ecological anomalies in coastal waters. An effective algae monitoring approach is important for natural disaster warning and environmental governance. However, conducting rapid and sensitiv…