Geffen Lass
YOU?
Author Swipe
View article: GABA Signaling in the Posterodorsal Medial Amygdala Mediates Stress-induced Suppression of LH Pulsatility in Female Mice
GABA Signaling in the Posterodorsal Medial Amygdala Mediates Stress-induced Suppression of LH Pulsatility in Female Mice Open
Psychological stress is linked to infertility by suppressing the hypothalamic GnRH pulse generator. The posterodorsal subnucleus of the medial amygdala (MePD) is an upstream regulator of GnRH pulse generator activity and displays increased…
View article: OR17-2 GABAergic Signalling in the Posterodorsal Medial Amygdala Mediates Psychological Stress-induced Suppression of the GnRH Pulse Generator in Female Mice
OR17-2 GABAergic Signalling in the Posterodorsal Medial Amygdala Mediates Psychological Stress-induced Suppression of the GnRH Pulse Generator in Female Mice Open
Psychological stress is linked to infertility and reproductive dysfunction by suppressing the hypothalamic gonadotropin-releasing hormone (GnRH) pulse generator and pulsatile luteinising hormone (LH) secretion. The posterodorsal subnucleus…
View article: <scp>GnRH</scp> pulse generator frequency is modulated by kisspeptin and <scp>GABA</scp> ‐glutamate interactions in the posterodorsal medial amygdala in female mice
<span>GnRH</span> pulse generator frequency is modulated by kisspeptin and <span>GABA</span> ‐glutamate interactions in the posterodorsal medial amygdala in female mice Open
Kisspeptin neurons in the arcuate nucleus of the hypothalamus generate gonadotrophin‐releasing hormone (GnRH) pulses, and act as critical initiators of functional gonadotrophin secretion and reproductive competency. However, kisspeptin in …
View article: Role of Posterodorsal Medial Amygdala Urocortin-3 in Pubertal Timing in Female Mice
Role of Posterodorsal Medial Amygdala Urocortin-3 in Pubertal Timing in Female Mice Open
Post-traumatic stress disorder impedes pubertal development and disrupts pulsatile LH secretion in humans and rodents. The posterodorsal sub-nucleus of the medial amygdala (MePD) is an upstream modulator of the hypothalamic gonadotropin-re…
View article: Role of posterodorsal medial amygdala urocortin-3 in pubertal timing in female mice
Role of posterodorsal medial amygdala urocortin-3 in pubertal timing in female mice Open
Post-traumatic stress disorder impedes pubertal development and disrupts pulsatile LH secretion in humans and rodents. The posterodorsal sub-nucleus of the medial amygdala (MePD) is an upstream modulator of the hypothalamic gonadotropin-re…
View article: GnRH pulse generator frequency is modulated by kisspeptin and GABA-glutamate interactions in the posterodorsal medial amygdala in female mice
GnRH pulse generator frequency is modulated by kisspeptin and GABA-glutamate interactions in the posterodorsal medial amygdala in female mice Open
Kisspeptin neurons in the arcuate nucleus of the hypothalamus generate GnRH pulses, and act as critical initiators of functional gonadotrophin secretion, and reproductive competency. However, kisspeptin in other brain regions, most notably…
View article: Optogenetic Activation of Arcuate Kisspeptin Neurons Generates a Luteinizing Hormone Surge-Like Secretion in an Estradiol-Dependent Manner
Optogenetic Activation of Arcuate Kisspeptin Neurons Generates a Luteinizing Hormone Surge-Like Secretion in an Estradiol-Dependent Manner Open
Traditionally, the anteroventral periventricular (AVPV) nucleus has been the brain area associated with luteinizing hormone (LH) surge secretion in rodents. However, the role of the other population of hypothalamic kisspeptin neurons, in t…
View article: Is there a correlation between total fertility rate, utilization of assisted reproduction technology, and national wealth in Europe?
Is there a correlation between total fertility rate, utilization of assisted reproduction technology, and national wealth in Europe? Open
There is a strong correlation across Europe between GDP and utilization of ART. This correlation does not exist within the developed economies. In Europe the utilization of ART treatment is dependent on national wealth and not on the TFR i…
View article: Dynorphin and GABAA Receptor Signaling Contribute to Progesterone’s Inhibition of the LH Surge in Female Mice
Dynorphin and GABAA Receptor Signaling Contribute to Progesterone’s Inhibition of the LH Surge in Female Mice Open
Progesterone can block estrogen-induced luteinising hormone (LH) surge secretion and can be used clinically to prevent premature LH surges. The blocking effect of progesterone on the LH surge is mediated through its receptor in the anterov…
View article: Optogenetic stimulation of kisspeptin neurones within the posterodorsal medial amygdala increases luteinising hormone pulse frequency in female mice
Optogenetic stimulation of kisspeptin neurones within the posterodorsal medial amygdala increases luteinising hormone pulse frequency in female mice Open
Kisspeptin within the arcuate nucleus of the hypothalamus is a critical neuropeptide in the regulation of reproduction. Together with neurokinin B and dynorphin A, arcuate kisspeptin provides the oscillatory activity that drives the pulsat…
View article: The Origin of GnRH Pulse Generation: An Integrative Mathematical-Experimental Approach
The Origin of GnRH Pulse Generation: An Integrative Mathematical-Experimental Approach Open
Fertility critically depends on the gonadotropin-releasing hormone (GnRH) pulse generator, a neural construct comprised of hypothalamic neurons coexpressing kisspeptin, neurokoinin-B and dynorphin. Here, using mathematical modeling and in …
View article: Correlation between gross domestic product, utilization of in vitro fertilization, and pregnancy success rate across the world
Correlation between gross domestic product, utilization of in vitro fertilization, and pregnancy success rate across the world Open
Background: IVF is now a wide spread procedure globally, and currently 65 countries report annually all or part of their IVF/ICSI cycles, from which the International Committee Monitoring progress in Assisted Reproduction Technology (ICMAR…
View article: Optogenetic stimulation of kisspeptin neurones within the posterodorsal medial amygdala increases LH pulse frequency in female mice
Optogenetic stimulation of kisspeptin neurones within the posterodorsal medial amygdala increases LH pulse frequency in female mice Open
Kisspeptin within the arcuate nucleus of the hypothalamus is a critical neuropeptide in the regulation of reproduction. Together with neurokinin and dynorphin A, arcuate kisspeptin provides the oscillatory activity that drives the pulsatil…
View article: Maternal High Triglyceride Levels During Early Pregnancy and Risk of Preterm Delivery: A Retrospective Cohort Study
Maternal High Triglyceride Levels During Early Pregnancy and Risk of Preterm Delivery: A Retrospective Cohort Study Open
Context Maternal obesity increases the risk of preterm delivery. Obesity is known to be associated with altered lipid metabolism. Objective To investigate the associations between high maternal triglyceride (mTG) levels during early pregna…
View article: Kisspeptin neurones in the posterodorsal medial amygdala modulate sexual partner preference and anxiety in male mice
Kisspeptin neurones in the posterodorsal medial amygdala modulate sexual partner preference and anxiety in male mice Open
The posterodorsal medial amygdala (MePD) is a neural site in the limbic brain involved in regulating emotional and sexual behaviours. There is, however, limited information available on the specific neuronal cell type in the MePD functiona…
View article: Mathematical modelling elucidates core mechanisms underpinning GnRH pulse generation
Mathematical modelling elucidates core mechanisms underpinning GnRH pulse generation Open
Summary Fertility critically depends on the gonadotropin-releasing hormone (GnRH) pulse generator, a neural construct comprised of hypothalamic neurons co-expressing kisspeptin, neurokoinin-B and dynorphin that drives the pulsatile release…