Gejin Lu
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View article: Anti-inflammatory, antioxidant and anti-virulence roles of atractylodin in attenuating Listeria monocytogenes infection
Anti-inflammatory, antioxidant and anti-virulence roles of atractylodin in attenuating Listeria monocytogenes infection Open
Background Listeria monocytogenes ( L. monocytogenes ), as a pandemic foodborne pathogen, severely threatens food security and public health care worldwide, which evolves multiple bacterial virulence factors (such as listeriolysin O, LLO) …
View article: Gut Microbiota Structure of Dead Migratory Birds in Dali Nouer Lake, Chifeng City, China, based on Bacterial 16S rRNA Amplicon Sequencing
Gut Microbiota Structure of Dead Migratory Birds in Dali Nouer Lake, Chifeng City, China, based on Bacterial 16S rRNA Amplicon Sequencing Open
21 In August 2018, hundreds of migratory birds died in the area of Dali Nouer Lake, Chifeng City, 22 China. We collected the remains of dead birds along with water and aquatic plants from the birds’ 23 environment. The bacterial communitie…
View article: Pan-Genome Analysis of Vibrio cholerae and Vibrio metschnikovii Strains Isolated From Migratory Birds at Dali Nouer Lake in Chifeng, China
Pan-Genome Analysis of Vibrio cholerae and Vibrio metschnikovii Strains Isolated From Migratory Birds at Dali Nouer Lake in Chifeng, China Open
Migratory birds are recently recognized as Vibrio disease vectors, but may be widespread transporters of Vibrio strains. We isolated Vibrio cholerae (V. cholerae) and Vibrio metschnikovii (V. metschnikovii) strains from migratory bird epid…
View article: A potential bio‐control agent from baical skullcap root against listeriosis via the inhibition of sortase A and listeriolysin O
A potential bio‐control agent from baical skullcap root against listeriosis via the inhibition of sortase A and listeriolysin O Open
Listeria monocytogenes (LM) is a classical model intracellular pathogen and the leading cause of listeriosis, which has long been a global public health issue. The successful infection of LM is related to a series of virulence factors, suc…
View article: Chalcone Attenuates Staphylococcus aureus Virulence by Targeting Sortase A and Alpha-Hemolysin
Chalcone Attenuates Staphylococcus aureus Virulence by Targeting Sortase A and Alpha-Hemolysin Open
Staphylococcus aureus (S.aureus) resistance, considered a dilemma for the clinical treatment of this bacterial infection, is becoming increasingly intractable. Novel anti-virulence strategies will undoubtedly provide a path f…
View article: Curcumin Promotes the Clearance of Listeria monocytogenes both In Vitro and In Vivo by Reducing Listeriolysin O Oligomers
Curcumin Promotes the Clearance of Listeria monocytogenes both In Vitro and In Vivo by Reducing Listeriolysin O Oligomers Open
The pore-forming toxin listeriolysin O (LLO), an essential virulence factor that is secreted by Listeria monocytogenes (L. monocytogenes), is responsible for bacterial breaching at the phagosomal membranes and subsequent rele…
View article: Morin Attenuates Streptococcus suis Pathogenicity in Mice by Neutralizing Suilysin Activity
Morin Attenuates Streptococcus suis Pathogenicity in Mice by Neutralizing Suilysin Activity Open
Streptococcus suis, a Gram-positive pathogen, is widely recognized as an important agent of swine infection, and it is also known to cause a variety of zoonoses, such as meningitis, polyarthritis and pneumonia. Suilysin (SLY), an ex…
View article: Phloretin Attenuates Listeria monocytogenes Virulence Both In vitro and In vivo by Simultaneously Targeting Listeriolysin O and Sortase A
Phloretin Attenuates Listeria monocytogenes Virulence Both In vitro and In vivo by Simultaneously Targeting Listeriolysin O and Sortase A Open
The critical roles of sortase A (SrtA) and listeriolysin O (LLO) in Listeria monocytogenes pathogenicity render these two virulence factors as ideal targets for the development of anti-virulence agents against L. monocytogenes infection. A…