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View article: Modulating Effect of Carbohydrate Antigen 125 on the Prognostic Value of High-Sensitivity C-Reactive Protein in Heart Failure
Modulating Effect of Carbohydrate Antigen 125 on the Prognostic Value of High-Sensitivity C-Reactive Protein in Heart Failure Open
Inflammation and congestion are key pathophysiological processes in heart failure (HF). Our aim was to evaluate the potential modulatory effect of carbohydrate antigen 125 (CA125) on inflammation, assessed by high-sensitivity C-reactive pr…
View article: Predictors of long-term survival in patients with a first episode of acute heart failure
Predictors of long-term survival in patients with a first episode of acute heart failure Open
Survival after a first AHF episode is poor, with age, New York Heart Association class, kidney function, coronary artery disease, diabetes, and sex being key predictors of long-term mortality.
View article: Baseline serum ferritin predicts myocardial iron uptake following intravenous iron therapy – a hypothesis‐generating study
Baseline serum ferritin predicts myocardial iron uptake following intravenous iron therapy – a hypothesis‐generating study Open
Aims Many patients with heart failure (HF) are iron‐deficient. Intravenous (IV) iron therapy improves symptoms and reduces hospitalizations for HF. Several mechanisms have been proposed, including myocardial iron repletion. However, it is …
View article: NT-proBNP to guide risk stratification after cardiac rehabilitation in patients with ST-segment elevation myocardial infarction
NT-proBNP to guide risk stratification after cardiac rehabilitation in patients with ST-segment elevation myocardial infarction Open
Even after comprehensive adjustment, NT-proBNP emerges as a potent, accessible and inexpensive tool for risk stratification of STEMI patients after completion of rehabilitation programs.
View article: Rotational Atherectomy, Lithotripsy, or Laser for Calcified Coronary Stenosis
Rotational Atherectomy, Lithotripsy, or Laser for Calcified Coronary Stenosis Open
In the first randomized trial comparing RA, IVL, and ELCA for the treatment of patients with calcified coronary lesions, IVL was noninferior to RA in terms of stent expansion. ELCA did not reach this noninferiority margin compared with RA.…
View article: The modulating effect of circulating carbohydrate antigen 125 on ST2 and long-term recurrent morbidity burden
The modulating effect of circulating carbohydrate antigen 125 on ST2 and long-term recurrent morbidity burden Open
View article: Baseline ferritin predicts myocardial iron uptake following intravenous iron therapy- a hypothesis generating study
Baseline ferritin predicts myocardial iron uptake following intravenous iron therapy- a hypothesis generating study Open
Aims Iron deficiency (ID) is a common co-morbidity in heart failure (HF). Intravenous iron therapy improves outcomes. Several mechanisms have been proposed, including myocardial iron repletion. However, it is unknown if clinical iron marke…
View article: Changes in Antigen Carbohydrate 125 in Patients Receiving Dapagliflozin following an Admission for Acute Heart Failure
Changes in Antigen Carbohydrate 125 in Patients Receiving Dapagliflozin following an Admission for Acute Heart Failure Open
Introduction: Antigen carbohydrate 125 (CA125) has emerged as a proxy of fluid overload and inflammation in acute heart failure (AHF). We aimed to evaluate the influence of dapagliflozin on CA125 levels within the first weeks after dischar…
View article: Routine invasive strategy and frailty burden in non-ST-segment elevation acute myocardial infarction
Routine invasive strategy and frailty burden in non-ST-segment elevation acute myocardial infarction Open
Adult patients with frailty and NSTEMI showed different prognosis according to the degree of frailty. A routine invasive strategy does not improve outcomes and might be harmful to the frailest patients.
View article: High-sensitivity C-reactive protein and risk of clinical outcomes in patients with acute heart failure
High-sensitivity C-reactive protein and risk of clinical outcomes in patients with acute heart failure Open
View article: Carbohydrate antigen 125 on epicardial fat and its association with local inflammation and fibrosis-related markers
Carbohydrate antigen 125 on epicardial fat and its association with local inflammation and fibrosis-related markers Open
View article: CA125 outperforms NT-proBNP in the prediction of maximum aerobic capacity in heart failure with preserved ejection fraction and kidney dysfunction
CA125 outperforms NT-proBNP in the prediction of maximum aerobic capacity in heart failure with preserved ejection fraction and kidney dysfunction Open
Background Heart failure with preserved ejection fraction (HFpEF) often coexists with chronic kidney disease (CKD). Exercise intolerance is a major determinant of quality of life and morbidity in both scenarios. We aimed to evaluate the as…
View article: Association between N-terminal pro-brain natriuretic peptide and maximal functional capacity in heart failure with preserved ejection fraction: The modifying role of obesity
Association between N-terminal pro-brain natriuretic peptide and maximal functional capacity in heart failure with preserved ejection fraction: The modifying role of obesity Open
View article: Exercise training response according to baseline ferrokinetics in heart failure with preserved ejection fraction: A substudy of the TRAINING‐HF trial
Exercise training response according to baseline ferrokinetics in heart failure with preserved ejection fraction: A substudy of the TRAINING‐HF trial Open
Background Iron deficiency (ID) is associated with impaired functional capacity in patients with heart failure (HF), even in those with preserved ejection fraction (HFpEF). This study aimed to evaluate the effect of baseline ferrokinetics …
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View article: Improvement in left atrial strain following ferric carboxymaltose in heart failure: an analysis of the Myocardial‐IRON trial
Improvement in left atrial strain following ferric carboxymaltose in heart failure: an analysis of the Myocardial‐IRON trial Open
Aims Iron deficiency (ID) is associated with an impaired cardiac function and remodelling in heart failure (HF). Treatment with ferric carboxymaltose (FCM) has been showed recently to improve biventricular systolic function and ventricular…
View article: Derivation and external validation of machine-learning- models for risk stratification in chest pain with normal troponin
Derivation and external validation of machine-learning- models for risk stratification in chest pain with normal troponin Open
Importance Risk stratification of patients with chest pain and a high-sensitivity cardiac troponin T (hs-cTnT) concentration 180 minutes). Probability thresholds for safe discharge were derived in the derivation cohort. Methods This progno…
View article: Residual ischemia by stress CMR in stable post-STEMI patients. Association with clinical events and implications of guided revascularization
Residual ischemia by stress CMR in stable post-STEMI patients. Association with clinical events and implications of guided revascularization Open
Introduction Stress cardiac magnetic resonance (sCMR) represents a gold standard approach to identify and localize myocardial ischemia. However, in the setting of stable STEMI patients, data on the prognostic implications of residual ische…
View article: Dapagliflozin and short-term changes on circulating antigen carbohydrate 125 in heart failure with reduced ejection fraction
Dapagliflozin and short-term changes on circulating antigen carbohydrate 125 in heart failure with reduced ejection fraction Open
View article: Evolocumab has no effects on heart failure with reduced ejection fraction injury biomarkers: The <scp>EVO‐HF</scp> trial
Evolocumab has no effects on heart failure with reduced ejection fraction injury biomarkers: The <span>EVO‐HF</span> trial Open
Aim Patients with heart failure with reduced ejection fraction (HFrEF) have not been shown to benefit from statins. We hypothesized that, by limiting disease progression in stable HFrEF of ischaemic etiology, the proprotein convertase subt…
View article: Impact of Persistent Microvascular Obstruction Late After STEMI on Adverse LV Remodeling
Impact of Persistent Microvascular Obstruction Late After STEMI on Adverse LV Remodeling Open
View article: Effect of Routine Invasive vs Conservative Strategy in Older Adults With Frailty and Non–ST-Segment Elevation Acute Myocardial Infarction
Effect of Routine Invasive vs Conservative Strategy in Older Adults With Frailty and Non–ST-Segment Elevation Acute Myocardial Infarction Open
Importance To our knowledge, no randomized clinical trial has compared the invasive and conservative strategies in frail, older patients with non–ST-segment elevation acute myocardial infarction (NSTEMI). Objective To compare outcomes of i…
View article: Efficacy of virtual reality reducing anxiety during CTO revascularization: the ReViCTO trial design
Efficacy of virtual reality reducing anxiety during CTO revascularization: the ReViCTO trial design Open
Introduction and objectives: Percutaneous coronary interventions (PCI) of chronic total occlusions (CTO) are long procedures where many patients suffer moderate-to-high level anxiety and pain. Virtual reality (VR) has proven capable of red…
View article: Clinical Predictors and Prognosis of Myocardial Infarction with Non-Obstructive Coronary Arteries (MINOCA) without ST-Segment Elevation in Older Adults
Clinical Predictors and Prognosis of Myocardial Infarction with Non-Obstructive Coronary Arteries (MINOCA) without ST-Segment Elevation in Older Adults Open
A non-neglectable percentage of patients with non-ST elevation myocardial infarction (NSTEMI) show non-obstructive coronary arteries (MINOCA). Specific data in older patients are scarce. We aimed to identify the clinical predictors of MINO…
View article: Supplementary Material for: Peritoneal and Urinary Sodium Removal in Refractory Congestive Heart Failure Patients Included in an Ambulatory Peritoneal Dialysis Program: Valuable for Monitoring the Course of the Disease?
Supplementary Material for: Peritoneal and Urinary Sodium Removal in Refractory Congestive Heart Failure Patients Included in an Ambulatory Peritoneal Dialysis Program: Valuable for Monitoring the Course of the Disease? Open
Introduction: Spot urinary sodium emerged as a useful parameter for assessing decongestion in patients with congestive heart failure (CHF). Growing evidence endorses the therapeutic role of continuous ambulatory peritoneal dialysis (CAPD) …
View article: Peritoneal and Urinary Sodium Removal in Refractory Congestive Heart Failure Patients Included in an Ambulatory Peritoneal Dialysis Program: Valuable for Monitoring the Course of the Disease
Peritoneal and Urinary Sodium Removal in Refractory Congestive Heart Failure Patients Included in an Ambulatory Peritoneal Dialysis Program: Valuable for Monitoring the Course of the Disease Open
Introduction: Spot urinary sodium emerged as a useful parameter for assessing decongestion in patients with congestive heart failure (CHF). Growing evidence endorses the therapeutic role of continuous ambulatory peritoneal dialysis (CAPD) …
View article: Prognostic value of cardiac magnetic resonance early after ST-segment elevation myocardial infarction in older patients
Prognostic value of cardiac magnetic resonance early after ST-segment elevation myocardial infarction in older patients Open
Background older patients with ST-segment elevation myocardial infarction (STEMI) represent a very high-risk population. Data on the prognostic value of cardiac magnetic resonance (CMR) in this scenario are scarce. Methods the registry com…
View article: Risk of death associated with incident heart failure in patients with known or suspected chronic coronary syndrome
Risk of death associated with incident heart failure in patients with known or suspected chronic coronary syndrome Open
Aims Traditional adverse events in chronic coronary syndrome (CCS) include atherothrombotic events but usually exclude heart failure (HF). Data are scarce about how new‐onset HF modifies mortality risk. We aimed to determine the incidence …
View article: Fourier analysis of collagen bundle orientation in myocardial infarction scars
Fourier analysis of collagen bundle orientation in myocardial infarction scars Open
View article: Bending oxygen saturation index and risk of worsening heart failure events in chronic heart failure
Bending oxygen saturation index and risk of worsening heart failure events in chronic heart failure Open
Aims Bendopnea is a clinical symptom of advanced heart failure with uncertain prognostic value. We aimed to evaluate whether bendopnea and the change in oxygen saturation when bending forward (bending oxygen saturation index [BOSI]) are as…